Safety and Efficacy of Intra-arterial Tirofiban Injection During Mechanical Thrombectomy for Large Artery Occlusion [0.03%]
用于机械取栓治疗大动脉闭塞的动脉内替罗非班注射的安全性和有效性研究
Ho J Yi,Jae H Sung,Dong H Lee
Ho J Yi
Objective: The safety and effect of intra-arterial (IA) tirofiban, a glycoprotein IIb/IIIa inhibitor, during the stent retriever mechanical thrombectomy (MT) was investigated. ...
Role of Granulocyte-colony Stimulating Factor in the Protection of Cerebral Vascular Endothelium, White Matter, and Cognition [0.03%]
粒细胞集落刺激因子在脑血管内皮、白质和认知保护中的作用
Minghui Tuo,Yunyue Xiao,Yan Xu et al.
Minghui Tuo et al.
Background: Granulocyte-colony stimulating factor (G-CSF) has protective effects on many neurological diseases. The effects of G-CSF on vascular endothelium and White Matter (WM) injury in Cerebral Small Vessel Disease (C...
Curcumin Prevents Brain Damage and Cognitive Dysfunction During Ischemic-reperfusion Through the Regulation of miR-7-5p [0.03%]
姜黄素通过调节miR-7-5p预防缺血再灌注导致的脑损伤和认知障碍
Hui Xu,Beibei Nie,Lamei Liu et al.
Hui Xu et al.
Objective: This study was to investigate the potential protective effects of curcumin in cerebral ischemia-reperfusion (CIR) and its regulation of miR-7. ...
Association of Common Variants in the IL-33/ST2 Axis with Ischemic Stroke [0.03%]
血管性卒中与IL-33/ST2轴多态性的相关性研究
Shuo Li,Zhijie Wang,Xinjing Liu et al.
Shuo Li et al.
Background: Recent studies have reported that the levels of serum interleukin-33 (IL- 33) and its receptor, suppression of tumorigenicity 2 (ST2), are potential biomarkers for susceptibility of cardiovascular diseases. Ho...
Targeting Hypertension: Superoxide Anions are Involved in Apelininduced Long-term High Blood Pressure and Sympathetic Activity in the Paraventricular Nucleus [0.03%]
靶向高血压：超氧阴离子参与了阿皮林诱导的室旁核长期高血压和交感神经活性
Mingyue Ji,Qian Wang,Yuewu Zhao et al.
Mingyue Ji et al.
Aim: To determine whether apelin in paraventricular nucleus (PVN) can be a therapeutic target for hypertension. Background: Apelin is a...
Combined Transcriptomic and Proteomic Analyses of Cerebral Frontal Lobe Tissue Identified RNA Metabolism Dysregulation as One Potential Pathogenic Mechanism in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) [0.03%]
结合转录组和蛋白质组分析识别中枢神经系统遗传病CADASIL中潜在的致病机制——RNA代谢失调
Marie-Françoise Ritz,Paul Jenoe,Leo Bonati et al.
Marie-Françoise Ritz et al.
Background: Cerebral small vessel disease (SVD) is an important cause of stroke and vascular cognitive impairment (VCI), leading to subcortical ischemic vascular dementia. As a hereditary form of SVD with early onset, cer...
Radial Glia-endothelial Cells' Bidirectional Interactions Control Vascular Maturation and Astrocyte Differentiation: Impact for Blood-brain Barrier Formation [0.03%]
放射状脉管细胞与血管内皮细胞的双向交互控制血管成熟和星形胶质细胞分化：对血脑屏障形成的影响
Siqueira M da Silva,Gisbert D Campos,Flávia C A Gomes et al.
Siqueira M da Silva et al.
Background: In the developing cerebral cortex, Radial Glia (RG) multipotent neural stem cell, among other functions, differentiate into astrocytes and serve as a scaffold for blood vessel development. After some time, blo...
Risk Factors and Metabolism of Different Brain Regions by Positron Emission Tomography in Parkinson Disease with Disabling Dyskinesia [0.03%]
正电子发射断层扫描测定帕金森病致残性异动症的风险因素及不同脑区代谢状况
Huan Wei,Yongtao Zhou,Junwu Zhao et al.
Huan Wei et al.
Objective: Dyskinesia is the most common motor complication in advanced Parkinson's Disease (PD) and has a severe impact on daily life. But the mechanism of dyskinesia is still poorly understood. This study aims to explor...
Erythropoietin Gene Polymorphism rs551238 is Associated with a Reduced Susceptibility to Brain Injury in Preterm Infants [0.03%]
促红细胞生成素基因多态性rs551238与早产儿脑损伤易感性的降低有关
Ji Xu,Huitao Li,Jinjie Huang et al.
Ji Xu et al.
Background: Single Nucleotide Polymorphisms (SNPs) in the Erythropoietin (EPO) promoter region have been shown to influence EPO protein expression, and high blood levels of EPO are associated with an increased risk of bra...