Kenneth Maiese
Kenneth Maiese
Assessment of short- and long-term outcomes of patients hospitalized with intracerebral hemorrhage [0.03%]
脑出血住院患者的短期和长期预后评估
Chih-Ming Lin,Wayne Feng
Chih-Ming Lin
The aim of this study was to assess short- and long-term outcomes of patients hospitalized with intracerebral hemorrhage (ICH) in South Carolina. Patients with a primary diagnosis of ICH (ICD-9-CM code 431) discharged during 2002 were ident...
Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity [0.03%]
姜黄素通过调节多种促凋亡和抗凋亡信号通路来对抗对乙酰氨基酚引起的毒性作用
Elida Bulku,Sidney J Stohs,Lorraine Cicero et al.
Elida Bulku et al.
Curcumin (CUR; diferuloylmethane), a rhizome extract of Curcuma Longa L. is commonly used as a food coloring and flavoring agent. Although oriental and Ayurvedic medicines have traditionally used CUR in the treatment of diseases, convention...
Vascular endothelial growth factor: adaptive changes in the neuroglialvascular unit [0.03%]
血管内皮生长因子：神经胶质血管单元的适应性变化
Enrike G Argandoña,Harkaitz Bengoetxea,Naiara Ortuzar et al.
Enrike G Argandoña et al.
Brain postnatal development is modulated by adaptation and experience. Experience-mediated changes increase neuronal activity leading to increased metabolic demands that involve adaptive changes including ones at the microvascular network. ...
Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling involving Bad, Bax, Bim, and Bcl-xL [0.03%]
Wnt1诱导的信号途径蛋白1（WISP1）通过磷脂酰肌醇3激酶/ Akt1和涉及Bad，Bax，Bim和Bcl-xL的凋亡线粒体信号传导阻止神经退行性病变
Shaohui Wang,Zhao Zhong Chong,Yan Chen Shang et al.
Shaohui Wang et al.
Wnt1 inducible signaling pathway protein 1 (WISP1) is a member of the CCN family of proteins that determine cell growth, cell differentiation, immune system activation, and cell survival in tissues ranging from the cardiovascular-pulmonary ...
Amanda Valnier Steckert,Samira Silva Valvassori,Francielle Mina et al.
Amanda Valnier Steckert et al.
The present study aims to investigate the effects of protein kinase C using the inhibitor Tamoxifen (TMX) on oxidative stress in a rat animal model of mania induced by d-amphetamine (d-AMPH). In the reversal model, d-AMPH or saline (Sal) we...
Flavonoids protect cerebrovascular endothelial cells through Nrf2 and PI3K from β-amyloid peptide-induced oxidative damage [0.03%]
黄酮类通过Nrf2和PI3K保护脑血管内皮细胞免于β-淀粉样肽诱导的氧化损伤
Yuan-Di Xi,Huan-Ling Yu,Juan Ding et al.
Yuan-Di Xi et al.
β-amyloid peptides (Aβ) induced cerebrovascular dysfunction has been recognized as a vital factor involved in the pathogenesis of neurodegeneration. Genistein, a flavonoid, has antioxidative properties to prevent neurodegeneration induced...
Gene expression suggests spontaneously hypertensive rats may have altered metabolism and reduced hypoxic tolerance [0.03%]
基因表达表明自发性高血压大鼠可能代谢异常且低氧耐受能力降低
Marie-Françoise Ritz,Caspar Grond-Ginsbach,Stefan Engelter et al.
Marie-Françoise Ritz et al.
Cerebral small vessel disease (SVD) is an important cause of stroke, cognitive decline and vascular dementia (VaD). It is associated with diffuse white matter abnormalities and small deep cerebral ischemic infarcts. The molecular mechanisms...
PDGF receptor β signaling in pericytes following ischemic brain injury [0.03%]
缺血性脑损伤后周细胞中PDGF受体β信号转导
Koichi Arimura,Tetsuro Ago,Masahiro Kamouchi et al.
Koichi Arimura et al.
Platelet derived growth factor (PDGF)-B plays a neuroprotective role in brain damages, including ischemic stroke. It has been suggested recently that PDGF receptor β (PDGFRβ) expressed in brain pericytes as well as in neurons and astrocyt...
Ryszard Pluta,Jukka Jolkkonen,Salvatore Cuzzocrea et al.
Ryszard Pluta et al.
Ischemic stroke is a leading cause of death and cognitive impairment worldwide. However, the mechanisms of progressive cognitive decline following brain ischemia are not yet certain. Ongoing interest in cerebrovascular diseases research has...