David Calderón Guzmán,Norma Osnaya Brizuela,Maribel Ortiz Herrera et al.
David Calderón Guzmán et al.
The ability and facility of magnesium (Mg2+) and zinc (Zn2+) to interact with phosphate ions confer them the characteristics of essential trace elements. Trace elements are extremely necessary for the basic nucleic acid chemistry of cells o...
Pan-Immune-Inflammatory Value Predicts the 3 Months Outcome in Acute Ischemic Stroke Patients after Intravenous Thrombolysis [0.03%]
全面的免疫炎症评分可预测静脉溶栓治疗急性缺血性卒中患者三个月的转归效果
Shan Wang,Lulu Zhang,Huan Qi et al.
Shan Wang et al.
Background and purpose: Immune and inflammatory response plays a central role in the clinical outcomes of stroke. This study is aimed to explore the clinical significance of the new inflammation index named pan-immune-inf...
Intravenous Thrombolysis is Effective in Mild Stroke Patients with an Admission NIHSS Score of 3 to 5 [0.03%]
NIHSS评分在3-5分的轻型卒中患者可从静脉溶栓治疗中获益
Kai Zhang,Lin Han
Kai Zhang
Background and purpose: The role of intravenous thrombolysis in patients with acute mild ischemic stroke remains highly controversial. Therefore, this study aims to analyze the efficacy and safety of intravenous thromboly...
Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders [0.03%]
小胶质细胞在阿尔茨海默病和其他神经退行性疾病中的重要作用
Kenneth Maiese
Kenneth Maiese
Causal Effects of Blood Metabolites and Obstructive Sleep Apnea: A Mendelian Randomization Study [0.03%]
血代谢物和阻塞性睡眠呼吸暂停的因果效应：一项孟德尔随机化研究
Jinghao Wu,Yinghao Yang,Yun Chao Wang et al.
Jinghao Wu et al.
Background: Obstructive sleep apnea (OSA) is one of the most common forms of sleep-disordered breathing. Studies have shown that certain changes in metabolism play an important role in the pathophysiology of OSA. However,...
Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons [0.03%]
SMURF2介导的FOXO4泛素化调节皮质神经元缺血再灌注诱导的细胞焦亡
Bin Yan,Yan Jin,Song Mao et al.
Bin Yan et al.
Background: Smad ubiquitination regulatory factor 2 (Smurf2) has been observed to alleviate ischemia-reperfusion injury. This study sought to explore the molecular mechanism of Smurf2-mediated forkhead box O4 (FOXO4) ubiq...
Targeting the AKT/mTOR/p70S6K Pathway for Oligodendrocyte Differentiation and Myelin Regeneration in Neurological Disorders [0.03%]
针对神经性疾病中少突胶质细胞分化和髓鞘再生的AKT/mTOR/p70S6K信号通路干预研究
Chen Ge,Changwei Li
Chen Ge
Background: The AKT/mTOR/p70S6K pathway has been shown to potentially promote spinal cord injury (SCI) repair in rats. However, its exact mechanism and beyond needs to be further explored. ...
Bone Marrow Mesenchymal Stem Cell Exosomal miR-345-3p Ameliorates Cerebral Ischemia-reperfusion Injury by Targeting TRAF6 [0.03%]
骨髓间充质干细胞来源外泌体miR-345-3p通过靶向TRAF6缓解缺血再灌注脑损伤
Dan Hou,Lei Zhang,Yujie Hu et al.
Dan Hou et al.
Introduction: The purpose of this study was to investigate the effects of bone marrow mesenchymal stem cells (BMSCs) exosomal miR-345-3p and tumor necrosis factor receptorassociated factor 6 (TRAF6) on cerebral ischemia r...
Electroacupuncture Pretreatment Alleviates Cerebral Ischemia-reperfusion Injury by Down-regulating Mir-155-5p [0.03%]
电针预处理通过下调Mir-155-5p缓解缺血再灌注脑损伤
Xuejing Li,Ying Wang,Xiang Zhou et al.
Xuejing Li et al.
Background: Increasing evidence shows that electroacupuncture pretreatment (EP) plays a crucial role in cerebral ischemia-reperfusion (I/R) injury, and cerebral I/R injury is the most serious complication of ischemic stro...