Plasma Level of D-dimer is an Independent Diagnostic Biomarker for Deep Venous Thrombosis in Patients with Ischemic Stroke [0.03%]
D-二聚体血浆水平是缺血性卒中患者深静脉血栓独立诊断标志物
Xiang-li Kong,Xiang Zhang,Shi-jun Zhang et al.
Xiang-li Kong et al.
This study was to determine the clinical diagnostic value of D-dimer for DVT in patients with ischemic stroke. During July 2013 to December 2014, a cohort study of ischemic stroke patients who presented with symptoms of DVT in upper or lowe...
Long Non-coding RNA HOTAIR Promotes Parkinson's Disease Induced by MPTP Through up-regulating the Expression of LRRK2 [0.03%]
长非编码RNA HOTAIR通过上调LRRK2的表达促进MPTP诱导的帕金森病
Sen Liu,Bei Cui,Zhen-xia Dai et al.
Sen Liu et al.
Homeobox (HOX) transcript antisense RNA (HOTAIR), as a long intergenic noncoding RNA (lincRNA), is known to be overexpressed in several cancers. However, the role of HOTAIR in Parkinson's disease (PD) remains unclear. A mouse model of PD wa...
Adoptive Regulatory T-cell Therapy Attenuates Subarachnoid Hemor-rhage-induced Cerebral Inflammation by Suppressing TLR4/NF-B Signaling Pathway [0.03%]
适应性调节t细胞疗法通过抑制tlr4/nf-b信号途径减轻蛛网膜下腔出血所致脑炎症反应
Yuan Wang,Leilei Mao,Lei Zhang et al.
Yuan Wang et al.
Inflammation is one major cause of poor outcomes of subarachnoid hemorrhage (SAH). The recent evidence suggested that adoptive regulatory T-cell (Treg) therapy conferred potential neuroprotection by suppressing cerebral inflammation against...
Selective Serotonin-norepinephrine Re-uptake Inhibition Limits Renovas-cular-hypertension Induced Cognitive Impairment, Endothelial Dysfunction, and Oxidative Stress Injury [0.03%]
选择性血清素去甲肾上腺素再摄取抑制剂限制了血管高血压引起的认知障碍，内皮功能障碍和氧化应激损伤
Prabhat Singh,Bhupesh Sharma
Prabhat Singh
Hypertension has been reported to induce cognitive decline and dementia of vascular origin. Serotonin- norepinephrine reuptake transporters take part in the control of inflammation, cognitive functions, motivational acts and deterioration o...
Plasma Angiotensin-(1-7) is a Potential Biomarker for Alzheimer's Disease [0.03%]
血浆血管紧张素-（1-7）是阿尔茨海默病的潜在生物标志物
Teng Jiang,Lan Tan,Qing Gao et al.
Teng Jiang et al.
Brain angiotensin-(1-7) (Ang-(1-7)) concentration has been shown to be reduced and inversely correlated with tau pathology in a mouse model of Alzheimer's disease (AD). In this study, to determine whether the concentration of Ang-(1-7) and ...
Modeling Loss of Microvascular Wall Homeostasis during Glycocalyx Deterioration and Hypertension that Impacts Plasma Filtration and Solute Exchange [0.03%]
糖萼退化和高血压影响下模拟微血管内皮细胞稳态丧失及其对血浆滤过和溶质交换的影响
Laura Facchini,Alberto Bellin,Eleuterio Francisco Toro
Laura Facchini
The fiber matrix of the surface glycocalyx layer internally coating the endothelial cells and plugging the intercellular clefts is crucial for microvascular wall homeostasis. Disruption of the glycocalyx is found in clinical conditions char...
Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage Score For Predicting Outcome [0.03%]
预测脑出血结果的CAAICH评分
Chunyan Lei,Bo Wu,Ming Liu et al.
Chunyan Lei et al.
The existing intracerebral hemorrhage (ICH) scores were based on the clinical and anatomical parameters of all primary ICH. We aimed to study whether the original ICH Score can predict cerebral amyloid angiopathy (CAA)-related ICH mortality...
Antioxidant Therapy Alters Brain MAPK-JNK and BDNF Signaling Path-ways in Experimental Diabetes Mellitus [0.03%]
抗氧化治疗可改变糖尿病动物模型脑内MAPK-JNK和BDNF信号通路
Gislaine Zilli Réus,Maria Augusta Bernardini Dos Santos,Helena Mendes Abelaira et al.
Gislaine Zilli Réus et al.
This study was designed to investigate the effects of treatment with the antioxidants N-acetylcysteine (NAC) and deferoxamine (DFX) in intracellular pathways in the brain of diabetic rats. To conduct this study we induced diabetes in Wistar...
Vinicius Sousa Pietra Pedroso,Milene Alvarenga Rachid,Antonio Lucio Teixeira
Vinicius Sousa Pietra Pedroso
Depression is the most frequent neuropsychiatric complication after a stroke. Post-stroke depression has a significant impact on the outcome and prognosis of affected patients. Its diagnosis is complex and currently based only on clinical p...