A2 Milk: The Impact of Genetic Variation in Milk Protein on Human Health [0.03%]
A2型牛奶：乳蛋白基因变异对人体健康的影响
Leila Ben Farhat,Hiba Selmi,Violetta Toth et al.
Leila Ben Farhat et al.
Recently, a new type of cow's milk has been commercialized in the markets, called A2 milk. It is derived from a specific allelic composition on chromosome 6. The only difference between A1 and A2 milk results from the polymorphism at the 67...
Jyotsana Dwivedi,Pranay Wal,Subbulakshmi Ganesan et al.
Jyotsana Dwivedi et al.
With its high potential, mRNA nanomedicine has become one of the transformative frontiers of modern therapeutic strategies for treating and preventing a wide array of diseases. This review article covers recent developments in mRNA nanomedi...
In-Situ Synthesis of Silver Nanoparticle within Self-Assembling Ultrashort Peptide Hydrogel as Antibacterial with Wound Healing Properties [0.03%]
自组装超短肽水凝胶中银纳米粒子原位合成制备兼具抗菌和促进伤口愈合性能的材料
Firuza Begum,Aman Kumar Mahto,Shalini Kumari et al.
Firuza Begum et al.
Introduction/objectives: Silver nanoparticles [AgNPs] are promising antimicrobial agents, but their synthesis often involves toxic reducing agents. To address this, we developed a green synthesis methodology employing an ...
Exploring Placental Protein-Target Protein Interactions: In Silico and In Vitro Approaches for Osteoarthritis Therapy [0.03%]
基于胎盘蛋白靶点的抗骨关节炎药物筛选及机制研究
Jithu Jerin James,K V Sandhya,Parasuraman Pavadai et al.
Jithu Jerin James et al.
Background: Osteoarthritis (OA) is a persistent joint condition marked by gradual softening and breakdown of articular cartilage. Current research in OA treatment explores biologics that target proinflammatory cytokines a...
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis [0.03%]
揭秘微小核糖核酸分子机制：精神分裂症发病相关蛋白质间相互作用
Sumel Ashique,Radheshyam Pal,Anas Islam et al.
Sumel Ashique et al.
Schizophrenia is now diagnosed mostly based on symptoms and physical signs rather than the patient's pathological and physiological markers. While oncologists once felt satisfied when their patients experienced a long remission, today, they...
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma [0.03%]
DPYS的作用机制及其作为软组织肉瘤预后生物标志物的价值探讨
Guizhen Lyu,Dongbing Li
Guizhen Lyu
Background: Dihydropyrimidinase (DPYS), a pivotal enzyme in the pyrimidine synthesis pathway, has been increasingly studied for its potential role in cancer therapy. While its presence has been noted in various cancers, i...
Network Pharmacology and Experiments to Verify the Effect and Potential Mechanism of Baicalein on Osteoporosis [0.03%]
网络药理学与实验验证黄酮对骨质疏松症的效果及潜在机制研究
Huang Xudong,Li Qi,Ma Wenlong et al.
Huang Xudong et al.
Background: Baicalein (BN), a potent flavonoid derived from scutellaria scutellaria, exhibits an array of noteworthy attributes, such as anti-inflammatory, antibacterial, and antipyretic properties. Furthermore, its poten...
Effectiveness and Current Status of Icariin in the Treatment of Rotator Cuff Injury Associated with Osteoporosis [0.03%]
淫羊藿素在治疗与骨质疏松相关的 rotator cuff 损伤中的有效性和现状
Xian-Quan Zhang,Guang-Hui Zhou,Zhuo-Xu Gu et al.
Xian-Quan Zhang et al.
Rotator cuff injury is a disease in which the muscle and tendon that constitute the rotator cuff are torn causing shoulder pain and limited function. Osteoporosis (OP) is a systemic metabolic bone disease characterized by decreased bone mas...
Guangzhou Sun,Quanshan Shi,Yuting Song et al.
Guangzhou Sun et al.
Mitochondria are organelles in eukaryotic organisms with an electron transport chain consisting of four complexes (i.e., CI, CII, CIII, and CIV) on the inner membrane, which have functions such as providing energy, electron transport, and g...
Amyloid-β Clearance with Monoclonal Antibodies: Transforming Alzheimer's Treatment [0.03%]
使用单克隆抗体清除淀粉样蛋白-β：改变阿尔茨海默病的治疗方式
Rabab Fatima,Yumna Khan,Mudasir Maqbool et al.
Rabab Fatima et al.
Alzheimer's disease (AD) is a progressive condition that causes the degeneration of nerve cells, leading to a decline in cognitive abilities and memory impairment, significantly affecting millions around the globe. The primary pathological ...