Virtual Screening Approaches Towards the Discovery of Toll-like Receptor 7 (TLR7) Antagonists for the Management of Rheumatoid Arthritis During COVID Infection [0.03%]
虚拟筛选方法发现托尔样受体7(TLR7)拮抗剂用于管理COVID感染期间的类风湿性关节炎
Thangavelu Prabha,Saravanan Thangavelu,Dakshinesh Parameswaran et al.
Thangavelu Prabha et al.
Background: Rheumatoid arthritis(RA) patients prompt to have high level of TLR7, when coronavirus (CoV-2) infect to these patients, further the level of TLR7 cloud be upregulated and leads to severe condition of RA. Since...
The Frequency of Musculoskeletal Disorders and Nerve Entrapment Syndromes Around the Shoulder in a Cohort of Egyptian Patients [0.03%]
埃及患者肩部周围肌肉骨骼疾患和神经卡压综合征的发生率
Dalia Salah Saif,Suzan Omar,Aya Hanafy Ibrahiem et al.
Dalia Salah Saif et al.
Background: Shoulder pain is a common musculoskeletal (MSK) disorder. However, proper diagnosis of shoulder dysfunction and causes of pain remains challenging. ...
The TIM-3/Gal-9 Pathway: A Promising Therapeutic Target for Regulation of Immune Checkpoint in Rheumatoid Arthritis [0.03%]
TIM-3/Gal-9通路:作为类风湿性关节炎免疫检查点调节的有前景的治疗靶标
Debjeet Sur,Riya Pramanik
Debjeet Sur
Rheumatoid arthritis (RA) is a chronic autoimmune ailment that is marked by persistent synovial joint inflammation, which causes joint destruction and other systemic consequences. The immune system is equipped with a wide range of effector ...
Sandip Zine,Dhanashri Kadam,Pranita Lodha
Sandip Zine
Autoimmune diseases are a class of diseases wherein the immune system of the body targets itself through autoreactive T cells and autoantibodies. Autoimmune diseases are classified as organ-specific autoimmune diseases and systemic autoimmu...
Combined Axial and Peripheral Melorheostosis in a Young Boy: A Unique Case [0.03%]
年轻男孩的联合轴性和外周密梁骨病：一个独特的病例
Hesham Hamoud,Ahmed M Elhilasy,Eman E A Elsalam et al.
Hesham Hamoud et al.
Background: Axial melorheostosis is a rare clinical condition with only a few cases identified worldwide. The combination of axial and peripheral melorheostosis has not reported before, to the best of our knowledge. ...
Systemic Sclerosis Complicated by Rapidly Progressive Osteomyelitis: A Case Report [0.03%]
系统性硬化症并发快速进展性骨髓炎1例报告
Angelo Nigro
Angelo Nigro
Background: Systemic sclerosis (SSc) is an autoimmune disorder characterized by progressive fibrosis and vascular complications. Osteomyelitis is a rare but serious complication in patients with systemic sclerosis, partic...
Pallavi Kathoke,Kalyani Thombre,Krishna Radheshyam Gupta et al.
Pallavi Kathoke et al.
Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease that requires early detection and treatment. Currently, we have three categories of slow-acting disease-modifying antirheumatic drugs (DMARDs): (1) c...
Infection Screening and Vaccination of Adult and Pediatric Patients with Autoimmune Inflammatory Rheumatic Diseases: An Emirati Delphi Consensus [0.03%]
阿联酋专家共识：成人及儿科自身免疫性炎症风湿病患者感染筛查和疫苗接种
Ahlam Almarzooqi,Jehad Abdalla,Mohamed Sharif Elsadeg et al.
Ahlam Almarzooqi et al.
Introduction: Patients with autoimmune and inflammatory rheumatic diseases (AIIRD) have an increased susceptibility to infections due to their compromised immune systems and the use of immunosuppressive therapies. Infecti...
The Causal Effects of Lifestyle Factors on Osteoarthritis: A Two-sample Mendelian Randomisation Study [0.03%]
生活方式因素与骨关节炎因果关系的两样本孟德尔随机化研究
Justin Ho,Christopher Chi Hang Mak,Lawrence Chun Man Lau et al.
Justin Ho et al.
Background: Modern sedentary lifestyles are prevalent among individuals with osteoarthritis. However, direct evidence linking such behaviours as causative factors of osteoarthritis remain limited due to the presence of co...
Siming Gao,Hui Song
Siming Gao
Gouty arthritis is a common arthritic disease caused by the deposition of monosodium urate crystals in the joints and the tissues around it. The main pathogenesis of gout is the inflammation caused by the deposition of monosodium urate crys...