Isolation and identification of two new compounds from marine-derived fungus Acremonium fusidioides RZ01 [0.03%]
从海洋来源半帚霉菌中分离鉴定两种新化合物
Xiao An,Bao-Min Feng,Gang Chen et al.
Xiao An et al.
Two new compounds, (22E)-25-carboxy-8β,14β-epoxy-4α,5α-dihydroxyergosta-2,22-dien-7-one (1) and fusidione (3), along with two known compounds, 5α,8α-epidioxy ergosta-6,22-diene-3β-ol (2) and microperfuranone (4), were isolated from t...
17-[16,17-Dihydroxycyclooctatinyl]-hexaketide ester from Streptomyces sp. SR107 [0.03%]
来自SR107链霉菌的17-（16，17-二羟基环辛烯基）己酸内酯类化合物
Meng-Yu-Jie Liu,Shan-Ren Li,L U Chun-Hua
Meng-Yu-Jie Liu
A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester (1), a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was ...
Marsdeniae tenacissimae extract (MTE) suppresses cell proliferation by attenuating VEGF/VEGFR2 interactions and promotes apoptosis through regulating PKC pathway in human umbilical vein endothelial cells [0.03%]
崖木提取物通过下调血管内皮生长因子/血管内皮生长因子受体-2的相互作用抑制细胞增殖并调节蛋白激酶C途径促进人脐静脉内皮细胞凋亡
Bing-Yu Chen,Dong Chen,Jian-Xin Lyu et al.
Bing-Yu Chen et al.
Marsdeniae tenacissimae extract (MTE), commonly known as Xiao-Ai-Ping in China, is a traditional Chinese herb medicine capable of inhibiting proliferation and metastasis and boosting apoptosis in various cancer cells. However, little is kno...
In vitro cytotoxicity and antimicrobial activity of Talaromyces flavus SP5 inhabited in the marine sediment of Southern Coast of India [0.03%]
印度南部沿海海洋沉积物中寄居的Talaromyces flavus SP5的体外细胞毒性和抗菌活性
Bibin G Anand,C K Navin Thomas,S Prakash
Bibin G Anand
Marine sediment samples were collected from the coastal areas of Southern India, particularly in Kanyakumari District. Twenty-eight different fungal strains were isolated. The screening of fungi from marine sediment was done to isolate a po...
Thymoquinone inhibits the migration of mouse neuroblastoma (Neuro-2a) cells by down-regulating MMP-2 and MMP-9 [0.03%]
补骨脂内酯抑制鼠神经母细胞瘤( Neuro-2a )细胞迁移通过下调基质金属蛋白酶-2和基质金属蛋白酶-9表达
Paramasivam Arumugam,Raghunandhakumar Subramanian,Jayaseelan Vijayashree Priyadharsini et al.
Paramasivam Arumugam et al.
Thymoquinone (TQ), an active component derived from the medial plant Nigella sativa, has been used for medical purposes for more than 2 000 years. Recent studies have reported that TQ blocked angiogenesis in animal model and reduced migrati...
ITS2 barcoding DNA region combined with high resolution melting (HRM) analysis of Hyoscyami Semen, the mature seed of Hyoscyamus niger [0.03%]
含有阿托品的成熟黑善种子高效分辨熔解曲线分析及其ITS2条形码区域鉴定研究
Chao Xiong,Zhi-Gang Hu,Yuan Tu et al.
Chao Xiong et al.
Hyoscyami Semen, the mature dried seed of Hyoscyamus niger L., has long been used as a traditional Chinese medicine to treat human diseases. Hyoscyami Semen is found in local markets in China. In markets, sellers and buyers commonly inadver...
Classification of natural products as sources of drugs according to the biopharmaceutics drug disposition classification system (BDDCS) [0.03%]
基于生物药剂学药物处置分类系统的天然产物药物来源分类法
Ji Li,Caroline A Larregieu,Leslie Z Benet
Ji Li
Natural products (NPs) are compounds that are derived from natural sources such as plants, animals, and micro-organisms. Therapeutics has benefited from numerous drug classes derived from natural product sources. The Biopharmaceutics Drug D...
MicroRNAs mediate therapeutic and preventive effects of natural agents in breast cancer [0.03%]
微小核糖核酸在天然抗乳腺癌制剂的预防和治疗作用中的介质功能
Zhipin Liang,Yaguang Xi
Zhipin Liang
MicroRNAs (miRNAs) are a set of non-coding small RNA molecules that play a critical role in regulation of protein coding genes in cells. MiRNAs have been extensively studied as novel biomarkers, therapeutic targets, and new drugs in various...
Eurycoma Longifolia as a potential adoptogen of male sexual health: a systematic review on clinical studies [0.03%]
厄赖科马长叶作为潜在的雄性生殖系统适应原：临床研究系统综述
Hnin Ei Thu,Isa Naina Mohamed,Zahid Hussain et al.
Hnin Ei Thu et al.
Eurycoma longifolia (EL) has been well recognized as a booster of male sexual health. Over the past few decades, numerous in vivo animal studies and human clinical trials have been conducted across the globe to explore the promising role of...
Effects of boiling duration in processing of White Paeony Root on its overall quality evaluated by ultra-high performance liquid chromatography quadrupole/time-of-flight mass spectrometry based metabolomics analysis and high performance liquid chromatography quantification [0.03%]
基于UHPLC-Q-TOFMS代谢组学分析及HPLC定量的白芍炮制过程中煮制时间对其整体质量影响评价
Kong Ming,Jun Xu,Huan-Huan Liu et al.
Kong Ming et al.
Boiling processing is commonly used in post-harvest handling of White Paeony Root (WPR), in order to whiten the herbal materials and preserve the bright color, since such WPR is empirically considered to possess a higher quality. The presen...