Overexpression of MiR-188-5p Downregulates IL6ST/STAT3/NLRP3 Pathway to Ameliorate Neuron Injury in Oxygen-glucose Deprivation/Reoxygenation [0.03%]
MiR-188-5p过表达通过下调IL6ST/STAT3/NLRP3通路改善氧糖剥夺再灌注小鼠神经元损伤
Guoshuai Yang,Yujie Hu,Ganlan Wang
Guoshuai Yang
Background: CI/R, characterized by ischemic injury following abrupt reestablishment of blood flow, can cause oxidative stress, mitochondrial dysfunction, and apoptosis. We used oxygen-glucose deprivation/reoxygenation (OG...
A Study on the Effects of Different Positions on the Clinical Prognosis of Patients with Acute Ischemic Stroke [0.03%]
不同体位对急性缺血性卒中患者临床预后影响的研究
Qinqin Dai,Mengmeng Zhang,Yuanli Guo et al.
Qinqin Dai et al.
The key to treating Acute Ischemic Stroke (AIS) is to rapidly reopen occluded blood vessels, restore blood flow, and rescue the ischemic penumbra. Treatment methods mainly include thrombolysis, endovascular intervention, etc. However, these...
Nomogram to Predict 90-Day All-Cause Mortality in Acute Ischemic Stroke Patients after Endovascular Thrombectomy [0.03%]
急性缺血性卒中患者血管内机械取栓术后的90天全因死亡预测列线图
Shiya Zhang,Shuai Yu,Xiaocui Wang et al.
Shiya Zhang et al.
Objective: Although Endovascular Thrombectomy (EVT) significantly improves the prognosis of Acute Ischemic Stroke (AIS) patients with large vessel occlusion, the mortality rate remains higher. This study aimed to construc...
Electroacupuncture Inhibits Neural Ferroptosis in Rat Model of Traumatic Brain Injury via Activating System Xc-/GSH/GPX4 Axis [0.03%]
电针通过激活系统Xc- / GSH / GPX4轴抑制脑外伤大鼠模型的神经铁死亡
Na Li,Ruihui Wang,Xia Ai et al.
Na Li et al.
Background: Ferroptosis is an iron-dependent regulating programmed cell death discovered recently that has been receiving much attention in traumatic brain injury (TBI). xCT, a major functional subunit of Cystine/glutamic...
Extract of Gualou-Xiebai Herb Pair Improves Lipid Metabolism Disorders by Enhancing the Reverse Cholesterol Transport in Atherosclerosis Mice [0.03%]
瓜蒌薤白提取物通过改善动脉粥样硬化小鼠胆固醇逆向转运防治脂代谢紊乱
Yarong Liu,Tian Wang,Lidan Ding et al.
Yarong Liu et al.
Background: Gualou is derived from the fruit of Trichosanthes kirilowii Maxim, while Xiebai from the bulbs of Allium macrostemon Bunge. Gualou and Xiebai herb pair (2:1) is widely used in clinical practice to treat athero...
Comparison of 4 mm-sized and 3 mm-sized Stent Retrievers in Mechanical Thrombectomy for M2 Occlusion [0.03%]
比较不同尺寸的支架取栓器治疗M2段闭塞的效果
Han Gyul Lee,Ho Jun Yi,Dong-Seong Shin et al.
Han Gyul Lee et al.
Introduction: A stent retriever (SR) is widely used in mechanical thrombectomy (MT) for M2 segment occlusion. However, the suitable size of SR in M2 occlusion remains unclear. Therefore, we aimed to compare 4 mm-sized SR ...
Neuroimaging Marker-CT Perfusion of Early Neurological Deterioration in Patients with Minor Stroke and Large Vessel Occlusion after Intravenous Thrombolysis [0.03%]
急性轻型卒中大血管闭塞患者静脉溶栓后早期神经功能恶化的影像学生物标志物：脑灌注CT研究
Hongli Zhang,Wanli Bao,Meiyan Yu et al.
Hongli Zhang et al.
Objective: Early Neurological Deterioration (END) is one of the complications in Acute ischemic stroke (AIS) and relates to prognosis. However, the reason why it occurs is still unclear. Our study is to investigate if CT ...
Analysis of the Relationship between Recent Small Subcortical Infarcts and Autonomic Nervous Dysfunction [0.03%]
近期小缺血灶与自主神经功能损害关系的分析
Wenxin Yuan,Lu An,Yunchao Wang et al.
Wenxin Yuan et al.
Objective: Autonomic Nervous System (ANS) dysfunction may be involved in the pathogenesis of Cerebral Small Vessel Disease (CSVD). The study aimed to explore the relationship between Recent Small Subcortical Infarct (RSSI...
Cerebral Small Vessel Disease Burden in Patients with Transient Global Amnesia and its Relationship with Recurrence [0.03%]
短暂性全球性遗忘症患者的脑小血管病负担及其与复发的关系
Zhi-Li Wang,Simeng Wang,Dongtao Liu et al.
Zhi-Li Wang et al.
Objective: Cerebral Small Vessel Disease (CSVD) has not been systematically studied in patients with Transient Global Amnesia (TGA). We aimed to investigate the CSVD burden in patients with TGA and its relationship with T...
Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease [0.03%]
孟德尔随机化研究突显短链脂肪酸产生者肠道微生态在脑血管疾病中的保护作用
Shihang Luo,Rui Mao,Yi Li
Shihang Luo
Background: Recent research advancements have indicated a potential association between gut microbiota and cerebrovascular diseases, although the precise causative pathways and the directionality of this association remai...