Low-dose tissue plasminogen activator is as effective as standard tissue plasminogen activator administration for the treatment of acute ischemic stroke [0.03%]
低剂量重组组织型纤溶酶原激活剂与标准剂量重组组织型纤溶酶原激活剂治疗急性缺血性卒中的疗效比较
Hui Chen,Guangming Zhu,Nan Liu et al.
Hui Chen et al.
We compared the efficacy of intravenous (IV) combination of low-dose tissue plasminogen activator (tPA) and urokinase (UK) versus either classical IV tPA or UK alone for acute ischemic stroke (AIS) within 4.5 h of symptom onset. One-hundred...
Age-related vascular differences among patients suffering from multiple sclerosis [0.03%]
多发性硬化患者中的年龄相关血管差异
Francesco Ciciarello,Sandro Mandolesi,Aldo Innocente Galeandro et al.
Francesco Ciciarello et al.
The aim of our study was to analyze morphological and functional aspects of cerebral veins by means of ecocolor-Doppler in young (i.e., ≤ 30 years old) and older (i.e., >30 years old) patients suffering from multiple sclerosis. 552 multipl...
Neurovascular changes in acute, sub-acute and chronic mouse models of Parkinson's disease [0.03%]
急性，亚急性和慢性帕金森病小鼠模型中的神经血管改变
Sumit Sarkar,James Raymick,Dushyant Mann et al.
Sumit Sarkar et al.
Although selective neurodegeneration of nigro-striatal dopaminergic neurons is widely accepted as a cause of Parkinson's disease (PD), the role of vascular components in the brain in PD pathology is not well understood. However, the neurode...
Systemic administration of fluoro-gold for the histological assessment of vascular structure, integrity and damage [0.03%]
氟化荧光素金的全身给药用于血管结构、完整性和损伤的组织学评估
John F Bowyer,Karen M Tranter,Sumit Sarkar et al.
John F Bowyer et al.
Fluoro-Gold (F-G) has been used extensively as a fluorescent retrograde neuronal-track tracer in the past. We now report that intraperitoneal administration of 10 to 30 mg/ kg of F-G from 30 min to 7 days prior to sacrifice labels vascular ...
Early cerebral infarction following aneurysmal subarachnoid hemorrhage: frequency, risk factors, patterns, and prognosis [0.03%]
动脉瘤性蛛网膜下腔出血后早期脑梗死的发病频率、危险因素、分布及预后研究
Chao Fu,Weidong Yu,Libo Sun et al.
Chao Fu et al.
Early cerebral infarction (ECI) following aneurysmal subarachnoid hemorrhage (aSAH) remains poorly understood. This study aims to determine the frequency and risk factors of this special episode, as well as to assess the relationship betwee...
Prolactin protects against the methamphetamine-induced cerebral vascular toxicity [0.03%]
泌乳素对甲基苯丙胺致脑血管毒性的保护作用
Hector Rosas-Hernandez,Elvis Cuevas,Susan M Lantz et al.
Hector Rosas-Hernandez et al.
Methamphetamine (Meth) is a highly addictive drug of abuse which alters the dopaminergic system and damages the blood-brain barrier (BBB), structure that protects the brain tissue from the circulating substances in the blood, keeping a low ...
Crosstalk between the angiotensin and endothelin-system in the cerebrovasculature [0.03%]
血管紧张素和内皮素系统在脑血管中的相互作用
Juergen Konczalla,Stefan Wanderer,Jan Mrosek et al.
Juergen Konczalla et al.
Investigations have shown a multifactorial process as cause for the poor outcome after subarachnoid hemorrhage (SAH), including inflammation, early brain injury, cortical spreading depression, lack of cerebral autoregulation and the cerebra...
Crocetin attenuates spatial learning dysfunction and hippocampal injury in a model of vascular dementia [0.03%]
藏红花黄素通过改善血管性痴呆大鼠模型空间学习记忆障碍及海马神经元损伤发挥作用
Faezeh Tashakori-Sabzevar,Hossein Hosseinzadeh,Vahideh Sadat Motamedshariaty et al.
Faezeh Tashakori-Sabzevar et al.
Chronic cerebral hypoperfusion produces brain ischemia and is associated with related memory impairment. In this study, we prepared crocetin from crocin (the main water soluble pigment in saffron stigmas) in an acidic hydrolysis and its pur...
Fluoxetine enhances Brain Derived Neurotropic Factor Serum Concentration and Cognition in Patients with Vascular Dementia [0.03%]
氟西汀可提高血管性痴呆患者的脑源性神经营养因子浓度和认知水平
Xuan Liu,Junjian Zhang,Dong Sun et al.
Xuan Liu et al.
Selective serotonin reuptake inhibitors (SSRIs) improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (BDNF) in the rat hippocampus. However, the effects of SSRIs on cognition and BDNF le...