Combination of Peroxisome Proliferator-activated Receptor Gamma (PPARγ) Agonist and PPAR Gamma Co-Activator 1α (PGC-1α) Activator Ameliorates Cognitive Deficits, Oxidative Stress, and Inflammation in Rodent Model of Parkinson's Disease [0.03%]
胰岛素增敏剂和激活PGC-1α的化合物对帕金森病模型大鼠认知障碍、氧化应激及炎症的影响作用及其机制研究
Nihar Ranjan Das,Bhupesh Vaidya,Pragyanshu Khare et al.
Nihar Ranjan Das et al.
Background: PPAR gamma co-activator 1α (PGC-1α) is known as the master regulator of mitochondrial biogenesis. It is also a co-activator of peroxisome proliferator-activated receptor-gamma (PPARγ) and plays a role in pr...
Malnutrition could Predict 3-month Functional Prognosis in Mild Stroke Patients: Findings from a Nationwide Stroke Registry [0.03%]
营养不良可否预测轻型卒中患者的3个月功能预后？来自全国性卒中登记的数据
Haiqiang Qin,Anxin Wang,Yingting Zuo et al.
Haiqiang Qin et al.
Background: Previous studies showed the inconsistent effects of malnutrition contributing to the poor prognosis of stroke. This study aims to explore the effect of malnutrition on 3- month functional prognosis of stroke p...
Multicenter Study
Current neurovascular research. 2021;18(5):489-496. DOI:10.2174/1567202619666211217130221 2021
A Novel Nomogram for Predicting Prognosis after Mechanical Thrombectomy in Patients with Acute Ischemic Stroke [0.03%]
急性缺血性卒中患者机械取栓术后预后的新型预测列线图模型
Huiling Sun,Feng Zhou,Guoxing Zhang et al.
Huiling Sun et al.
Background: Mounting evidence has shown that mechanical thrombectomy (MT) improves clinical outcomes for large vessel occlusions (LVOs) in patients with acute ischemic stroke (AIS) of the anterior circulation. The present...
Regulatory Mechanism miR-302a-3p/E2F1/SNHG3 Axis in Nerve Repair Post Cerebral Ischemic Stroke [0.03%]
脑卒中后神经修复过程中miR-302a-3p/E2F1/SNHG3轴的调控机制研究
Xiaoyu Sun,Lizhou Wang,Xueqing Huang et al.
Xiaoyu Sun et al.
Objective: Cerebral ischemic stroke (CIS) remains a primary cause of death worldwide. The current knowledge has identified the implication of microRNAs (miRNAs) in the pathophysiology of CIS. This study investigated the m...
Plasma Retinol Binding Protein 4 as a Biomarker for Detecting Progressive Stroke and Prediction of Early Prognosis in Patients with Acute Ischemic Stroke [0.03%]
血浆视黄醇结合蛋白4作为检测急性缺血性卒中患者进行性卒中的生物标志物及早期预后判断的价值研究
Shuqiong Liu,Jiande Li,Xiaoming Rong et al.
Shuqiong Liu et al.
Aim and Purpose: Progressive Stroke (PS) lacks effective treatment measures and leads to serious disability or death. Retinol binding protein 4 (RBP4) could be closely associated with acute ischemic stroke (AIS). We aimed to explore plasma ...
Contralateral Posterior Putaminal 18F-Fluorodopa Uptake in Mild Stage Parkinson's Disease: A PET/CT Study [0.03%]
帕金森病轻微阶段的对侧后部底丘脑18氟多巴摄取研究：一项PET / CT研究
Lei-Lei Zhou,Si-Yu Wang,You-Yong Tian et al.
Lei-Lei Zhou et al.
Objective: Previous studies revealed that 18F-FDOPA uptake was significantly decreased in the subregions of striatum contralateral to the side with predominant symptoms and was helpful for improving the early diagnostic a...
The Prognostic Significance of White Blood Cell and Platelet Count for Inhospital Mortality and Pneumonia in Acute Ischemic Stroke [0.03%]
白细胞和血小板计数对急性缺血性脑卒中住院死亡率和肺炎的预后意义
Shoujiang You,Xin Sun,Yi Zhou et al.
Shoujiang You et al.
Background: We investigated the combined effect of white blood cell (WBC) and platelet count on in-hospital mortality and pneumonia in acute ischemic stroke (AIS) patients. ...
Association of Serum Interleukin-34 and Insulin Resistance with Cognitive Impairment in Patients with Cerebral Small Vessel Disease [0.03%]
血清白细胞介素-34及胰岛素抵抗与脑小血管病患者认知障碍的关系
Tiantian Jiang,Yong Zhou,Dongmei Zhang et al.
Tiantian Jiang et al.
Objective: Insulin resistance (IR) is a key pathological process during the development of cerebral small vessel disease (CSVD) and vascular cognitive impairment (VCI). The triglyceride- glucose index (TyG index) is consi...
A Study on Relationship of Hounsfield Units Value on Non-contrast Computer Tomography and Recanalization of Intravenous Thrombolysis [0.03%]
非对比计算机断层扫描中霍恩斯菲尔德单位值与静脉溶栓再通的关系研究
Zhen Wang,Kangping Song,Wei Xu et al.
Zhen Wang et al.
Objective: The objective of this study is to determine whether the administration of intravenous alteplase would be beneficial or futile to patients with acute ischemic stroke caused by large vessel occlusion (LVO) before...
MiR-582-5p Attenuates Neonatal Hypoxic-ischemic Encephalopathy by Targeting High Mobility Group box 1 (HMGB1) through Inhibiting Neuroinflammation and Oxidative Stress [0.03%]
微小RNA-582-5p通过抑制神经炎症和氧化应激来靶向高迁移率族盒1（HMGB1）从而减轻新生儿缺氧缺血性脑病
Guang Yang,Zhimin Xue,Yuan Zhao
Guang Yang
Background: MiR-582-5p has been demonstrated to protect against ischemic stroke. However, its implication in the progression of neonatal hypoxic-ischemic encephalopathy (HIE) has not been explored. ...