Reduction in ischemic cerebral infarction is mediated through golgi phosphoprotein 3 and Akt/mTOR signaling following salvianolate administration [0.03%]
丹参酚酸通过高尔基蛋白3和Akt/mTOR信号减轻缺血性脑梗死
Hong You,Ting Li,Jinnan Zhang et al.
Hong You et al.
Salvianolate has been reported to possess protective properties. However, its specific mechanisms have yet to be identified. Our study aimed to identify the molecular mechanism of antioxidative stress function of salvianolate on rat ischemi...
Status epilepticus in the immature rodent brain alters the dynamics of autophagy [0.03%]
早发性癫痫持续状态会改变自噬动力学
Alexander Philipp Benz,Jerôme Niquet,Claude Guy Wasterlain et al.
Alexander Philipp Benz et al.
There is considerable interest in defining the molecular pathways involved in seizure-induced neuronal death. Necrotic, apoptotic and anti-apoptotic signalling pathways are activated after status epilepticus (SE). Analyses of apoptosis and ...
Modulation of transient receptor potential vanilloid subtype 1 (TRPV1) and norepinephrine transporters (NET) protect against oxidative stress, cellular injury, and vascular dementia [0.03%]
瞬时受体电位香草素亚型1（TRPV1）和去甲肾上腺素转运蛋白（NET）的调节对氧化应激、细胞损伤和血管性痴呆具有保护作用
Surbhi Gupta,Bhupesh Sharma,Prabhat Singh et al.
Surbhi Gupta et al.
Chronic cerebral hypoperfusion (CCH) is a risk factor for the development of vascular dementia (VaD). CCH participates in a negative role in cognitive impairments. Transient receptor potential vanilloid subtype 1 (TRPV1) participates in cog...
Epigenetics in the cerebrovascular system: changing the code without altering the sequence [0.03%]
脑血管系统的表观遗传学：不改变序列而改变代码
Kenneth Maiese
Kenneth Maiese
Sepsis in the central nervous system and antioxidant strategies with N-acetylcysteine, vitamins and statins [0.03%]
用N-乙酰半胱氨酸、维生素和他汀类药物抗氧化策略治疗中枢神经系统的脓毒症
Amanda Valnier Steckert,Adalberto Alves de Castro,Joao Quevedo et al.
Amanda Valnier Steckert et al.
Sepsis is the complex syndrome characterized by an imbalance between proinflammatory and antiinflammatory response to infection. The brain may be affected during the sepsis, and acute and long-term brain dysfunctions have been observed in b...
Characterization of Lin-ve CD34 and CD117 cell population reveals an increased expression in bone marrow derived stem cells [0.03%]
Lin-阴性CD34和CD117细胞群的特征表明其在骨髓源干细胞中的表达增加
Neeru Jindal,Gillipsie Minhas,Sudesh Prabhakar et al.
Neeru Jindal et al.
The purpose of the study was to evaluate the expression of CD45, CD34, Sca-1 and CD117 in mouse bone marrow, Lin-ve and Lin+ve population. Bone marrow cells were isolated from C57/BL6J mouse and mononuclear population was separated from res...
Flow volumes of internal jugular veins are significantly reduced in patients with cerebral venous sinus thrombosis [0.03%]
颅内静脉窦血栓患者颈内静脉流量明显减少
Özkan Özen,Özkan Ünal,Serhat Avcu
Özkan Özen
The aim of this study was to investigate the flow volumes of the internal jugular veins (IJVs) in patients with cerebral venous sinus thrombosis (CVST) using Doppler ultrasonography (DUS) and to compare the findings with the control group. ...
Early timing of endovascular treatment for aneurysmal subarachnoid hemorrhage achieves improved outcomes [0.03%]
早期进行血管内治疗可改善动脉瘤性蛛网膜下腔出血预后
Zenghui Qian,Tangming Peng,Aihua Liu et al.
Zenghui Qian et al.
Timing of treatment of aneurysmal subarachnoid hemorrhage has been controversial. This retrospective study was designed to access the safety and efficacy among cohorts of different timing of endovascular treatment patients with aneurysmal s...
LINE-1 methylation is associated with an increased risk of ischemic stroke in men [0.03%]
LINE-1甲基化程度与男性缺血性卒中发病风险增加有关
Reuy-Tay Lin,Edward Hsi,Hsiu-Fen Lin et al.
Reuy-Tay Lin et al.
The level of global DNA methylation may be related to the cerebrovascular disease. The methylation level of Long Interspersed Nucleotide Element 1 (LINE-1) can represent the global methylation level. We investigated the association between ...
Genetic polymorphism of LDLR (rs688) is associated with primary intracerebral hemorrhage [0.03%]
LDLR基因多态性与自发性脑出血的关系研究
Jiann-Der Lee,Kuang-Ming Hsiao,Tsong-Hai Lee et al.
Jiann-Der Lee et al.
Intracranial hemorrhage is the third most common cause of cerebrovascular disease. Some polymorphisms that affect clotting factors increase the risk of thrombosis. However, few reports have analyzed the effect of polymorphisms on the hemost...