Mei-Yu Lin,Zhong-Lan Yuan,Dan-Dan Hu et al.
Mei-Yu Lin et al.
Loureirin A is a major active component of Draconis sanguis, a traditional Chinese medicine. This work aimed to investigate the activity of loureirin A against Candida albicans biofilms. 2, 3-Bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazo...
Investigation into perturbed nucleoside metabolism and cell cycle for elucidating the cytotoxicity effect of resveratrol on human lung adenocarcinoma epithelial cells [0.03%]
通过探讨白藜芦醇对人类肺腺癌上皮细胞毒性作用来探究核苷代谢及细胞周期紊乱的研究
Zheng Li,Qian-Qian Chen,Christopher Wai Kei Lam et al.
Zheng Li et al.
In an effort to understand the molecular events contributing to the cytotoxicity activity of resveratrol (RSV), we investigated its effects on human lung adenocarcinoma epithelial cell line A549 at different concentrations. Cellular nucleos...
Dendrobium sonia polysaccharide regulates immunity and restores the dysbiosis of the gut microbiota of the cyclophosphamide-induced immunosuppressed mice [0.03%]
石斛 Sonia 多糖可调节免疫力并恢复免疫抑制小鼠肠道菌群失调的状态
Wei Liu,Ran Yan,Liang Zhang
Wei Liu
To recognize the potential medicinal value of the Dendrobium sonia, polysaccharide (DSP) was extracted, purified, and investigated for its immunomodulatory activity. In vitro, DSP was shown to enhance the viability (MTT assay) and phagocyto...
A novel protease-activated receptor 1 inhibitor from the leech Whitmania pigra [0.03%]
源于中华水蛭蛋白酶激活受体1新型抑制剂的研究
Shen-Hong Ren,Zhao-Jun Liu,Yuan Cao et al.
Shen-Hong Ren et al.
Whitmania pigra has been used as a traditional Chinese medicine (TCM) for promoting blood circulation, alleviating blood coagulation, activating meridians and relieving stasis for several hundred years. However, the therapeutic components o...
Miao Liu,Xi-Wen Li,Bao-Sheng Liao et al.
Miao Liu et al.
The aim is to select a universal DNA barcode for identifying all poisonous medicinal plants in Chinese pharmacopoeia and their poisonous related species or adulterants. We chose 4 commonly used regions as candidate DNA barcodes (ITS2, psbA-...
Differential expression of the TwHMGS gene and its effect on triptolide biosynthesis in Tripterygium wilfordii [0.03%]
粗毛戟叶苷脱氢异构酶基因的差异表达及其对青藤碱生物合成的影响
Yu-Ru Tong,Yi-Feng Zhang,Yu-Jun Zhao et al.
Yu-Ru Tong et al.
3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is the first committed enzyme in the MVA pathway and involved in the biosynthesis of terpenes in Tripterygium wilfordii. The full-length cDNA and a 515 bp RNAi target fragment of TwHMGS were li...
Microcos paniculata: a review on its botany, traditional uses, phytochemistry and pharmacology [0.03%]
微蘚的植物学、传统应用、次生代谢产物和药理作用研究进展
Ying-Qun Jiang,E-Hu Liu
Ying-Qun Jiang
The shrub Microcos paniulata (MPL; Tiliaceae), distributed in south China, south and southeast Asia, yields a phytomedicine used to treat heat stroke, fever, dyspepsia, diarrhea, insect bites and jaundice. Phytochemical investigations on di...
Hao Han,Zhi-Kai Guo,Bo Zhang et al.
Hao Han et al.
Three new phenazine-type compounds, named phenazines SA-SC (1-3), together with four new natural products (4-7), were isolated from the fermentation broth of an earwig-associated Streptomyces sp. NA04227. The structures of these compounds w...
Withaminimas A-F, six withanolides with potential anti-inflammatory activity from Physalis minima [0.03%]
Physalis minima的六种具有潜在抗炎活性的_WITHAMINIMAS_A-F
Shan-Shan Wei,Cai-Yun Gao,Rui-Jun Li et al.
Shan-Shan Wei et al.
Withaminimas A-F (1-6), six new withaphysalin-type withanolides were isolated from the aerial parts of Physalis minima L.. The structures of these compounds were elucidated through a variety of spectroscopic techniques including HR-MS, NMR,...
Cardamine komarovii flower extract reduces lipopolysaccharide-induced acute lung injury by inhibiting MyD88/TRIF signaling pathways [0.03%]
卡罗氏独活花提取物通过抑制MyD88 / TRIF信号途径减少脂多糖诱导的急性肺损伤
Qi Chen,Ke-Xin Zhang,Tai-Yuan Li et al.
Qi Chen et al.
In the present study, we investigated anti-inflammatory effect of Cardamine komarovii flower (CKF) on lipopolysaccharide (LPS)-induced acute lung injury (ALI). We determined the effect of CKF methanolic extracts on LPS-induced pro-inflammat...