Two new phragmalin-type limonoids orthoesters from Entandrophragma candollei [0.03%]
埃氏沙比利木中两种新的香豆 Lindenane 型柠檬素ortho酯类化合物
Olga Quasie,Hui Li,Jun Luo et al.
Olga Quasie et al.
Two new phragmalin-type limonoids orthoesters, encandollens A and B (1 and 2), were isolated from the stem barks of Entandrophragma candollei collected in Ghana. The structures of these compounds were elucidated on the basis of HR-ESI-MS, 1...
Protosappanin A exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia [0.03%]
Protosappanin A通过抑制JAK2-STAT3信号通路发挥抗神经炎症作用：BV2小胶质细胞内LPS诱导模型中的研究
Li-Chao Wang,Li-Xi Liao,Ming-Bo Zhao et al.
Li-Chao Wang et al.
Microglial activation and resultant neuroinflammatory response are implicated in various brain diseases including Alzheimer's disease and Parkinson's disease. Treatment with anti-neuroinflammatory agents could provide therapeutic benefits f...
Mangiferin ameliorates insulin resistance by inhibiting inflammation and regulatiing adipokine expression in adipocytes under hypoxic condition [0.03%]
mango叶黄素通过抑制炎症和调节缺氧条件下脂肪细胞的脂联素表达来改善胰岛素抵抗
Chao-Qiang Yang,Jing-Hua Xu,Dan-Dan Yan et al.
Chao-Qiang Yang et al.
Adipose tissue hypoxia has been recognized as the initiation of insulin resistance syndromes. The aim of the present study was to investigate the effects of mangiferin on the insulin signaling pathway and explore whether mangiferin could am...
Advance in quality assessment of Chinese materia medica using microscopic and morphological methods [0.03%]
显微和形态学方法在中药材质量评价中的应用进展
Xiao-Su Miao,Qing-Yu Cui,Zhao-Yi Wang et al.
Xiao-Su Miao et al.
Quality evaluation plays a vital role in ensuring safety and effectiveness of Chinese materia medica (CMM). Microscopic and morphological technologies can be used to distinguish CMM's characteristics, such as shape, size, texture, section, ...
Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine [0.03%]
基于中药多糖的阿尔茨海默病治疗研究进展
Qin Liu,Shun-Chun Wang,Kan Ding
Qin Liu
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have been approved for the AD treatm...
Metabolomics coupled with similarity analysis advances the elucidation of the cold/hot properties of traditional Chinese medicines [0.03%]
结合相似性分析的代谢组学推进了对中药寒热性的阐释研究
Yan Jia,Zheng-Zheng Zhang,Yu-Hai Wei et al.
Yan Jia et al.
It recently becomes an important and urgent mission for modern scientific research to identify and explain the theory of traditional Chinese medicine (TCM), which has been utilized in China for more than four millennia. Since few works have...
Preparative separation and quantitative determination of two kaurenoic acid isomers in root barks of Acanthopanax gracilistylus [0.03%]
粗毛甘草根皮中两种卡氏酮酸异构体的分离及定量测定
Xin-Xin Xie,Ze-Jing Jiang,Zhi-Hong Cheng et al.
Xin-Xin Xie et al.
The kaurenoic acid-type diterpenoids in Acanthopanacis Cortex have been reported to be the major active components. However, the diterpenoids are present as position isomers that exacerbate the challenges in obtaining standards compounds. L...
Biotransformation of quercetin by Gliocladium deliquescens NRRL 1086 [0.03%]
齐墩果酸通过Gliocladium deliquescens NRRL 1086的生物转化
Jia-Qi Xu,Ni Fan,Bo-Yang Yu et al.
Jia-Qi Xu et al.
With an attempt to synthesize high-value isoquercitrin (quercetin-3-O-β-D-glucopyranoside), we carried out the biotransformation of quercetin (1) by Gliocladium deliquescens NRRL 1086. Along with the aimed product quercetin 3-O-β-D-glycos...
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury [0.03%]
假茂茎冬青抗高血压保护内皮细胞损伤的血管效应
Yue-Hua Jiang,Jin-Hao Guo,Sai Wu et al.
Yue-Hua Jiang et al.
Angiotensin II (Ang II) is involved in endothelium injury during the development of hypertension. Tribulus terrestris (TT) is used to treat hypertension, arteriosclerosis, and post-stroke syndrome in China. The present study aimed to determ...
Effects of ethanol extract of Bombax ceiba leaves and its main constituent mangiferin on diabetic nephropathy in mice [0.03%]
刺桐叶提取物及其主要成分芒果苷对糖尿病小鼠肾损伤的保护作用及机制研究
Guang-Kai Xu,Chen-Yu Sun,Xiao-Ying Qin et al.
Guang-Kai Xu et al.
The present study was designed to explore the mechanism by which ethanol extract of Bombax ceiba leaves (BCE) and its main constituent mangiferin (MGF) affect diabetic nephropathy by combating oxidative stress. Oral administration of BCE an...