Phytochemistry and pharmacology of Allii Macrostemonis Bulbus, a traditional Chinese medicine [0.03%]
传统中药苍术（Allii Macrostemonis Bulbus）的植物化学和药理学研究进展
Zhi-Hong Yao,Zi-Fei Qin,Yi Dai et al.
Zhi-Hong Yao et al.
Allii Macrostemonis Bulbus (Xiebai in Chinese), as a famous traditional Chinese medicine, has great medicinal and dietary values since ancient times. In China, the dry bulbs of Allium macrostemon and Allium chinense are both used as its ori...
Integrating qualitative and quantitative characterization of Prunellae Spica by HPLC-QTOF/MS and HPLC-ELSD [0.03%]
高效液相色谱法结合质谱和 evaporative light scattering detection 检测器用于穿心莲的质量评价
Jie Yang,Yuan-Jia Hu,Bo-Yang Yu et al.
Jie Yang et al.
The present study was designed to analyze the major constituents in Prunellae Spica and establish a method for simultaneous determination of two constituents contained in Prunellae Spica. High performance liquid chromatography coupled with ...
Synthesis and evaluation of benzylisoquinoline derivatives for their inhibition on pancreatic lipase and preadipocyte proliferation [0.03%]
苯基异喹啉衍生物的合成及其对胰腺脂肪酶和前脂肪细胞增殖抑制作用的研究
Feng Tian,Hao-Yu Lv,Ji-Long Zou et al.
Feng Tian et al.
The present study was designed to synthesize and evaluate a series of benzylisoquinoline derivatives. These compounds were synthesized by Bischler-Napieralski cyclization to yield 1-benzyl-3,4-dihydroisoquinolines, and the products were obt...
Xu Zhang,Zhi-Xiang Zhu,Juan Wang et al.
Xu Zhang et al.
Two new oleanane-type triterpenoids, parvifolactone A (1) and rubuside P (2), together with 11 known triterpenoids, fupenzic acid (3), 18,19-seco,2α,3α-dihydroxyl-19-oxo-urs-11,13(18)-dien-28-oic acid (4), euscaphic acid (5), maslinic aci...
A polysaccharide purified from Radix Adenophorae promotes cell activation and pro-inflammatory cytokine production in murine RAW264.7 macrophages [0.03%]
一株明党参多糖的提取物通过促进小鼠RAW264.7巨噬细胞活化及促炎症因子生成发挥免疫调节作用
Jing-Wen Li,Yang Liu,Bao-Hui Li et al.
Jing-Wen Li et al.
Radix Adenophorae, a traditional Chinese medicine, has been reported to have a variety of biological functions. In the present study, a polysaccharide component, Radix Adenophorae Polysaccharide (RAPS), was purified from Radix Adenophorae b...
Antagonistic effects of extracts from Artemisia rupetris L. and Leontopodium leontopodioides to CC chemokine receptor 2b (CCR2b) [0.03%]
Artemisia rupetris L.和Leontopodium leontopodioides的提取物对CC趋化因子受体2b(CCR2b)拮抗作用的影响
Qin-Wei Yu,Jie Hu,Hao Wang et al.
Qin-Wei Yu et al.
The present study was designed to establish a suitable assay to explore CCR2b receptor antagonists from the natural products of Artemisia rupetris and Leontopodium leontopodioides. An aequorin assay was developed as a cell-based assay suita...
Brazilein inhibits neuronal inflammation induced by cerebral ischemia and oxygen-glucose deprivation through targeting NOD2 expression [0.03%]
巴西藤通过靶向NOD2表达抑制脑缺血和氧葡萄糖剥夺诱导的神经炎症
Xiao-Jin Yan,Yu-Shuang Chai,Zhi-Yi Yuan et al.
Xiao-Jin Yan et al.
Brazilein is reported to have immunosuppressive effect on cardiovascular and cerebral-vascular diseases. The essential roles of innate immunity in cerebral ischemia are increasingly identified, but no studies concerning the influence of bra...
Anti-neuro-inflammatory effects of Nardostachys chinensis in lipopolysaccharide-and lipoteichoic acid-stimulated microglial cells [0.03%]
Nardostachys chinensis的抗神经炎症作用及其对脂多糖和脂磷壁酸刺激的小胶质细胞的影响
Sun Young Park,Young Hun Kim,Geuntae Park
Sun Young Park
Excessive microglial cell activation is related to the progression of chronic neuro-inflammatory disorders. Heme oxygenase-1 (HO-1) expression mediated by the NFE2-related factor (Nrf-2) pathway is a key regulator of neuro-inflammation. Nar...
Hoon Jeon,Dong Seok Cha
Hoon Jeon
The present study investigated the effects and underlying mechanism of ethylacetate fraction of Ribes fasciculatum (ERF) on the lifespan and stress tolerance using a Caenorhabditis elegans model. The longevity activity of ERF was determined...
Recent advances in phytochemistry and pharmacology of C21 steroid constituents from Cynanchum plants [0.03%]
近年来防己科植物C２１甾体化学与药理学研究进展
Xiao-Jie Gu,Da-Cheng Hao
Xiao-Jie Gu
Cynanchum is one of the most important genera in Asclepiadaceae family, which has long been known for its therapeutic effects. In this genus, 16 species are of high medicinal value. The extracts of the root and/or rhizome parts have been ap...