Interpretable Machine Learning to Predict Anxiety or Depression in Acute Ischemic Stroke after IV Thrombolysis: A Retrospective Cohort Study [0.03%]
基于机器学习预测静脉溶栓取栓的急性缺血性卒中患者焦虑和抑郁症状：回顾性队列研究
Wenhui Shao,Cong Tian,Anqing Dong et al.
Wenhui Shao et al.
Background: Acute Ischemic Stroke (AIS) represents a prevalent cerebrovascular condition characterized by significant levels of disability and mortality. This study aimed to develop and validate a Machine Learning (ML) mo...
Interplay of Genetic and Biomarker Signatures in Oxidative Stress and Inflammation: Advancing Parkinson's Disease Research Through Emerging Omics Technologies [0.03%]
遗传和生物标志物特征在氧化应激和炎症中的相互作用：通过新兴组学技术推进帕金森病研究
Himangi Vig,Anuradha Mishra,Ankita Wal
Himangi Vig
Background: Parkinson's disease (PD) is a progressive neurodegenerative illness characterized by loss of dopaminergic neurons and misfolded α-synuclein aggregation. The pathophysiology of PD involves the interplay of oxi...
Gongda Li,Zhongyu Liu,Wenwen Li et al.
Gongda Li et al.
Introduction: Stroke is a leading cause of death and disability in adults globally, with its associated health burden rising steadily over recent decades. This review aims to systematically summarize the diverse cell type...
Admission-measured C-reactive Protein-to-albumin Ratio as a Predictive Marker for Hospital-acquired Infections in Patients with Spontaneous Intracerebral Hemorrhage [0.03%]
入院时测量的C反应蛋白-白蛋白比率可作为自发性脑出血患者医院获得性感染的预测标志物
Yikang Ouyang,Taotao Dong,Sen Zhang et al.
Yikang Ouyang et al.
Introduction: Spontaneous Intracerebral Hemorrhage (ICH) is associated with a high risk of Hospital-Acquired Infections (HAIs), contributing to poor neurological outcomes and increased healthcare burden. Early identificat...
FABP4 as a Key Target of Hederagenin in Ischemic Stroke: A Study Based on Network Pharmacology and Experimental Validation [0.03%]
基于网络药理学和实验验证的Hederagenin治疗缺血性脑卒中的关键靶点FABP4研究
Linglu Dun,Qian Yang,Wenhui Qin et al.
Linglu Dun et al.
Introduction: Ischemic Stroke (IS) shows high rates of mortality and disability, with a rising incidence. Persicae Semen (TaoRen), a traditional Chinese medicine, is known to promote blood circulation and resolve stasis. ...
Meta-analysis of Early Risk Factors Associated with Cerebrovascular Diseases [0.03%]
脑血管疾病早期危险因素的 meta 分析研究
Sanam Preet Kour,Himanshu Joshi,Ratnakar Shukla et al.
Sanam Preet Kour et al.
Introduction: Cerebrovascular diseases primarily affect the blood vessels in the brain and often result in life-threatening complications such as stroke. Several modifiable and non-modifiable risk factors contribute signi...
Prognostic Value of NT-proBNP and Left Atrial Diameter for Atrial Fibrillation in the Chronic Phase of Cryptogenic Stroke [0.03%]
慢性隐源性卒中患者NT-proBNP和左心房内径对房颤的预测价值
Yıldız Arslan,Ece Kavas,Yeliz Çiftçi et al.
Yıldız Arslan et al.
Introduction: This study investigated whether N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels and left atrial diameter (LAD) serve as reliable prognostic markers for the development of previously undetermined...
Investigating the Genetic and Inflammatory Mechanisms Behind Moyamoya Disease: A Literature Review [0.03%]
moyamoya病的遗传和炎症机制研究：文献综述
Ananth Kashibhatla,Idiberto José Zotarelli-Filho,Sanjeev Sreenivasan et al.
Ananth Kashibhatla et al.
Introduction: While a plethora of studies exist exploring the diverse components of MMD, a multifaceted approach is needed to target new therapeutic interventions and provide a holistic understanding of the genetic and in...
Development, Optimization, and Characterization of Donepezil Hydrochloride-loaded Emulsomes with Nigella Sativa Oil for the Treatment of Alzheimer's Disease [0.03%]
用于治疗阿尔茨海默病的氢溴酸多萘哌齐载脂乳粒的开发、优化与表征（以胡椒草油为载体）
Indu Singh,Meghna Dheek,Aiman Usmani et al.
Indu Singh et al.
Introduction: Alzheimer's disease is a progressive neurodegenerative disorder where conventional oral delivery of donepezil hydrochloride is limited by poor bioavailability and restricted brain access due to the blood-bra...
Electroacupuncture Alleviates Ischemic Stroke by Promoting Angiogenesis via m6A-mediated miR-214-3p/EZH2/eNOS Pathway [0.03%]
通过mRNA第六位腺苷酸修饰调控的miR-214-3p/EZH2/eNOS信号通路促进血管新生治疗脑缺血模型大鼠
Shizhen Song,Xinyao Ju,Tingting Zhang et al.
Shizhen Song et al.
Objective: This study aims to investigate the role of FTO-mediated m6A modification in the promotion of angiogenesis by electroacupuncture (EA) after ischemic stroke via the miR-214/EZH2/eNOS signaling axis. ...