Single-Cell and Machine Learning Analysis Reveal Novel Inflammatory Macrophage Subtypes and Biomarkers in Periodontitis [0.03%]
单细胞和机器学习分析揭示了牙周炎中新型的炎症性巨噬细胞亚型和生物标志物
Shaoyong Chen,Jun Zhao,Jiayi Hang et al.
Shaoyong Chen et al.
Background: Periodontitis (PD) is a chronic inflammatory disease marked by immune dysregulation and progressive tissue destruction. Macrophages play a pivotal role in PD pathogenesis; however, their heterogeneity, molecul...
Musculoskeletal Analysis after Internal Fixation of Condylar Fracture: A Retrospective Study [0.03%]
下颌髁突骨折内固定术后的肌肉骨骼分析：一项回顾性研究
Lingtong Bu,Yuxin Zhang,Guanlin Qu et al.
Lingtong Bu et al.
Background: To evaluate musculoskeletal modification after open reduction and internal fixation of condylar fracture by clinical examinations and computed tomography reconstruction to guide the clinical therapeutic strate...
Effectiveness of Bioactive Glass-Based Toothpaste for Early Childhood Caries Prevention: A Randomized Controlled Trial [0.03%]
生物活性玻璃牙膏预防幼儿龋病的疗效：一项随机对照试验
Ting Li,Haiying Guo,Chang Liu et al.
Ting Li et al.
Aim: Early childhood caries (ECC) remains a significant global health challenge. While fluoride-based treatments are the standard, bioactive glass (BAG) has emerged as a promising alternative for caries prevention. This c...
Curcumin suppresses EMT to alleviate oral submucous fibrosis progression through XIST/miR-25-3p-mediated inactivation of the TGF-β1/Smads signalling pathway [0.03%]
姜黄素通过XIST/miR-25-3p介导的TGF-β1/Smads信号通路失活抑制EMT以缓解口腔粘膜纤维化进展
Qian Min,Yao Liu,Jian Liu et al.
Qian Min et al.
Background: Oral submucous fibrosis (OSF) is a chronic oral disease with a tendency to carcinogenesis. At present, the treatment of OSF is limited and ineffective, and there is an urgent need to find new effective drugs a...
Distribution of Helicobacter pylori in the Oral Cavity of Patients With Tooth Extractions at Various Locations and Ages [0.03%]
不同年龄拔牙患者口腔各部位 Hp 分布状况分析
Masakazu Hamada,Ryota Nomura,Yuko Ogaya et al.
Masakazu Hamada et al.
Background: Helicobacter pylori is well known to cause gastric cancer, gastric ulcers and duodenal ulcers. The oral cavity has been implicated as a reservoir of H. pylori in adulthood. However, there are currently no deta...
Inhibition of IRF4 Promoted Alveolar Bone Regeneration in Periodontitis by Inhibiting GPX4-Mediated Ferroptosis [0.03%]
通过抑制GPX4介导的铁死亡促进牙周炎的牙槽骨再生及IRF4的调控作用
Yan Dai,Binglu Shi,Jingyu Wang et al.
Yan Dai et al.
Background: To investigate the role of interferon regulatory factor 4 (IRF4) in regulating glutathione peroxidase 4 (GPX4)-mediated ferroptosis and its implications for bone homeostasis in periodontitis. ...
Reflections on Digital Simulation in Dental Morphology Education: Insights from a Randomized Controlled Trial [0.03%]
数字化仿真在牙合面形态学教育中应用的思考——随机对照试验的新启示
Carlos M Ardila,Anny Marcela Vivares-Builes,Eliana Pineda- Vélez
Carlos M Ardila
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation [0.03%]
炎症牙周膜干细胞凋亡体对M1型巨噬细胞极化的效应及机制研究
Jinlong Weng,Zeyu Zhang,Liting Zeng et al.
Jinlong Weng et al.
Background: Periodontitis is a widespread infective disease that causes inflammation and periodontal tissue defects. The host's immune regulatory mechanisms play a critical role in the pathogenesis and progression of peri...
C1QBP Drives M2 Macrophage Polarization Via TRAF2-CCL2 to Promote Oral Squamous Cell Carcinoma Progression [0.03%]
C1QBP通过TRAF2-CCL2驱动M2型巨噬细胞极化以促进口腔鳞状细胞癌进展
Xiyuan Qin,Kai Kang,Bowen Zhu et al.
Xiyuan Qin et al.
Introduction and aims: Oral squamous cell carcinoma (OSCC), frequently observed in the head and neck region, possesses mechanisms that have yet to be thoroughly clarified. Poor prognosis in OSCC is closely linked to the p...