Yasser El Miedany
Yasser El Miedany
Recent publications have proposed revisions to disease classification criteria, new definitions of early diagnosis and remission, as well as guidelines for implementing treat-to-target strategies for the management of patients with spondylo...
Cappelli Susanna,Guilpain Philippe,Bellando-Randone Silvia et al.
Cappelli Susanna et al.
The term overlap syndromes (OS) is used to define a group of disorders characterized by the presence, in the same patient, of clinical features typical for more than one definite connective tissue disease (CTD). ...
The concept of early systemic sclerosis following 2013 ACR/EULAR criteria for the classification of systemic sclerosis [0.03%]
2013年ACR/EULAR系统性硬化症分类标准概念下早期系统性硬化症的概念
Gabriele Valentini,Antonella Marcoccia,Giovanna Cuomo et al.
Gabriele Valentini et al.
For many years observational studies and clinical trials on systemic sclerosis (SSc) have been carried out only on patients who met the 1980 American College of Rheumatology-ACR preliminary classification criteria. However, this lead to the...
Choice of Biologic Therapy for Patients with Rheumatoid Arthritis: The Infection Perspective [0.03%]
风湿患者生物制剂选择的感染角度思考
Filip De Keyser
Filip De Keyser
Biologicals revolutionized the treatment of Rheumatoid Arthritis (RA). The targeted suppression of key inflammatory pathways involved in joint inflammation and destruction allows better disease control, which, however, comes at the price of...
Lesley Ann Saketkoo,Dana P Ascherman,Vincent Cottin et al.
Lesley Ann Saketkoo et al.
The lung is one of the most common extra-muscular targets in idiopathic inflammatory myopathies (IIM) and interstitial lung disease (ILD) is a prevalent and often devastating manifestation of IIM. IIM-associated ILD (IIM-ILD) contributes to...
Terry Kit Selfe,Kim E Innes
Terry Kit Selfe
Osteoarthritis of the knee is a major cause of disability among adults worldwide. Important treatment options include nonpharmacologic therapies, and especially symptom management strategies in which patients take an active role. Among thes...
Zoltán Szekanecz,Alisa E Koch
Zoltán Szekanecz
Angiogenesis, the development of new capillaries, is a crucial process in health and disease. The perpetuation of neovascularization in rheumatoid arthritis is highly involved in leukocyte extravasation into the synovium and pannus formatio...
Systemic Sclerosis-Associated Interstitial Lung Disease: Lessons from Clinical Trials, Outcome Measures, and Future Study Design [0.03%]
系统性硬化症相关间质性肺疾病：临床试验、评估指标及未来研究设计的经验与教训
Dinesh Khanna,James R Seibold,Athol Wells et al.
Dinesh Khanna et al.
Pulmonary involvement including interstitial lung disease (ILD) is the leading cause of mortality in patients with systemic sclerosis (scleroderma; SSc). This article reviews the current evidence based medicine regarding available therapies...
Development of Clinical Trial Assessments for the Study of Interstitial Lung Disease in Patients who have Connective Tissue Diseases-Methodological Considerations [0.03%]
结缔组织病患者间质性肺疾病临床试验评估的开发-方法学考虑因素
Dörte Huscher,Lesley Ann Saketkoo,David Pittrow et al.
Dörte Huscher et al.
This review article discusses the proposed methodology that will be utilized to develop core set items for connective tissue disease-associated interstitial lung disease (CTD-ILD). CTD-ILD remain an important enigma in clinical medicine. No...
Zafar Rasheed,Tariq M Haqqi
Zafar Rasheed
With the advent of biological therapies, considerable progress has been made in the treatment of rheumatoid arthritis (RA). These revolutionary therapies owe their origin to the role that cytokines play in the pathophysiology of the disease...