Antioxidant and cardioprotective effects of Ilex cornuta on myocardial ischemia injury [0.03%]
冬青属Cornuta对抗氧化和心血管保护的效应及其对心肌缺血损伤的影响
Yan Yuan,Shu Pan,Shi-Lin Yang et al.
Yan Yuan et al.
Previous studies have indicated that the Ilex genus exhibits antioxidant, neuroprotective, hepatoprotective, and anti-inflammatory activities. However, the pharmacologic action and mechanisms of Ilex cornuta against cardiac diseases have no...
Pharmacology of mangostins and their derivatives: A comprehensive review [0.03%]
Mango酸及衍生物的药理学：综述性评论
Ming-Hui Wang,Kuo-Jun Zhang,Qin-Lan Gu et al.
Ming-Hui Wang et al.
Mangosteen (Garcinia mangostana Linn.) is a well-known tropical tree indigenous to Southeast Asia. Its fruit's pericarp abounds with a class of isoprenylated xanthones which are referred as mangostins. Numerous in vitro and in vivo studies ...
Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis [0.03%]
条芩中五种活性成分的分布规律研究
Rong-Xiu Liu,Guo-Hu Song,Pei-Gen Wu et al.
Rong-Xiu Liu et al.
As an important herbaceous plant, Scutellaria baicalensis Georgi (Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided into two primary types,...
Pharmacokinetics and correlation between in vitro release and in vivo absorption of bio-adhesive pellets of panax notoginseng saponins [0.03%]
三七总皂苷生物黏附药丸的体内血浆浓度与体外释放的相关性及药动学研究
Ying Li,Yun Zhang,Chun-Yan Zhu
Ying Li
The present study was designed to prepare and compare bio-adhesive pellets of panax notoginseng saponins (PNS) with hydroxy propyl methyl cellulose (HPMC), chitosan, and chitosan : carbomer, explore the influence of different bio-adhesive m...
Influence of ultrafiltration membrane on ophiopogonins and homoisoflavonoids in Ophiopogon japonicus as measured by ultra-fast liquid chromatography coupled with ion trap time-of-flight mass spectrometry [0.03%]
基于超滤膜的乌药内酯和异黄酮类成分的影响研究及其UFLC-ITD-TOFMS指纹图谱分析方法学建立
Chun-Hua Liu,Jin Qi,Da-Zheng Zhou et al.
Chun-Hua Liu et al.
Ultrafiltration is one of the most fascinating technologies, which makes it possible to improve the quality of traditional medicines for application in the pharmaceutical industry. However, researchers have paid little attention to the effe...
Three new triterpenoids isolated from the aerial parts of Ilex cornuta and protective effects against H2O2-induced myocardial cell injury [0.03%]
三种冬青属大叶冬青化学成分的分离鉴定及抗氧化和心肌保护作用研究
Shan-Shan Li,Yan-Li Liu,Qiong-Ming Xu et al.
Shan-Shan Li et al.
In the present study, three new triterpenoids, 23-hydroxyurs-12, 18-dien-28-oic acid 3β-O-α-L-arabinopyranoside (1), 23-hydroxyurs-12, 18-dien-28-oic acid 3β-O-β-D-glucuronopyranoside-6-O-methyl ester (2), and urs-12, 18-dien-28-oic aci...
Soft coral Cespitularia stolonifera: New cytotoxic ceramides and gastroprotective activity [0.03%]
树苔软珊瑚Cespitularia stolonifera的抗肿瘤二萜茋类新骨架分子及胃保护活性研究
Abdelsamed I Elshamy,Walaa A El-Kashak,Heba M I Abdallah et al.
Abdelsamed I Elshamy et al.
In the present study, a new ceramide, namely 2S, 3R-4E, 8E-2-(heptadecanoylamino)-heptadeca-4, 8-diene-1, 3-diol (1), along with four known steroids, including 24-methylcholesta-5, 24(28)-diene-3β-ol (2), 24-methylcholesta-5, 24(28)-diene-...
Development of specific and quantitative methods for the quality control of the polysaccharides from sea-tangle and sargassum [0.03%]
海带和鼠李糖乳杆菌多糖质量控制的定性及定量方法研究
Hua-Li Long,Jing-Xian Zhang,Ji-Ling Guo et al.
Hua-Li Long et al.
Polysaccharides from numerous traditional Chinese medicines have been proven as the bioactive ingredients and are hence used as the quality control markers. However, the assessment criteria always show a poor specificity, due to the lack of...
Synthesis and biological evaluation of nitric oxide (NO)-hydrogen sulfide (H2S) releasing derivatives of (S)-3-n-butylphthalide as potential antiplatelet agents [0.03%]
(S)-3-正丁基苯并呋喃-1,3-二酮释放一氧化氮(NO)-氢硫化物(H₂S)衍生物的合成及其作为潜在抗血小板药物的生物学评价研究
Xiao-Li Wang,Zhao-Ya Wang,Jing-Jing Ling et al.
Xiao-Li Wang et al.
In the present study, a series of novel nitric oxide-hydrogen sulfide releasing derivatives of (S)-3-n-butylphthalide ((S)-NBP) were designed, synthesized, and evaluated as potential antiplatelet agents. Compound NOSH-NBP-5 displayed the st...
Regio- and stereo-selective hydroxylations of ingenane diterpenoids by Mortierella ramanniana and Gibberella fujikuroi [0.03%]
里氏节毛霉和稻瘟灵菌对脑素二萜的区域选择性和立体选择性羟基化反应
Yi-Qing Wu,Yue Cao,Xin Liu et al.
Yi-Qing Wu et al.
The regio- and stereo-selective hydroxylations of two ingenane diterpenoids, 20-deoxyingenol (1) and 13-oxyingenol dodecanoat (2), by the filamentous fungi Mortierella ramanniana and Gibberella fujikuroi were investigated in the present stu...