Reversible and Irreversible Aggregation of Proteins from the FET Family: Influence of Repeats in Protein Chain on Its Aggregation Capacity [0.03%]
含重复序列的FET家族蛋白可逆和不可逆聚集能力的影响研究
Oxana V Galzitskaya
Oxana V Galzitskaya
The discovery of protein chain regions responsible for protein aggregation is an important result of studying of the molecular mechanisms of prion diseases and different proteinopathies associated with the formation of pathological aggregat...
Structural and functional characterization of the proteins responsible for N6-methyladenosine modification and recognition [0.03%]
N6-甲基腺苷修饰及识别的调控机制研究进展
Ke Liu,Yumin Ding,Weiyuan Ye et al.
Ke Liu et al.
More than 100 types of RNA modifications have been identified so far, which are involved in a variety of cellular processes. N6-methyladenosine (m6A), as one most abundant RNA modification, is found in several RNA species, and mainly locate...
Lola M Rafieva,Eugene V Gasanov
Lola M Rafieva
Neurotrophins constitute a family of growth factors that play a key role in the regulation of the development and function of the central and peripheral nervous systems. A common feature of all the neurotrophins is their synthesis in cells ...
Reshaping the protein folding pathway by osmolyte via its effects on the folding intermediates [0.03%]
渗透压调节物通过其对中间态的影响来重塑蛋白质折叠路径
Gurumayum Suraj Sharma,Tanveer Ali Dar,Laishram Rajendrakumar Singh
Gurumayum Suraj Sharma
It is now well established that the protein folding reaction proceeds via accumulation of various intermediate states. Osmolytes, besides their role in protein stabilization, have also been shown to possess the ability of inducing tremendou...
Harsh Mathur,Mary C Rea,Paul D Cotter et al.
Harsh Mathur et al.
The sactibiotics are a recently designated subclass of bacteriocins that contain characteristic cysteine sulphur to α -carbon linkages mediated through post-translational modifications. They are a relatively small subclass of bacteriocins ...
Disintegrins from snake venoms and their applications in cancer research and therapy [0.03%]
蛇毒中的分离 integrins 及其在癌症研究和治疗中的应用
Jéssica Kele Arruda Macêdo,Jay W Fox,Mariana de Souza Castro
Jéssica Kele Arruda Macêdo
Integrins regulate diverse functions in cancer pathology and in tumor cell development and contribute to important processes such as cell shape, survival, proliferation, transcription, angiogenesis, migration, and invasion. A number of snak...
Editorial: hormonal crosstalk in plants: the ultimate determiner of plant fate [0.03%]
编辑观点：植物中的激素交流：决定植物命运的最终因素
Golam Jalal Ahammed
Golam Jalal Ahammed
Isolation and Characterization of L-Tryptophan Ammonia Lyase from Rubrivivax benzoatilyticus Strain JA2 [0.03%]
苯甲酸降解红球菌JA2株L-色氨酸氨裂合酶的分离与鉴定
Ranjith N Kumavath,Ch V Ramana,Ch Sasikala et al.
Ranjith N Kumavath et al.
Ammonia lyase belongs to the family of enzymes that catalyzes the deamination of amino acids. Depending on the relative activity towards the substrates, L-tryptophan ammonia lyase converts L-tryptophan to indole 3-acrylic acid and ammonia. ...
In Silico Protein-Protein Interactions: Avoiding Data and Method Biases Over Sensitivity and Specificity [0.03%]
模拟中的蛋白质-蛋白质相互作用：在敏感性和特异性上避免数据和方法的偏差
Edson Luiz Folador,Alberto Fernandes de Oliveira Junior,Sandeep Tiwari et al.
Edson Luiz Folador et al.
The study of protein-protein interactions (PPIs) can help researchers raise new hypotheses about an organism or disease and guide new experiments. Various methods for the identification and analysis of PPIs have been discussed in the litera...
Computational Biology Tools for Identifying Specific Ligand Binding Residues for Novel Agrochemical and Drug Design [0.03%]
用于新型农用化学品和药物设计的识别特定配体结合残基的计算生物学工具
Izabella Agostinho Pena Neshich,Leticia Nishimura,Fabio Rogerio de Moraes et al.
Izabella Agostinho Pena Neshich et al.
The term "agrochemicals" is used in its generic form to represent a spectrum of pesticides, such as insecticides, fungicides or bactericides. They contain active components designed for optimized pest management and control, therefore allow...