C Kaur,E A Ling
C Kaur
The blood brain barrier (BBB) plays an important role in the homeostatic regulation of the brain microenvironment and maintains the immune-privileged status of the brain by restricting the entry of T lymphocytes. Structurally, the BBB is fo...
Under the microscope: focus on Chlamydia pneumoniae infection and multiple sclerosis [0.03%]
显微镜下的支原体肺炎与多发性硬化症
Enrico Fainardi,Massimiliano Castellazzi,Silva Seraceni et al.
Enrico Fainardi et al.
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the Central Nervous System (CNS) of supposed autoimmune origin whose etiology still remains unknown. Epidemiological studies suggest that MS pathogenesis could be re...
Prolonged reversal of long-term potentiation that is N-methyl-D-aspartate receptor independent: implications for memory formation [0.03%]
一种与N-甲基-D天冬氨酸受体无关的长期抑制作用：对记忆形成的意义
Na-Na Shi,Ma-Li Jiang,Li Zhang et al.
Na-Na Shi et al.
Reversal of long-term potentiation (LTP) by low-frequency stimulation (LFS) is often referred to as depotentiation (DP), a phenomenon that is time-dependent. The present study aimed to determine whether LTP could still be reversed when the ...
Effects of melatonin on ischemic spinal cord injury caused by aortic cross clamping in rabbits [0.03%]
褪黑素对兔主动脉夹闭引起的脊髓缺血性损伤的影响
Ayhan Korkmaz,Eser Oz Oyar,Ozgür Kardeş et al.
Ayhan Korkmaz et al.
Spinal cord injury remains a devastating complication of thoracic and thoracoabdominal aortic operations. We aimed to investigate neuro-protective role of melatonin administered to rabbits before ischemia against ischemia-reperfusion (IR) i...
Nifedipine inhibits the progression of an experimentally induced cerebral aneurysm in rats with associated down-regulation of NF-kappa B transcriptional activity [0.03%]
硝苯地平通过下调NF-κB转录活性抑制实验性颅内动脉瘤进展
Tomohiro Aoki,Hiroharu Kataoka,Ryota Ishibashi et al.
Tomohiro Aoki et al.
Cerebral aneurysm (CA) causes a life-threatening subarachnoid hemorrhage. However, no effective medical treatment to prevent the growth of CA is available. Nifedipine, a widely used calcium antagonist, was shown to improve endothelial funct...
Chronic cerebral hypoperfusion protects against acute focal ischemia, improves motor function, and results in vascular remodeling [0.03%]
慢性脑低灌注对急性局灶性缺血的保护作用、改善运动功能及血管重塑
Seo Hyun Kim,Eun Hee Kim,Byung In Lee et al.
Seo Hyun Kim et al.
Atherosclerosis may cause severe stenosis of the arteries supplying the brain, which induces chronic cerebral hypoperfusion. Although an infarction often occurs in this area, it is uncertain how brain vessels respond to the chronic hypoperf...
Transient disruption of fear-related memory by post-retrieval inactivation of gastrin-releasing peptide or N-methyl-D-aspartate receptors in the hippocampus [0.03%]
海马胃泌素释放肽或N-甲基-D天冬氨酸受体在巩固恐惧记忆中的作用
Tatiana Luft,Olavo B Amaral,Gilberto Schwartsmann et al.
Tatiana Luft et al.
Molecular accounts of memory consolidation suggest that new learning generates persistent synaptic modifications through activation of an extensive set of neuronal receptors and intracellular signal transduction pathways, accompanied by RNA...
Angelica injection reduces cognitive impairment during chronic cerebral hypoperfusion through brain-derived neurotrophic factor and nerve growth factor [0.03%]
Angelica注射通过脑源性神经营养因子和神经生长因子减少慢性脑低灌注的认知障碍
Ping Zheng,Junjian Zhang,Hanxing Liu et al.
Ping Zheng et al.
The current study investigated whether chronic cerebral hypoperfusion produced by permanent bilateral common carotid artery occlusion (2-vessel occlusion (2-VO)) induced cognitive impairment and whether angelica injections alleviated the im...
Repeated restraint and nerve growth factor administration in male and female mice: effect on sympathetic and cardiovascular mediators of the stress response [0.03%]
重复限制和神经生长因子在雄性和雌性小鼠中的作用：对交感神经和心血管介质的影响
Luigi Manni,Veronica Di Fausto,Marco Fiore et al.
Luigi Manni et al.
Chronic stress and increased sympathetic nerve activity have been associated with cardiovascular disorders such as hypertension, myocardial infarction and stroke. The aim of this study was to investigate the role of nerve growth factor (NGF...