An Insight into Emerging Phytocompounds for Glioblastoma Multiforme Therapy [0.03%]
探究胶质母细胞瘤治疗的植物源化合物进展
Vijeta Prakash,Reema Gabrani
Vijeta Prakash
Despite intense research in the field of glioblastoma multiforme (GBM) therapeutics, the resistance against approved therapy remains an issue of concern. The resistance against the therapy is widely reported due to factors like clonal selec...
Anti-angiogenic Potential of Trans-chalcone in an In Vivo Chick Chorioallantoic Membrane Model: An ATP Antagonist to VEGFR with Predicted Blood-brain Barrier Permeability [0.03%]
茋类化合物反式查尔康因抗血管生成的潜力：鸡胚尿囊膜模型中VEGFR的ATP拮抗剂及预测的血脑屏障通透性
Anna Senrung,Tanya Tripathi,Nikita Aggarwal et al.
Anna Senrung et al.
Background: Glioblastoma multiforme (GBM) is characterized by massive tumorinduced angiogenesis aiding tumorigenesis. Vascular endothelial growth factor A (VEGF-A) via VEGF receptor 2 (VEGFR-2) constitutes majorly to driv...
Combined Administration of Metformin and Vitamin D: A Futuristic Approach for Management of Hyperglycemia [0.03%]
二甲双胍和维生素D联合使用：未来治疗高血糖的新思路
Sakshi Tyagi,Shalini Mani
Sakshi Tyagi
Diabetes is a series of metabolic disorders that can be categorized into three types depending on different aspects associated with age at onset, intensity of insulin resistance, and beta- cell dysfunction: Type 1 and 2 Diabetes, and Gestat...
Endothelial Dysfunction under the Scope of Arterial Hypertension, Coronary Heart Disease, and Diabetes Mellitus using the Angioscan [0.03%]
从高血压、冠状动脉心脏病和糖尿病角度看内皮功能障碍（使用Angioscan）
Basheer Abdullah Marzoog
Basheer Abdullah Marzoog
Background: Cardiovascular disease and diabetes mellitus are among the leading causes of mortality. Objectives: Our study evaluated end...
Ahmad Abdulrahman Almeman,Yousef Obaid Alharbi,Abdulaziz Sulaiman Alwahhabi et al.
Ahmad Abdulrahman Almeman et al.
Background: Beta-blockers are essential agents in the management of cardiovascular diseases, such as heart failure, acute myocardial infarction (MI), and cardiac arrhythmias. However, there are diurnal variations in the c...
Cardioprotective Role of Tinospora cordifolia against Trimethylamine-NOxide and Glucose Induced Stress in Rat Cardiomyocytes [0.03%]
卡波果提取物对TMAO和葡萄糖诱导的心肌细胞损伤的保护作用
Shivani Singhal,Vibha Rani
Shivani Singhal
Background: Type 2 diabetes has become a concern issue that affects the quality of life and can increase the risk of cardiac insufficiency elevating the threat to the life safety of patients. A recognized cause of cardiac...
Evaluation of Enhanced Cytotoxicity Effect of Repurposed Drug Simvastatin/ Thymoquinone Combination against Breast Cancer Cell Line [0.03%]
评估并提高雷帕霉素同系物西立伐他汀/藤黄质复合物的抗癌活性
Pallavi Kumari,Shweta Dang
Pallavi Kumari
Introduction: The repurposing of drugs for their anticancer potential is gaining a lot of importance in drug discovery. Aims: The prese...
Abhimanyu Chauhan,Chakresh Kumar Jain
Abhimanyu Chauhan
In recent years, there has been increasing global concern about the rising prevalence and rapid progression of psychosomatic disorders (PD). This surge can be attributed to irregular biological conditions and the increasingly stressful life...
Lipotoxicity, ER Stress, and Cardiovascular Disease: Current Understanding and Future Directions [0.03%]
脂毒性、内质网应激与心血管疾病：现状和未来方向
Smriti Shreya,Md Jahangir Alam,Anupriya Anupriya et al.
Smriti Shreya et al.
The endoplasmic reticulum (ER) is a sub-cellular organelle that is responsible for the correct folding of proteins, lipid biosynthesis, calcium storage, and various post-translational modifications. In the disturbance of ER functioning, unf...
Harmanjit Kaur,Samneet Singh,Sai Gautham Kanagala et al.
Harmanjit Kaur et al.
Background: Herbal remedies are used by 80% of the Asian population in primary health care as per WHO. According to current research, the herbal medicine market was valued at nearly USD 166 billion in 2021 and is expected...