Modified Da-chai-hu Decoction regulates the expression of occludin and NF-κB to alleviate organ injury in severe acute pancreatitis rats [0.03%]
modified da-chai-hu decoction调节occludin和NF-κB的表达以缓解急性重症胰腺炎大鼠器官损伤
Guang Zhao,Yu-Zhen Zhuo,Li-Hua Cui et al.
Guang Zhao et al.
Modified Da-chai-hu Decoction (MDD), a traditional Chinese medicinal formulation, which was empirically generated from Da-chai-hu decoction, has been utilized to treat severe acute pancreatitis (SAP) for decades. The aim of the present stud...
Umbelliferone ameliorates renal function in diabetic nephropathy rats through regulating inflammation and TLR/NF-κB pathway [0.03%]
伞形茋甲素通过调节炎症和TLR/ NF- κ B通路改善糖尿病肾病大鼠的肾功能
Han-Qing Wang,Sha-Sha Wang,Kuok Chiufai et al.
Han-Qing Wang et al.
Diabetic nephropathy (DN) is a leading cause of renal failure, contributing to severe morbidity and mortality in diabetic patients. Umbelliferae (Umb) has been well characterized to exert protective effects in diabetes. However, the action ...
Rapid identification of Dendrobium officinale using Loop-Mediated Isothermal Amplification (LAMP) method [0.03%]
利用环介导等温扩增技术（LAMP）快速鉴别石斛伪品真品中的金钗石斛种质资源研究
Lu Yang,Wen-Ru Wu,Hua Zhou et al.
Lu Yang et al.
Dendrobium officinale is not only an ornamental plant, but also a valuable medicinal herb that is widely used in traditional Chinese medicine. However, distinguishing D. officinale from other Dendrobium species is usually a difficult task. ...
A brief history of artemisinin: Modes of action and mechanisms of resistance [0.03%]
青蒿素的简史——作用机制和耐药性模式
Feng Lu,Xin-Long He,Culleton Richard et al.
Feng Lu et al.
The cornerstone of antimalarial treatment, artemisinin, has reduced malaria associated morbidity and mortality worldwide. However, Plasmodium falciparum parasites with reduced sensitivity to artemisinin have emerged, and this threatens mala...
Metabolomics and its application in the treatment of coronary heart disease with traditional Chinese medicine [0.03%]
代谢组学及其在中医药治疗冠心病中应用的研究进展
Gao-Song Wu,Hou-Kai Li,Wei-Dong Zhang
Gao-Song Wu
Traditional Chinese Medicine (TCM) is the treasure of Chinese Nation and gained the gradual acceptance of the international community. However, the methods and theories of TCM understanding of diseases are lack of appropriate modern scienti...
Rapid discovery and identification of the anti-inflammatory constituents in Zhi-Shi-Zhi-Zi-Chi-Tang [0.03%]
栀子豉汤抗炎成分的快速发现与鉴定
Hai-Qiang Wang,Yun-Xiang Zhu,Yi-Ning Liu et al.
Hai-Qiang Wang et al.
The anti-inflammatory active ingredients of Zhi-Shi-Zhi-Zi-Chi-Tang (ZSZZCT), a traditional Chinese medicine formula, were predicted and identified using an approach based on activity index, LC-MS, semi-preparative LC and NMR. Firstly, the ...
Xiu-Qing Song,Jun-Sheng Zhang,Shu-Juan Yu et al.
Xiu-Qing Song et al.
Four new octadecanoid derivatives (1-4) including a pair of enantiomers (1/2), along with 12 known analogues (5-16), were isolatedfrom the seeds of Ipomoea nil. Their structures were determined by detailed spectroscopic analyses and compari...
Jatrogricaine A: a new diterpenoid with a 5/6/6/4 carbon ring system from the stems of Jatropha podagrica [0.03%]
来自大戟科植物的大戟 podagrica 茎中的新倍半萜类化合物 jatrogricaine A
Lin Chen,Jia-Luo Huang,Lei Zhang et al.
Lin Chen et al.
Jatrogricaine A (1), a new diterpenoid possessing a 5/6/6/4 carbon ring system, together with eight known diterpenoids (2-9) were isolated from the stems of Jatropha podagrica. Their structures were elucidated by extensive spectroscopic met...
Eight new cytotoxic annonaceous acetogenins from the seeds of Annona squamosa [0.03%]
尖喙木果实中的八个新的细胞毒性的糖苷类化合物
Cheng-Yao Ma,Jia-Hui Lu,Xiang Li et al.
Cheng-Yao Ma et al.
Eight new annonaceous acetogenins, squamotin A-D (1-4), annosquatin IV-V (5 and 6), muricin O (7) and squamosten B (8), together with four known ones (9-12) were isolated from the seeds of Annona squamosa. Their structures were elucidated b...
A novel approach based on metabolomics coupled with network pharmacology to explain the effect mechanisms of Danggui Buxue Tang in anaemia [0.03%]
基于代谢组学和网络药理学耦合的当归补血汤治疗贫血作用机制阐释的新思路
Yong-Li Hua,Qi Ma,Zi-Wen Yuan et al.
Yong-Li Hua et al.
Danggui Buxue Tang (DBT) is a famous Chinese medicinal decoction. Mechanism of DBT action is wide ranging and unclear. Exploring new ways of treatment with DBT is useful. Sprague-Dawley(SD) rats were randomly divided into 3 groups including...