The role of oxidative stress on necrotizing enterocolitis in very low birth weight infants [0.03%]
氧化应激在极低出生体重儿坏死性小肠结肠炎发病中的作用研究
Serafina Perrone,Maria Luisa Tataranno,Antonino Santacroce et al.
Serafina Perrone et al.
Necrotizing enterocolitis (NEC) is a devastating and common disease of very low birth weight (VLBW) infants with a mortality rate of 10% to 50% and a significant cause of morbidity in survivors. The incidence of NEC has increased from 5% to...
Christopher Fundakowski,Rosemary Ojo,Ramzi Younis
Christopher Fundakowski
Cystic fibrosis (CF) is a common autosomal recessive genetic disorder where a deletion mutation and subsequent downstream alteration in transmembrane regulator proteins results in increased mucus viscosity. CF manifests clinically with chro...
Zeeshaan U Hasan,Rania Absamara,Mas Ahmed
Zeeshaan U Hasan
Chvostek's Sign was first described in 1876, as a clinical clue associated with patients who suffered from latent tetany, and is induced by percussion of the angle of the jaw. However, over the years many clinicians have called into questio...
Atin Kalra,Shishu Goindi
Atin Kalra
The quest for achieving optimal therapeutic outcomes in pediatric patients has evaded the healthcare professionals for long and often lack of child specific dosage forms and the associated events that follow with it have been considered to ...
Is red meat required for the prevention of iron deficiency among children and adolescents? [0.03%]
红肉对预防儿童和青少年缺铁是否必要？
Savvas C Savva,Anthony Kafatos
Savvas C Savva
Iron deficiency remains the most common nutritional deficiency worldwide despite the fact that global prevention is a high priority. Recent guidelines suggest intake of red meat both in infants and toddlers to prevent iron deficiency. Howev...
Thrombotic complications of neonates and children with congenital nephrotic syndrome [0.03%]
先天性肾病综合征新生儿和儿童的血栓并发症
Keith K Lau,Howard H Chan,Patti Massicotte et al.
Keith K Lau et al.
Congenital nephrotic syndrome (CNS) refers to a disease presenting with massive proteinuria in association with hypoalbuminemia, hyperlipidemia, and edema at birth or within the first three months of life. In the past, most children with CN...
Surfactant-associated proteins: structure, function and clinical implications [0.03%]
与表面活性剂相关的蛋白质：结构、功能及临床意义
Anastasia K Ketko,Steven M Donn
Anastasia K Ketko
Surfactant replacement therapy is now the standard of care for infants with respiratory distress syndrome. As the understanding of surfactant structure and function has evolved, surfactant-associated proteins are now understood to be essent...
Nonalcoholic fatty liver disease in children: recent practice guidelines, where do they take us? [0.03%]
儿童非酒精性脂肪肝近期指南及展望
Ashish Aggarwal,Kanika Puri,Suraj Thangada et al.
Ashish Aggarwal et al.
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in children and adolescents in the United States. It is strongly associated with childhood obesity, insulin resistance and metabolic syndrome. Althou...
Kanwal Kher,Kirtida Mistry
Kanwal Kher
At birth, GFR and tubular function of neonates is compromised as compared to older children and adults. These functions are even less developed in premature infants. These facts have a direct bearing on drug dosing, fluid and electrolyte ad...
Shamir Tuchman
Shamir Tuchman
Disorders of calcium and phosphorus homeostasis present both acute and chronic clinical consequences for newborns. The etiologies responsible range from iatrogenic, idiopathic, and inherited metabolic abnormalities. Maintenance of physiolog...