MOTS-c as a Potential Diagnostic-Prognostic Biomarker for Myocardial Infarction [0.03%]
MOTS-c作为心肌梗死诊断和预后生物标志物的潜力
Abdülkadir Çakmak,Burak Yazgan
Abdülkadir Çakmak
Background: Myocardial infarction (MI) is a disease characterised by myocardial necrosis due to acute and prolonged ischaemic hypoxia in the coronary arteries. MOTS-c is a mitochondrial- derived peptide that has been repo...
Adropin and Spexin Peptides Ameloriate Cardiac Inflammation, Matrix Metalloproteinases, and Vascular Response [0.03%]
腺苷肽和Spexin多肽缓解心脏炎症、基质金属蛋白酶和血管反应
Gülsün Memi,Burak Yazgan,Ebru Taştekin
Gülsün Memi
Background: Chronic renal failure (CRF) triggers chronic systemic inflammation and causes vascular calcification, a prominent contributor to the progression of cardiovascular disease. Adropin and spexin peptides regulate ...
The Challenge of Detecting Heparin-induced Thrombocytopenia (HIT) in a Developing Country: A Systematic Review [0.03%]
在发展中国家检测肝素诱导的血小板减少症(HIT)的挑战：系统回顾
Hadi Rezaei,Mohammad Ghorbani,Hassan Mansouritorghabeh
Hadi Rezaei
Introduction: Approximately 3% of patients treated with heparinoids develop heparin- induced thrombocytopenia (HIT). Although HIT is characterized by thrombocytopenia, type 2 HIT is associated with a high risk of thrombot...
Oxidative Stress in Cardiovascular Diseases: Mechanisms and Exploring Advanced Therapies [0.03%]
氧化应激在心血管疾病中的机制及探索先进疗法
Dushyant -,Balram -,Gurvirender Singh et al.
Dushyant - et al.
The recognition of oxidative stress as a factor influencing the development and progression of cardiovascular diseases (CVDs) is growing. By producing such reactive oxygen species (ROS) in diverse areas within cells, including mitochondria ...
Long-term Sustained Response to Lenalidomide after Clearance of Bone Marrow Blasts by Azacytidine in High-risk Myelodysplastic Syndromes with Del5q: A Case Report [0.03%]
地西他滨清髓后伦德替尼在伴有5q缺失高危骨髓增生异常综合症中的长期有效维持一例报告
Pasquale Niscola,Marco Giovannini,Valentina Gianfelici et al.
Pasquale Niscola et al.
Introduction: This report discusses a rare case involving a patient with high-risk (HR) Del(5q) myelodysplastic syndrome (MDS) who achieved a long-term response to lenalidomide after having received six cycles of azacytid...
Emerging Biomarkers for Assessing Thrombotic Risk in Patients Receiving Direct Oral Anticoagulants (DOACs) [0.03%]
直接口服抗凝药物使用者的新型血栓形成风险生物标志物评估指标
Ashmi Sabana M,Alwin Simon M
Ashmi Sabana M
Direct Oral Anticoagulants (DOACs) have transformed the management of thrombotic disorders, offering a more convenient and effective alternative to traditional vitamin K antagonists (VKAs). However, assessing thrombotic risk in patients tre...
Novel Pathway and Recent Advances for Targeting Sickle Cell Anemia through Novel Drug Delivery System [0.03%]
新的途径和最近通过新型药物递送系统靶向镰状细胞贫血的进展
Savita Chouhan,Ajazuddin,Parag Jain
Savita Chouhan
Red blood cells with sickle cell anemia (SCA) have an irregular shape, and it is a genetic blood condition that can cause several problems and shorten life expectancy. Traditional treatments have focused on symptom management, but recent ad...
Anti-thrombotic Mechanisms of Echinochrome A on Arterial Thrombosis in Rats: In-Silico, In-Vitro and In-Vivo Studies [0.03%]
海参素A抗动脉血栓机制的体内、体外及分子对接研究
Marina Lotfy Khalaf,Amel Mahmoud Soliman,Sohair Ramadan Fahmy et al.
Marina Lotfy Khalaf et al.
Background: Arterial thrombosis is one of the most significant healthcare concerns in the world. Echinochrome A (Ech-A) is a natural quinone pigment isolated from sea urchins. It has a variety of medicinal values associat...
A Comprehensive Insight on Pharmacological Properties of Cilnidipine: A Fourth-generation Calcium Channel Blocker [0.03%]
西尼地平药理作用的全面见解：第四 generation钙通道阻滞剂综述
Renu Kadian,Arun Nanda
Renu Kadian
Preventing the development of cardiovascular problems is a key objective of antihypertensive drugs. Many of the non-pressure related coronary risk factors for hypertension are thought to be connected to an increase in sympathetic activity. ...
Cardio-metabolic Disorders Affected by Genetic Polymorphisms Related to Premature Menopause [0.03%]
早发性绝经相关基因多态性与心血管代谢性疾病的关系研究
Mohammad Reza Mirinezhad,Hamideh Safarian Bana,Maliheh Aghsizadeh et al.
Mohammad Reza Mirinezhad et al.
Background: Premature menopause (PM) is defined as the end of ovulation before the age of 40 years, a condition commonly referred to as primary ovarian insufficiency. It has been shown there is an association between earl...