Safety and Efficacy of Dual Antiplatelet versus Single Antiplatelet Therapy after Intravenous Thrombolysis for Acute Ischemic Stroke [0.03%]
静脉溶栓治疗急性缺血性卒中后双联抗血小板与单用抗血小板治疗的有效性和安全性：一项系统综述和 meta 分析研究
Wenli Song,Zhimin Yu,Tiaming Shi et al.
Wenli Song et al.
Objective: This study evaluates the safety and efficacy of Dual Antiplatelet Therapy (DAPT) compared to Single Antiplatelet Therapy (SAPT) in Acute Ischemic Stroke (AIS) patients treated with Intravenous Thrombolysis (IVT...
Mendelian Randomization Analysis of Different Cathepsin Isoforms Associated with Neurodegenerative Diseases [0.03%]
不同组织蛋白酶与神经退行性疾病相关的梅德利随机化分析
Fei Yang,XinYu Shi,YiNi Wang et al.
Fei Yang et al.
Introduction: Recent studies indicate that cathepsins play an important role in neurodegenerative diseases. However, further exploration is required to determine the association between each isoform of cathepsin and disea...
Synergistic Anti-dementia Effects of Symplocos racemosa Nanoemulsion: Isolation, Molecular Docking, and In Vivo Evaluation [0.03%]
symplocos racemosa 纳米乳的协同抗痴呆功效：分离、分子对接和体内评价
Archna Singh,Avijit Mazumder,Saumya Das et al.
Archna Singh et al.
Introduction: Dementia, marked by a decline in mental abilities like memory that interferes with daily life, is primarily caused by Alzheimer's Disease (AD). Symplocos racemosa, rich in acetyl oleanolic acid, serves as a ...
Neurosyphilis and Parkinsonism: Overlapping Pathophysiology and Emerging Therapeutic Insights [0.03%]
神经梅毒和帕金森氏症：病理生理的重叠及新兴治疗见解
Shruti,Zuber Khan,Mustak Ahamed et al.
Shruti et al.
Introduction: Neurosyphilis, caused by Treponema pallidum, is a complex neurological condition arising from untreated syphilis and can present with diverse manifestations, including Parkinsonism-like motor dysfunction. It...
Preparation and Characterization of Insulin-loaded Polymeric Nanoparticles for Nasal Delivery [0.03%]
鼻粘膜给药胰岛素载药聚合物纳米粒的制备及表征
Darshna Mishra,Shikha Yadav
Darshna Mishra
Introduction: Intranasal delivery of insulin offers a promising non-invasive route to target the brain, particularly for neurodegenerative disorders like Alzheimer's disease (AD). However, challenges such as enzymatic deg...
Multimodal MRI Combined with Cognitive Evaluation Reveals Glymphatic System Impairment in Moyamoya Vasculopathy [0.03%]
多模态磁共振成像结合认知评估揭示 Moyamoya 病患者甘淋巴系统功能障碍
Shuo Shao,Huimin Huang,Ning Zheng et al.
Shuo Shao et al.
Introduction: The aim of this research is to fully assess glymphatic system impairment in moyamoya vasculopathy (MMV) patients with a set of multi-modal MRI biomarkers that capture crucial functional processes: cerebrospi...
Molecular Pathways of Microbiota-derived Neuromodulation: An Integrative View [0.03%]
整合视角下的微生物群源性神经调制分子途径
Supreet Kaur,Nishtha Bhandari,Shushank Mahajan et al.
Supreet Kaur et al.
Introduction: The gut microbiota, also called "the forgotten organ", is a complex and dynamic ecosystem of microorganisms that is fundamental to human physiology, neurobiology, and disease. This review examines the intric...
The Potential Molecular Mechanisms and Key Genes of Early Deterioration of Parenchymal Lesions in Cerebral Venous Sinus Thrombosis [0.03%]
关于颅内静脉窦血栓形成脑梗死早期坏死灶恶化的分子机制及关键基因研究
Gengyu Cen,Jiaxin Li,Jun Wang et al.
Gengyu Cen et al.
Introduction: Cerebral Venous Sinus Thrombosis (CVST) is a disease with a low incidence rate but is prone to progression and Early Deterioration of Parenchymal Lesions (EDPL), leading to severe neurological impairment. Ex...
Prognostic factors for in-stent restenosis after cerebrovascular stent implantation among ischemic stroke patients. [0.03%]
缺血性卒中患者颅内支架植入术后再狭窄的预后因素分析
Shiliang Xia,JIaxing You,Delong Wang et al.
Shiliang Xia et al.
Background: Cerebrovascular stent implantation is an established treatment for revascularization, but the benefits of cerebrovascular stent implantation are highly affected by the incidence of in-stent restenosis. We aime...
Riku Ohwada,Toshio Imaizumi,Kyoya Sakashita et al.
Riku Ohwada et al.
Introduction: Lacunar infarction (LI) and enlarged perivascular spaces (EPVSs) are key MRI findings in cerebral small vessel disease. The underlying causes of LI and EPVS share similarities. To explore their relationship,...