Emily Quinn,Rose McGee,Regina Nuccio et al.
Emily Quinn et al.
The development of tumors within the first month of life is extremely rare and this very young age at presentation should raise concern for an underlying cancer predisposition syndrome. This chapter discusses genetic predisposition to neona...
Neonatal Germ Cell Tumors [0.03%]
新生儿生殖细胞肿瘤
John A Sandoval,Regan F Williams
John A Sandoval
Excluding hemangiomas, germ cell tumors (GCTs) are the most common neoplasm in neonates, comprising a wide range of benign and malignant tumors with unique histological diversity. Although these tumors are relatively rare, antenatal ultraso...
New Insights into the Surgical Management of Tetralogy of Fallot: Physiological Fundamentals and Clinical Relevance [0.03%]
法洛四联症外科治疗的新见解：生理基础与临床意义
Thierry Bove,Katrien François,Daniel De Wolf
Thierry Bove
The surgical treatment of tetralogy of Fallot can be considered as a success story in the history of congenital heart diseases. Since the early outcome is no longer the main issue, the focus moved to the late sequelae of TOF repair, i.e. th...
Molecular Subgrouping of Medulloblastoma: Impact Upon Research and Clinical Practice [0.03%]
髓母细胞瘤的分子分组及其对研究和临床实践的影响
Tejpal Gupta,Neelam Shirsat,Rakesh Jalali
Tejpal Gupta
Medulloblastoma, the most common primary pediatric malignant brain tumor is a molecularly heterogeneous disease with different developmental origins, distinct phenotypes, diverse biological behaviour, and contrasting clinical outcomes. The ...
Non-transfusion Dependent Thalassemias: A Developing Country Perspective [0.03%]
非输血依赖性地中海贫血的诊疗（发展中国家视角）
Somnath Mukherjee,Rashmi R Das,Babita Raghuwanshi
Somnath Mukherjee
Non-transfusion-dependent thalassemias (NTDT) encompass a group of hereditary chronic hemolytic anemia, which, as the name indicates, not require regular blood transfusion for survival. These include β-thalassemia intermedia, hemoglobin E/...
A Pilot Study to Assess the Vestibular Apparatus Function with Videonystagmography During Chronic Otitis Media with Effusion [0.03%]
慢性中耳炎积液患者膜迷路功能试验的临床研究——视频眼震图的应用价值评估试点研究
Issam Saliba,Chady Dagher,Elie El-Zir et al.
Issam Saliba et al.
Objective: To assess the effect of chronic middle ear effusion (CMEE) on balance and equilibrium. Material and methods: Prospective stu...
Role of Fibroblast Growth Factor 21 (FGF21) in the Regulation of Statural Growth [0.03%]
成纤维细胞生长因子21（FGF21）在调节体格生长中的作用
Tal Grunwald,Francesco De Luca
Tal Grunwald
In this review, we discuss the evidence supporting the causative role of increased FGF21 expression in reduced GH action and impaired longitudinal bone growth. Fibroblast Growth Factor (FGF) 21 (FGF21) is a member of a subfamily of FGFs whi...
Alissa J Roberts,Craig E Taplin
Alissa J Roberts
Exercise is important in the management of type 1 diabetes mellitus (T1DM). Modern diabetes care includes the goal that all youth meet guidelines for regular physical activity. Evidence suggests regular physical activity improves cardiovasc...
Systematic Review and Quality Appraisal of International Guidelines on Perinatal Care of Extremely Premature Infants [0.03%]
极早早产儿围生期护理的国际指南系统回顾及质量评估
Navneet Binepal,Brigitte Lemyre,Sandra Dunn et al.
Navneet Binepal et al.
Objectives: Clinicians often refer to published or local guidelines when counselling expectant parents on perinatal care decisions at the limits of viability. The objectives of this study are to systematically review the ...
Joseph R DiFranza
Joseph R DiFranza
This review will describe the biological and behavioral aspects of nicotine addiction as it develops during adolescence and advances over a lifetime. Symptoms of physical nicotine dependence typically appear when adolescents are smoking onl...