Therapeutic Applications of Natural Flavonoids Against Alzheimer's Disease-like Pathology: Special Focus on PI3K/Akt and Nrf2 Signaling Pathways [0.03%]
天然黄酮类化合物治疗阿尔茨海默病的潜在机制及应用进展:focus于PI3K/AKT和NRF2信号通路
Niraj Kumar Singh,Nikita Varshney
Niraj Kumar Singh
The PI3K/AKT and Nrf2 signaling systems are essential for neurogenesis, synaptic plasticity, and cellular survival, and their dysregulation has been linked to the progression of Alzheimer's disease (AD). Due to its complex pathophysiology, ...
Prognostic Value of PHR and FHR for Outcomes in Acute Ischemic Stroke Patients with Large Artery Occlusion Undergoing Endovascular Treatment [0.03%]
PHR和FHR对大动脉闭塞急性缺血性卒中患者血管内治疗预后的预测价值
Zhi Zhang,Yixin Lin,Yunpeng Liu et al.
Zhi Zhang et al.
Introduction: Acute ischemic stroke (AIS) is linked to dysregulated immuneinflammatory responses. The platelet-to-high-density lipoprotein cholesterol ratio (PHR) and fibrinogen-to-high-density lipoprotein cholesterol rat...
Causal Association Between Cerebrospinal Fluid Metabolites and Stroke: A Mendelian Randomization Study [0.03%]
脑脊液代谢产物与卒中的因果关联：一项孟德尔随机化研究
Xue Jiang,Fei Xie,Yiwei Sun et al.
Xue Jiang et al.
Introduction: Stroke is a leading cause of death and disability globally, influenced by genetic, environmental, and metabolic factors. Although cerebrospinal fluid (CSF) metabolites are closely linked to stroke, their cau...
Association of Stress Hyperglycemia Ratio, and Glucose-albumin Ratio with 90-day Prognosis in Acute Ischemic Stroke Mediating Role of Systemic Inflammatory Response Index [0.03%]
急性缺血性卒中患者应激性高血糖比值及糖化血红蛋白与90天预后的关联及全身炎症反应指数的介导作用
Wanhui Peng,Xinyi Yang,Yongxing Deng et al.
Wanhui Peng et al.
Introduction: The impact of integrated glycemic indices on acute ischemic stroke (AIS) prognosis remains unclear. This study assessed the correlation between the stress hyperglycemia ratio (SHR) and the glucose-to-albumin...
Circadian Patterns of Heart Rate and Heart Rate Variability in Wake-up Stroke: Evidence of Parasympathetic Dysregulation [0.03%]
醒后卒中的心率及心率变异性昼夜节律变化：副交感神经调节异常的证据
Jiann-Der Lee,Yen-Chu Huang,Meng Lee et al.
Jiann-Der Lee et al.
Introduction: Although ischemic stroke is associated with complex changes in the autonomic nervous system, the circadian patterns of heart rate (HR) and heart rate variability (HRV) in wake-up stroke (WUS) remain poorly u...
Effect of 3',4'-dihydroxy Flavonol Supplementation for One Week on Renal Functions and Lipid Peroxidation as Distant Organ Damage After Brain Ischemia-reperfusion in Rats [0.03%]
摄取花色苷3，4-二羟基黄烷醇一周对脑缺血再灌注大鼠肾功能及脂质过氧化作用的影响研究
Merve Gulen,Tugce Aladag,Gozde Acar et al.
Merve Gulen et al.
Introduction: The objective of this study was to investigate the effects of 3',4'- dihydroxyflavonol (DiOHF) on oxidative and antioxidant systems in kidney tissue and on renal function as distant organ damage following br...
Anandamide as a Therapeutic Target for Alleviating Neuropathic Pain and Inflammation in Rat Models [0.03%]
阿纳达胺在减缓大鼠模型神经痛和炎症中的治疗靶点作用研究
Himanshu Sharma,Shahbaz Khan,Alka Lohani et al.
Himanshu Sharma et al.
Introduction: Anandamide (AEA), an endocannabinoid, has demonstrated analgesic and anti-inflammatory properties in various experimental models. However, the mechanisms underlying its role in neuropathic pain and inflammat...
Levetiracetam Monotherapy and its Combination with Phenytoin: Exploring Novel Biomarkers in Pediatric Epilepsy [0.03%]
利鲁唑单药及其与苯妥英联合治疗的新型生物标志物在儿科癫痫中的研究
Hara Prasad Mishra,Rachna Gupta,Manish Narang et al.
Hara Prasad Mishra et al.
Introduction: Epilepsy is a neurological disorder characterized by recurrent seizures that can cause long-standing disturbance of normal brain function. It may adversely affect academic performance, behavior, emotional ad...
Ischemic Postconditioning Attenuates Cerebral Ischemic Injury by Suppressing the Ferroptosis-associated Gene NOX4 [0.03%]
缺血后处理通过抑制铁死亡相关基因NOX4减轻脑缺损伤
Ying Zhu,Qike Wu,Can Xu et al.
Ying Zhu et al.
Introduction: This study investigated the neuroprotective mechanisms of ischemic postconditioning (IPostC) in ischemic stroke, focusing on ferroptosis and the regulatory role of the ferroptosis-related gene NADPH oxidase ...
Global Burden of Diet High in Processed Meat-related Stroke, 1990-2021 [0.03%]
1990年到2021年加工肉制品相关中风的全球疾病负担
Yi Wang,Huiying Huang,Chao You et al.
Yi Wang et al.
Introduction: This study aimed to analyze the global, regional, and national burden and trends of stroke related to high consumption of processed meat from 1990 to 2021, using data from the Global Burden of Disease (GBD) ...