Uncovering Herbivory Defense Responsive Proteins in Chickpea (Cicer spp.) Through Mass Spectrometry-Based Proteomics [0.03%]
基于质谱的蛋白质组学在 chickpea (Cicer spp.) 中鉴定食草动物防御响应蛋白
Alakesh Das,Arunima S,Prakash Jyoti Kalita et al.
Alakesh Das et al.
Introduction: The legume pod borer, Helicoverpa armigera, is a major biotic constraint to chickpea production, causing substantial global yield losses. The downstream signaling pathways underlying host-insect interactions...
Activity of Luetzelburgia auriculata Lectin Against Leishmania major Promastigote Via Carbohydrate Recognition Domain [0.03%]
Luetzelburgia auriculata lectin对利什曼原虫的作用机制研究
Yasmim de A Grangeiro,Ana L E Santos,Flávia E V Barbosa et al.
Yasmim de A Grangeiro et al.
Introduction: Leishmaniasis, an infectious disease, significantly impacts patients' quality of life. Current treatments primarily involve glucantime and amphotericin B. Although these drugs are effective, their limitation...
The Relationship between S100A9 Protein Levels and Diabetic Retinopathy among Type 2 Diabetes Patients: A Meta-Analysis [0.03%]
糖尿病视网膜病变患者S100A9蛋白水平的差异表达及临床意义meta分析
Ji Jin,Fangfang Ji,Ji Zhang
Ji Jin
Introduction: The global prevalence of type 2 diabetes is increasing, significantly affecting individuals' quality of life. While traditional symptomatic treatments have demonstrated some therapeutic benefits, their effic...
Aminated Polyrotaxanes as Next-Generation Excipients: Dual Roles in Stabilization and Drug Delivery of Injectable Biologics [0.03%]
可注射生物药物的新型赋形剂聚轮烷：在稳定性和药物递送中的双重作用
Shikha Baghel Chauhan,Indu Singh,Sanjoli Srivastava et al.
Shikha Baghel Chauhan et al.
Introduction: The instability of injectable biologics, such as monoclonal antibodies, cytokines, and enzymes, has become a major challenge in modern pharmaceutical formulation. Traditional formulation additives like PEGs,...
Targeting Drug-Resistant Tuberculosis with Antimicrobial Peptides: Opportunities and Challenges [0.03%]
抗菌肽在耐药结核病治疗中的机遇与挑战
Asad Ahmad,Rufaida Wasim,Anas Islam et al.
Asad Ahmad et al.
Introduction: One of the main causes of infectious disease-related deaths globally is Mycobacterium tuberculosis (M.tb), the causative agent of tuberculosis (TB). Novel treatment strategies are now much more urgent due to...
To Fold, Unfold, or Aggregate: The Induced Coaggregation Mechanism of Amyloidogenic Antimicrobial Peptides for Combating Bacterial Communities [0.03%]
聚集、解聚或聚合：抗菌肽诱导聚集作用的新机制——对抗细菌群体
Oxana V Galzitskaya,Sergey V Kravchenko,Sergei Y Grishin et al.
Oxana V Galzitskaya et al.
Introduction: The rise of antibiotic-resistant bacteria worldwide has spurred the need for new treatment approaches. Antimicrobial Peptides (AMPs) are promising alternatives because of their broad-spectrum effects and nov...
Post-translational Modification that Shines in the Age of Viruses: ISGylation from a Structural Perspective [0.03%]
在病毒时代大放异彩的蛋白质修饰：ISGylation的结构研究视角
Oktay Gocenler,Nilufer Cakir,Cansu Deniz Tozkoparan Ceylan et al.
Oktay Gocenler et al.
Post-translational modifications (PTMs) orchestrate the dynamic functional landscape of proteins, governing cellular immunity, signaling, and stress responses. Among these modifications, ISGylation, a ubiquitin-like conjugation process driv...
PI3K/AKT Signaling as a Molecular Link Between Obesity and Female Infertility [0.03%]
磷脂酰肌醇-3-激酶/蛋白激酶作为肥胖和女性不孕之间联系的分子纽带
Gunvanti Rathod,Pragnesh Parmar
Gunvanti Rathod
Obesity-related female infertility is a result of the intricate interplay between metabolic disorders and reproductive abnormalities. The Phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) signaling pathway is an important molecular medi...
Kalyani R Thombre,Nikita D Rahangdale,Krishna Radheshyam Gupta et al.
Kalyani R Thombre et al.
Introduction: Gut-brain communication depends on neuropeptides and hormones, and the Neuropeptide Y (NPY) family, which includes NPY, Peptide YY (PYY), and Pancreatic Polypeptide (PP), plays an important role. These pepti...
The Production, Properties, and Potential Food Applications of Proteins and Peptides from Marine Sources and their Structure-Function Relationship [0.03%]
海洋源蛋白质及肽的制备、性质及其在食品中应用的结构功能关系研究进展
Esmaeel Mirzakhani,Chi Ching Lee,Tolulope Joshua Ashaolu et al.
Esmaeel Mirzakhani et al.
The oceans, covering over 70% of the Earth's surface, represent a vast and underexplored source of proteins and bioactive peptides with unique structures and functionalities. This review comprehensively examines the production, properties, ...