Protective Effect of GSK-3β/Nrf2 Mediated by Dimethyl Fumarate in Middle Cerebral Artery Embolization Reperfusion Rat Model [0.03%]
马来酸二甲酯通过GSK-3β/Nrf2途径对大脑中动脉栓塞再灌注大鼠模型的保护作用
Yuan Li,Lan Chu,Chunfeng Liu et al.
Yuan Li et al.
Aim: This study investigated the protective effect of dimethyl fumarate (DMF) in rats by mediating glycogen synthase kinase 3β (GSK-3β)/Nrf2 using the middle cerebral artery embolization reperfusion (MCAO/R) rat model. ...
Hydroxysafflor Yellow a Promotes Angiogenesis in Rat Brain Microvascular Endothelial Cells Injured by Oxygen-glucose Deprivation/reoxygenation(OGD/R) through SIRT1-HIF-1α-VEGFA Signaling Pathway [0.03%]
羟基红花黄色素A通过SIRT1-HIF-1α-VEGFA信号通路促进氧糖剥夺/复氧损伤的大鼠脑微血管内皮细胞的血管生成
Juxuan Ruan,Lei Wang,Jiheng Dai et al.
Juxuan Ruan et al.
Objective: Angiogenesis led by brain microvascular endothelial cells (BMECs) contributes to the remission of brain injury after brain ischemia reperfusion. In this study, we investigated the effects of hydroxysafflor yell...
Point of Care Test Technology Suitable for Early Detection and Monitoring of Ischemic Stroke [0.03%]
适用于缺血性中风早期检测和监测的即时检验技术
Young Mi Lee,Mi Jung Bae,Ye Seul Choi et al.
Young Mi Lee et al.
Background: Stroke is one of the leading causes of death and disability in adulthood worldwide. A simple and convenient diagnostic method is needed for monitoring high-risk patients for stroke. Few POCTs are available for...
Interleukin-6: Important Mediator of Vasospasm Following Subarachnoid Hemorrhage [0.03%]
脑出血后血管痉挛的重要介质：白介素-6
Brandon Lucke-Wold,Koji Hosaka,William Dodd et al.
Brandon Lucke-Wold et al.
The correlation of neuroinflammation with the development of cerebral vasospasm following subarachnoid hemorrhage has been well documented in the literature; both clinical and preclinical. The exact mechanisms by which this process occurs, ...
Decoding the Transcriptional Response to Ischemic Stroke in Obese and Non-obese Mice Brain [0.03%]
肥胖和非肥胖小鼠脑对缺血性中风的转录反应解码
Jing Liang,Ruiyao Hu,Xin Wang et al.
Jing Liang et al.
Background: Ischemic Stroke (IS) is a serious cerebrovascular disease, which leads to irreversible damage or death of brain cells. Effective control of stroke risk factors can effectively reduce the incidence of IS. Howev...
Association Between Cardiometabolic Index and Stroke: A Population- based Cross-sectional Study [0.03%]
心代谢指数与卒中的关联性：基于人群的横断面研究
Feng-E Li,Yun Luo,Fu-Liang Zhang et al.
Feng-E Li et al.
Background: Cardiometabolic Index (CMI) was associated with several risk factors for stroke; however, few studies assessed the role of CMI in stroke risk. ...
Human Olfactory Ensheathing Cell-derived Extracellular Cesicles: miRNA Profile and Neuroprotective Effect [0.03%]
人嗅鞘细胞源性胞外囊泡：miRNA谱和神经保护作用
Yuan-Kun Tu,Yu-Huan Hsueh,Hsien-Chang Huang
Yuan-Kun Tu
Background: Extracellular Vesicle (EV)-based therapy has been identified as a leading alternative approach in several disease models. EV derived from the Olfactory Ensheathing Cell (OEC) has been documented for its strong...
A Non-Peptidic MAS1 Agonist AVE0991 Alleviates Hippocampal Synaptic Degeneration in Rats with Chronic Cerebral Hypoperfusion [0.03%]
非肽类MAS1受体激动剂AVE0991可减轻慢性脑低灌注大鼠海马突触的退变
Xiao Xue,Rui Duan,Qiao-Quan Zhang et al.
Xiao Xue et al.
Background: Chronic cerebral hypoperfusion (CCH) is a contributing factor for neurodegenerative diseases. As a recently identified heptapeptide of the brain renin-angiotensin system, angiotensin-(1-7) has been revealed to...
Clinical Efficacy of Functional Electrical Stimulation-assisted Rehabilitation Cycling on the Function of Lower Limbs in Patients with Stroke [0.03%]
功能性电刺激辅助康复自行车运动对中风患者下肢功能的临床疗效研究
Xiao-Hua Zhang,Jia-Yu Liu,Ping Han et al.
Xiao-Hua Zhang et al.
Objective: To explore the efficacy of functional electrical stimulation (FES)-assisted rehabilitation cycling on the functional recovery of lower limbs in patients with hemiplegic stroke and the assessment value of surfac...
Randomized Controlled Trial
Current neurovascular research. 2021;18(3):318-323. DOI:10.2174/1567202618666211012094424 2021