Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury [0.03%]
缬沙坦通过缺血再灌注损伤保护高脂饮食小鼠心肌功能
Simrat Kaur,Kuldeep Kumar,Nirmal Singh et al.
Simrat Kaur et al.
Aim: The study investigates the effect of Valsartan, an Angiotensin II type 1 receptor blocker (ARB), on the blunted neuroprotective response of ischemic post-conditioning (iPoCo) in rats subjected to High Fat Diet (HFD)....
Curcumin Alleviates Oxidative Stress, Neuroinflammation, and Promotes Behavioral Recovery After Traumatic Brain Injury [0.03%]
姜黄素通过减轻氧化应激和神经炎症及促进行为恢复来缓解创伤性脑损伤
Bing Chen,Quan-Xing Shi,Chuang Nie et al.
Bing Chen et al.
Background: Neuroinflammation and oxidative stress after traumatic brain injury (TBI) can further lead to neuronal apoptosis, which plays a crucial role in the process of neuron death. Curcumin, which is derived from the ...
DL-3-n-butylphthalide Attenuates Cerebral Ischemia-Reperfusion Injury by Inhibiting Mitochondrial Omi/HtrA2-Mediated Apoptosis [0.03%]
DL-3-丁基苯酞通过抑制线粒体Omi/HtrA2介导的细胞凋亡减轻脑缺血再灌注损伤
Shuo Huang,Qianyan He,Xin Sun et al.
Shuo Huang et al.
Background: Ischemic stroke is a major cause of death and disability worldwide and results from inadequate cerebrovascular blood supply; mitochondrial dysfunction plays an essential role in its pathogenesis. DL-3-n-butylp...
APOE4: A Culprit for the Vulnerability of COVID-19 in Alzheimer's Patients [0.03%]
APOE4：阿尔茨海默病患者新冠肺炎易感性的罪魁祸首
Ahsas Goyal,Prashant Singh Kushwah,Neetu Agrawal et al.
Ahsas Goyal et al.
Apolipoprotein E4 (APOE4) is one of the primary genetic risk factors for late-onset of Alzheimer's disease (AD). While its primary function is to transport cholesterol, it also regulates metabolism, aggregation, and deposition of amyloid-β...
Paeonol Attenuates the Endothelial-to-Mesenchymal Transition Induced by TGF-β1 in Human Umbilical Vein Endothelial Cells through ALK5- Smad2/3 Signaling Pathway [0.03%]
白樟素通过ALK5-Smad2/3信号通路削弱转化生长因子-β1诱导的人脐静脉内皮细胞向间充质细胞的转分化作用研究
Yulong Yang,Yuning Liang,Xiaoyan Shi et al.
Yulong Yang et al.
Background: Paeonol (Pae), the main active compound of the root of Paeonia albiflora, is efficacious in treating atherosclerosis (AS). Endothelial dysfunction is throughout the pathological progression of AS. It is expect...
Effects of Different Etiologies of Anterior Circulation Tandem Lesions on Short-term Prognosis of Acute Ischemic Stroke [0.03%]
不同病因的前循环串联病变急性缺血性脑卒中的短期预后研究
Zhichao Huang,Yingying Xu,Shoujiang You et al.
Zhichao Huang et al.
Introduction: The prognosis of anterior circulation tandem lesions caused by carotid artery dissection (CAD) and large artery atherosclerosis (LAA) after mechanical thrombectomy is controversial. By analyzing the clinical...
Cerium Oxide Nanoparticles Ameliorate Oxidative Stress, Inflammation, and Pain Behavior in Neuropathic Rats [0.03%]
纳米氧化铈颗粒通过改善大鼠神经病理性疼痛的氧化应激、炎症和痛行为而产生镇痛作用
Fatemeh Forouzanfar,Ali Mohammad Pourbagher-Shahri,Majid Darroudi et al.
Fatemeh Forouzanfar et al.
Background: Neuropathic pain originating from a dysfunction in the nervous system is often intractable and chronic. Recently, several studies using nanoparticles suggested a new way to control neuropathic pain. This study...
CT Perfusion Alterations in Patients with Symptomatic and Asymptomatic Unilateral Middle Cerebral Artery Severe Stenosis or Occlusion [0.03%]
症状性与无症状性单侧大脑中动脉严重狭窄或闭塞患者的CT灌注成像改变
Mengke Ban,Zhigang Zhang,Junyan Yue et al.
Mengke Ban et al.
Objective: To investigate the changes in CT perfusion between symptomatic and asymptomatic patients with unilateral middle cerebral artery severe stenosis or occlusion. ...