Constipation Increases Disability and Decreases Dopamine Levels in the Nigrostriatal System through Gastric Inflammatory Factors in Parkinson's Disease [0.03%]
便秘通过胃炎性因子在帕金森病中增加残疾并减少黑质纹状体系统中的多巴胺水平
Yongtao Zhou,Yusheng Su,Weihua Xu et al.
Yongtao Zhou et al.
Objective: Recent studies suggest that not only is constipation a clinical marker of premotor phase in Parkinson's Disease (PD), but is also correlated with the duration and severity. Some reports indicated that inflammat...
Anti-VEGFR2 Antibody-modified Micelle for Triggered Drug Delivery and Effective Therapy of Choroidal Neovascularization [0.03%]
针对脉络膜新生血管的刺激型药物递送抗VEGFR2抗体修饰的胶束及其有效治疗作用研究
Kei Takahashi,Tomomi Masuda,Mitsunori Harada et al.
Kei Takahashi et al.
Objective: This study aimed to examine whether DC101 (anti-VEGFR2 antibody)- modified micelles have applications as novel drug delivery devices, which allow small molecule antiangiogenic agents to deliver to angiogenic si...
A Potential Role for the Existence of Pericytes in the Neurovascular Unit of the Sexually Dimorphic Nucleus of the Rat Preoptic Area to Control Blood-Brain Barrier Function [0.03%]
关于性染色体不同的前脑区神经血管单位中存在的周细胞在控制血脑屏障功能中的潜在作用角色分析报告
Zhen He,Tucker A Patterson
Zhen He
Background: The present study aimed at determining pericytes, a missing component in the previously proposed living neurovascular unit (NVU) of the sexually dimorphic nucleus of the preoptic area (SDN-POA) in rats. ...
Impact of Collateral Status on Neuroprotective Effect of Cyclosporine A in Acute Ischemic Stroke [0.03%]
缺血性卒中不同时间窗内CsA神经保护作用及担保机制研究
Norbert Nighoghossian,Lucie Cornut,Camille Amaz et al.
Norbert Nighoghossian et al.
Background: Neuroprotection for acute ischemic stroke remains an elusive goal. Intracranial collaterals may favor neuroprotective drugs delivery at the acute stage of ischemic stroke. A recent phase 2 study showed that cy...
Sodium Hydrosulfide Post-conditioning Protects Hippocampal CA1 Neurons from Neuronal Cell Injury in the Rat Model of Transient Global Cerebral Ischemia Through Activation of Extracellular-regulated Kinases Signaling [0.03%]
硫化氢通过激活细胞外信号调节激酶信号通路在全脑缺血再灌注损伤中的神经保护作用
ChengPing Bai,ChenLiang Zhao
ChengPing Bai
Introduction: The effect of hydrogen sulfide (H2S) on global cerebral ischemia remains partially understood. This study aimed to investigate the neuroprotective effect of sodium hydrosulfide (NaHS, a donor of H2S) post-co...
Analysis of the Clinical Characteristics and Follow-up Study of Children with Cutaneous Polyarteritis Nodosa [0.03%]
儿童皮肤多动脉炎的临床分析及随访研究
Qiang He,Jing Shu,Fang Chen et al.
Qiang He et al.
Objective: This study aims to analyze the clinical characteristics, treatment and prognosis of children with cutaneous polyarteritis nodosa (CPAN), in order to improve the understanding of this disease. ...
Artificial Hibernation by Phenothiazines: A Potential Neuroprotective Therapy Against Cerebral Inflammation in Stroke [0.03%]
苯并噻嗪类药物诱导的假冬眠：中风继发脑炎症神经保护治疗的新策略
Longfei Guan,Sichao Guo,James Yip et al.
Longfei Guan et al.
Background: The inflammatory response to acute cerebral ischemia is a major factor in stroke pathobiology and patient outcome. In the clinical setting, no effective pharmacologic treatments are currently available. Phenot...
Patterns of Acute Intracranial Hemorrhage in Adult Patients with Bilateral and Unilateral Moyamoya Disease [0.03%]
moyamoya病成人患者的急性脑内出血模式分析
Zhiyuan Yu,Jun Zheng,Rui Guo et al.
Zhiyuan Yu et al.
Background: Moyamoya disease (MMD) is a rare cerebrovascular disease. The difference of hemorrhagic patterns in adult patients with bilateral and unilateral MMD is still unclear. ...
Comparative Study
Current neurovascular research. 2019;16(3):202-207. DOI:10.2174/1567202616666190621093652 2019
Decrease in Secondary Neck Vessels in Multiple Sclerosis: A 5-year Longitudinal Magnetic Resonance Angiography Study [0.03%]
多发性硬化患者继发性颈动脉血管改变的纵向研究
Dejan Jakimovski,Matthew Topolski,Kana Kimura et al.
Dejan Jakimovski et al.
Background: Studies have previously shown greater arterial and venous extracranial vascular changes in persons with multiple sclerosis (PwMS) when compared to healthy controls (HCs). ...
A Direct Correlation between Red Blood Cell Indices and Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage (aSAH) [0.03%]
动脉瘤性蛛网膜下腔出血(aSAH)后认知障碍与红细胞指数直接相关性研究
Li Gong,Yongzhe Gu,Qiong Dong et al.
Li Gong et al.
Background: Cognitive impairment can occur after aneurysmal subarachnoid hemorrhage (aSAH) though it commonly tends to be neglected. Red blood cell (RBC) indices are associated with long-term functional outcomes, while it...