Transcriptomic Changes Associated with Electroacupuncture in a DMCAO Model of Delayed Cognitive Impairment [0.03%]
与电针法相关的转录组变化在DMCAO模型的迟发性认知障碍中的作用
Liyue Lu,Wei Song,Shichun Li et al.
Liyue Lu et al.
Introduction: Delayed Cognitive Impairment (DCIS) occurs in approximately 31% to 77% of individuals following stroke. Clinical findings have indicated that electroacupuncture may alleviate post-stroke DCIS. However, insig...
Design, Synthesis, and Evaluation of Voltage-gated Sodium Channel Inhibitors as Anticonvulsant Agents [0.03%]
设计、合成和评估电压门控钠通道抑制剂作为抗惊厥剂的研究
Preeti Kumari,Rakhi Mishra,Rupa Mazumder et al.
Preeti Kumari et al.
Introduction: The objective of this study is to explore the therapeutic potential of synthesized hetero fused acylurea derivatives by investigating their ability to bind with voltagegated sodium ion channel receptors, fol...
Aspartame and Neurotoxicity: Quantitative Insights from Biomarker and Dose-response Analysis [0.03%]
关于阿斯巴甜和神经毒性：来自生物标志物和剂量效应分析的定量见解
Arbind Kumar Choudhary,Nishant Singh
Arbind Kumar Choudhary
Introduction: Aspartame, a widely consumed artificial sweetener, raises concerns regarding its potential neurotoxic effects mediated through oxidative stress pathways. This systematic review and meta-analysis quantified t...
Intraoperative Diabetes Insipidus as a Predictor of Postoperative Complications Following Revascularization in Moyamoya Disease: A Retrospective Cohort Study [0.03%]
糖尿病 insipidus 判断 moyamoya 病变动静脉重建术术后并发症的作用：回顾性队列研究
Jia Lu,Qian Chen,Xin Zhang et al.
Jia Lu et al.
Background: Surgical revascularization represents an effective treatment for moyamoya disease (MMD); however, it is associated with postoperative complications such as stroke and hyperperfusion syndrome. Intraoperative po...
Lower Perioperative Complications of Stent Implantation Assisted by Intracranial Support Catheter in the Treatment of ICAS: A Single-center Experience [0.03%]
颅内支持管辅助支架植入治疗ICAS围手术期并发症更低：单中心经验
Yongtai Lin,Cong Li,Hao Xiao et al.
Yongtai Lin et al.
Introduction: Stent implantation is an important treatment for intracranial atherosclerotic stenosis (ICAS). However, excessive perioperative complications can diminish patient benefits. The use of appropriate instruments...
Bioinformatics Analysis of ZDHHC-protein Acyltransferase for Predicting the Rupture of Aneurysmal Subarachnoid Hemorrhage [0.03%]
ZDHHC蛋白酰基转移酶的生物信息学分析及其预测动脉瘤性蛛网膜下腔出血破裂的研究
Wanjing Zhang,Lu Liu,Yajun Hou et al.
Wanjing Zhang et al.
Introduction: Intracranial aneurysms (IAs) can cause life-threatening subarachnoid hemorrhage upon rupture, yet their molecular mechanisms remain poorly understood. Proteins encoded by the ZDHHC genes mediate protein palm...
Perioperative Liver Function Parameters as Potential Predictors of Hemorrhagic Transformation in Acute Ischemic Stroke Patients with Successful Recanalization after Endovascular Treatment: A Retrospective Cohort Study [0.03%]
成功取栓的急性缺血性卒中患者术前术后肝功能指标预测出血转化的回顾性队列研究
Kai Wang,Di Luan
Kai Wang
Introduction: Acute ischemic stroke (AIS) is a leading global cause of death/ disability; endovascular thrombectomy (EVT) treats large vessel occlusion, but postrecanalization hemorrhagic transformation (HT) raises mortal...
Blood-brain Barrier Dysfunction in Parkinson's Disease: Mechanisms and Emerging Therapeutic Strategies [0.03%]
帕金森病的血脑屏障功能障碍：机制和新兴治疗策略
Gursimran Singh,Khadga Raj Aran
Gursimran Singh
Introduction: PD is a progressive neurodegenerative disorder, which is associated with the deterioration of dopaminergic neurons in the substantia nigra pars compacta (SNpc), resulting in motor and non-motor symptoms. Pat...
Pathogen Antibodies and Parkinson's Disease: A Two-Sample Mendelian Randomization Study [0.03%]
病原体抗体与帕金森病：两样本孟德尔随机化研究
Yuyan Lu,Liang Zhou,Guirong Dong et al.
Yuyan Lu et al.
Introduction: Parkinson's disease (PD) is a prototypical neurodegenerative disease. Evidence suggests infection-induced immune responses contribute to the pathogenesis of PD; however, establishing causality from observati...
The Multifaceted Pathophysiology of Major Depressive Disorder: Integrating Neurobiology, Genetics, and Systems-level Perspectives [0.03%]
重大抑郁障碍的多方面病理生理学：整合神经生物学、遗传学和系统水平的观点
Satya Prakash,Deepika Bhatia
Satya Prakash
Introduction: Major Depressive Disorder (MDD) is a debilitating and multifactorial neuropsychiatric condition that significantly contributes to the global burden of disease. Its clinical spectrum encompasses persistent lo...