Progress in active compounds effective on ulcerative colitis from Chinese medicines [0.03%]
有效治疗溃疡性结肠炎的中药活性成分研究进展
Si-Yu Cao,Sheng-Jie Ye,Wei-Wei Wang et al.
Si-Yu Cao et al.
Ulcerative colitis (UC), a chronic inflammatory disease affecting the colon, has a rising incidence worldwide. The known pathogenesis is multifactorial and involves genetic predisposition, epithelial barrier defects, dysregulated immune res...
Romipeptides A and B, two new romidepsin derivatives isolated from Chromobacterium violaceum No.968 and their antitumor activities in vitro [0.03%]
来源于 Chromobacterium violaceum No. 968 的两条新环霉素肽 Romipeptide A 和 Romipeptide B及其体外抗肿瘤活性研究
Lei Xiong,Chang-Fa Chen,Tao-Ling Min et al.
Lei Xiong et al.
Romipeptides A and B (1 and 2), two new romidepsin derivatives, and three known compounds, chromopeptide A (3), romidepsin (4) and valine-leucine dipeptide (5) were isolated from the fermentation broth of Chromobacterium violaceum No. 968. ...
Peptides and polyketides isolated from the marine sponge-derived fungus Aspergillus terreus SCSIO 41008 [0.03%]
来源于海洋海绵相关真菌Aspergillus terreus SCSIO 41008的多肽和聚酮类化合物
Xiao-Wei Luo,Yun Lin,Yong-Jun Lu et al.
Xiao-Wei Luo et al.
Two new isomeric modified tripeptides, aspergillamides C and D (compounds 1 and 2), together with fifteen known compounds (compounds 3-17), were obtained from the marine sponge-derived fungus Aspergillus terreus SCSIO 41008. The structures ...
Duo Cao,Li-Qing Wang,Xiao-Min Han et al.
Duo Cao et al.
In the present study, two new acetylene conjugate compounds, dibutyl (2Z, 6Z)-octa-2, 6-dien-4-yne dioate (1), and dibutyl (2E, 6E)- octa-2, 6-dien-4-yne dioate (2), were isolated from the dry stem leaves of Viscum album, along with nine kn...
Transcriptomic analysis in Anemone flaccida rhizomes reveals ancillary pathway for triterpene saponins biosynthesis and differential responsiveness to phytohormones [0.03%]
天麻根茎转录组分析揭示了三萜皂苷生物合成的辅助途径及其对植物激素的差异响应性
Guo-Yan Mo,Fang Huang,Yin Fang et al.
Guo-Yan Mo et al.
Anemone flaccida Fr. Schmidt is a perennial medicinal herb that contains pentacyclic triterpenoid saponins as the major bioactive constituents. In China, the rhizomes are used as treatments for a variety of ailments including arthritis. How...
Hesperetin derivative-12 (HDND-12) regulates macrophage polarization by modulating JAK2/STAT3 signaling pathway [0.03%]
橘皮素衍生物12通过调节JAK2/STAT3信号转导通路调控巨噬细胞极化
Ling-Na Kong,Xiang Lin,Cheng Huang et al.
Ling-Na Kong et al.
Macrophages show significant heterogeneity in function and phenotype, which could shift into different populations of cells in response to exposure to various micro-environmental signals. These changes, also termed as macrophage polarizatio...
Characteristics of the traditional Liu-Wei-Di-Huang prescription reassessed in modern pharmacology [0.03%]
从现代药理学角度重新评估传统六味地黄方的特色
Xiao-Rui Cheng,Chun-Hui Qi,Tong-Xing Wang et al.
Xiao-Rui Cheng et al.
Liu-Wei-Di-Huang (LW) is a Yin nourishing and kidney tonifying prescription in traditional Chinese medicine with promising pharmacological characteristics that can be further exploited and developed in modern medicine. We provide a comprehe...
Xiao-Dan MEIm,Yan-Feng Cao,Yan-Yun Che et al.
Xiao-Dan MEIm et al.
Danshen, the dried root or rhizome of Salvia miltiorrhiza Bge., is a traditional and folk medicine in Asian countries, especially in China and Japan. In this review, we summarized the recent researches of Danshen in traditional uses and pre...
Potential protective effects of red yeast rice in endothelial function against atherosclerotic cardiovascular disease [0.03%]
红曲米对动脉粥样硬化性心血管疾病内皮功能保护作用的潜在效果
Shu-Jun Feng,Zhi-Han Tang,Ying Wang et al.
Shu-Jun Feng et al.
Atherosclerotic cardiovascular disease (ASCVD) is the deadliest disease in the world, with endothelial injury occurring throughout the course of the disease. Therefore, improvement in endothelial function is of essential importance in the p...
Yi Lv,Kwok-Fai So,Nai-Kei Wong et al.
Yi Lv et al.
While most types of malignancies remain recalcitrant to treatment, application of natural products or their analogs in daily life has offered some hopes as an effective prophylaxis against cancer onset and progression in the past decades. E...