Pharmacological Evaluation of the Combination Therapy of Novel Herbal Mixture in Polycystic Ovary Syndrome [0.03%]
新型草药混合物治疗多囊卵巢综合征的药理评价
Chandana Pyne,Chandra Shekhar Barik,Rakesh Verma et al.
Chandana Pyne et al.
Introduction: An endocrine condition known as Poly-Cystic Ovarian Syndrome (PCOS) makes females of reproductive age more susceptible to insulin resistance, excessive levels of male hormones, and delayed ovulation. It is t...
Rupali Chauhan,Sushma Devi,Thakur Gurjeet Singh
Rupali Chauhan
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide, and need novel molecular targets for improved diagnosis and treatment. There are some potential new molecular targets for CVD treatment, including mi...
Engineering Strategies for Hyaluronan Synthesis: A Review of Enzyme Modifications, Strain Selection, and Molecular Weight Control [0.03%]
透明质酸合成工程策略研究：酶改造、菌株选育及分子量调控综述
Mortaza Eivazi,Tahereh Ebrahimi,Kamran Hosseini et al.
Mortaza Eivazi et al.
Hyaluronan is a biopolymer with significant biological and commercial importance, particularly due to its applications in medical, cosmetic, and tissue engineering fields. The molecular weight of HA is a key factor that influences its biolo...
Mai Suan Li,Adam Liwo,Yuko Okamoto
Mai Suan Li
Insects on the Plate: Nutritional Benefits, Health Impacts, and Market Dynamics [0.03%]
盘中昆虫：营养益处、健康影响及市场动态
Ravi Kumar Mittal,Gaurav Krishna,Sohini Chowdhury et al.
Ravi Kumar Mittal et al.
Introduction: Edible insects are gaining popularity as a sustainable source of proteins, minerals, vitamins, and bioactive compounds. Insects are nutritious, antibacterial, anti-inflammatory, and antioxidant. Modern proce...
Comprehensive Review of L-Lysine: Chemistry, Occurrence, and Physiological Roles [0.03%]
L-赖氨酸综合评述：化学性质、分布和生理功能
Mohd Hashim,Intekhab Alam,Mohammad Ahmad et al.
Mohd Hashim et al.
L-lysine, an essential amino acid, is indispensable for numerous biological functions, including protein synthesis, collagen crosslinking, mineral absorption, and carnitine biosynthesis. Its biosynthesis occurs via the Diaminopimelate (DAP)...
Plant SUT Sucrose Transporters: Structure, Evolution and Biological Functions [0.03%]
植物SUT蔗糖转运蛋白：结构、进化及生物学功能
Zaibao Zhang,Tianyu Fan,Luhui Wu et al.
Zaibao Zhang et al.
Sucrose transporters (SUTs) are essential for exporting and moving sucrose from source leaves to sink organs in plants. Many researchers have addressed SUT functions in plant development regulation and stress responses, as well as on the tr...
Jia Chen,Yumin Huang,Yafei Wang et al.
Jia Chen et al.
Background: Sialic acid-binding immunoglobulin-like lectins (Siglecs) are cell-surface immunological receptors predominantly expressed on immune cells such as monocytes, macrophages, and dendritic cells. They play a cruci...
Molecular Degraders: A Comprehensive Review of Small Molecule Induced Protein Degradation Strategies [0.03%]
分子降解剂：小分子诱导蛋白质降解策略综述
Deepanshu Sindhwani,Kaushal Arora,Pankaj Kumar et al.
Deepanshu Sindhwani et al.
Molecular degraders represent a ground-breaking class of small molecules revolutionizing drug discovery through the selective elimination of disease-causing proteins, including those previously deemed "undruggable." This review provides a c...
Prediction of Antithrombin Activity and Bioavailability of a Synthetic Peptide Using a Decision Tree Algorithm [0.03%]
基于决策树算法预测合成肽的抗凝血酶活性及生物利用度
Sergei L Tikhonov,Olga O Babich,Stanislav A Sukhikh et al.
Sergei L Tikhonov et al.
Background: Thrombosis is a major cause of mortality from cardiovascular disease (CVD). The use of known antithrombin drugs is limited by the presence of side effects and complications. Peptides may be promising antithrom...