Specific Features of Juvenile Idiopathic Arthritis Patients' Chemokine Profile: The Data of Case-Control Study Analysis [0.03%]
儿童关节炎患者细胞趋化因子特点的病例对照研究数据分析
Arseniy V Rybakov,Karina A Yureva,Vitaliy V Khizha et al.
Arseniy V Rybakov et al.
Background: Juvenile idiopathic arthritis pathogenesis involves a large number of different immune system cells, which are both sources and targets of chemokines, that affect not only their migration but also survival, pr...
Exploring Potential Bioactive Components of Persea americana for the Treatment of Rheumatoid Arthritis through Network Pharmacology [0.03%]
基于网络药理学的鳄梨活性成分治疗类风湿性关节炎的研究
Krishna Swaroop Akey,Esakkimuthukumar M,Saranya R et al.
Krishna Swaroop Akey et al.
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease character-ized by inflammation and joint destruction, leading to significant disability and reduced quality of life. Current treatment options for RA...
Efficacy and Safety of Upadacitinib for Axial Spondyloarthritis: A Systematic Review and Meta-Analysis [0.03%]
乌帕替尼治疗轴性脊柱关节炎疗效和安全性的系统评价和 meta 分析
Ahmed Hamdy G Ali,Asmaa Elganady,Mahmoud Diaa Hindawi et al.
Ahmed Hamdy G Ali et al.
Introduction: Upadacitinib, a selective JAK1 inhibitor, has demonstrated promising results in the treatment of axial Spondyloarthritis (AxSpA). AxSpA management remains challenging since there is a gap in knowledge regard...
Interleukin 18 (-137G/C, -607C/A) Polymorphisms as Genetic Biomarkers of Susceptibility to Systematic Lupus Erythematosus [0.03%]
白细胞介素18(-137G/C，-607C/A)基因多态性作为系统性红斑狼疮易感性遗传标志物的研究
Zahra Rezaieyazdi,Payman Delavar,Houshang Rafatpanah et al.
Zahra Rezaieyazdi et al.
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology. Several studies have suggested that interleukin-18 (IL-18) is associated with SLE pathogenesis. The genotype distribution of IL-...
Rituximab Therapy for Adult Refractory Systemic Lupus Erythematosus with Neurological and/or Psychiatric Presentations: A PRISMACompliant Meta-Analysis [0.03%]
成人难治性系统性红斑狼疮神经精神性表现利妥昔单抗治疗的 meta 分析
Mehran Asad Ayoubi,Maryam Moghaddassi,Mehdi Aloosh
Mehran Asad Ayoubi
Background: Rituximab (RTX) is used off-label for refractory cases of systemic lupus erythematosus (SLE) with extrarenal activity, including neurological and/or psychiatric (N/P) presentations. However, evidence from rand...
Therapeutic Potential of Nanocarriers in the Management of Rheumatoid Arthritis [0.03%]
纳米载体在类风湿性关节炎管理中的治疗潜力
Vishnu Mittal,Anjali Sharma,Devkant Sharma
Vishnu Mittal
RA is characterized by chronic inflammation, joint damage, and systemic complications. Despite available treatments, many patients experience inadequate responses or adverse effects. Novel therapeutic strategies are needed to address these ...
Shanthini Sivaprakasam,Jawahar Natarajan,Jigyasa Singh et al.
Shanthini Sivaprakasam et al.
Gout is a common form of inflammatory arthritis characterized by the deposition of MSU in the joints and surrounding tissues, which results in inflammation and recurrent painful attacks. Currently, xanthine oxidase inhibitors, i.e., Allopur...
A Study on Semaphorin 3A Level in Juvenile-onset Systemic Lupus Erythematosus Patients [0.03%]
血栓形成性半导体3A在系统性红斑狼疮患者中的表达及其作用机制研究
Huda Marzouk,Dina Hesham Ahmed,Hend Mohamed Abu Shady et al.
Huda Marzouk et al.
Background: Juvenile-onset systemic lupus erythematosus (jSLE) is an uncommon yet severe autoimmune/inflammatory condition affecting multiple bodily systems, typically manifest-ing before the age of 18. This disease exhib...
Methotrexate - Safe Backbone for the Treatment of Rheumatoid Arthritis [0.03%]
治疗类风湿性关节炎美洛昔康安全有效的长期 backbone疗法
Marco Krasselt
Marco Krasselt
Methotrexate (MTX) is the primarily used disease-modifying antirheumatic drug (DMARD) for the treatment of Rheumatoid Arthritis (RA). MTX is a safe agent, even when used for years - provided that treatment is regularly monitored and prescri...