Purification, structure characterization and antioxidant activity of polysaccharides from Saposhnikovia divaricata [0.03%]
防风多糖的提取纯化、结构鉴定及其抗氧化活性研究
Yao Meng,Lin Yi,Lei Chen et al.
Yao Meng et al.
Polysaccharide from traditional Chinese herb, Saposhnikovia divaricata (Turcz.) Schischk. (SD) was extracted, fractionated and characterized in this work. Four fractions were prepared. Their molecular weight, monosaccharide compositions, li...
Abilova Zhamilya,Jie Yuan,Jenis Janar et al.
Abilova Zhamilya et al.
One new dimeric (1) and two monomeric sesquiterpene lactones (5 and 13), together with 10 known compounds (2-4, 6-12), were isolated from Artemisia heptapotamica collected in Almaty region of Kazakhstan. All compounds were isolated from thi...
Steroidal constituents from Helleborus thibetanus and their cytotoxicities [0.03%]
西藏铁线莲中的甾体类成分及其体外抗肿瘤活性研究
Yu-Ze Li,Hua-Wei Zhang,Hao Fan et al.
Yu-Ze Li et al.
Thibetanosides E-H (1-4), four new steroidal constituents including three rare sulfonates (2-4), were isolated from the roots and rhizomes of Helleborus thibetanus, together with nine known steroidal compounds (5-13). Their structures were ...
Inhibitory effects of polyphyllins I and VII on human cisplatin-resistant NSCLC via p53 upregulation and CIP2A/AKT/mTOR signaling axis inhibition [0.03%]
鹅掌管仲素I和VII通过上调p53蛋白及抑制CIP2A/AKT/mTOR信号轴来抑制人顺铂耐药非小细胞肺癌的作用
Fei-Fei Feng,Peng Cheng,Chao Sun et al.
Fei-Fei Feng et al.
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a human oncoprotein that is overexpressed in multiple kinds of cancers including non-small cell lung cancer (NSCLC). CIP2A plays an 'oncogenic nexus' to participate in the tumorigenes...
Pilose antler aqueous extract promotes the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells by stimulating the BMP-2/Smad1, 5/Runx2 signaling pathway [0.03%]
鹿角胶通过激活骨形态蛋白2/Smad1、5/Runx2信号通路促进骨髓间充质干细胞增殖和成骨分化
Cong Ren,Wei Gong,Feng Li et al.
Cong Ren et al.
Peptides from Pilose antler aqueous extract (PAAE) have been shown to stimulate the proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs). However, the underlying molecular mechanisms are not well understood. Here,...
YQWY decoction reverses cardiac hypertrophy induced by TAC through inhibiting GATA4 phosphorylation and MAPKs [0.03%]
补心氏汤通过抑制GATA4磷酸化和MAPKs逆转TAC诱导的心室重构
Jing-Jing Huang,Yong Xie,He Li et al.
Jing-Jing Huang et al.
To investigate the effect of Yiqi Wenyang (YQWY) decoction on reversing cardiac hypertrophy induced by the transverse aortic constriction (TAC). Wistar rats aged 7-8 weeks were subjected to TAC surgery and then randomly divided into 4 group...
DNA barcoding and rapid identification of the precious herb Herba Anoectochili [0.03%]
基于DNA条形码技术的穿心莲快速鉴定方法研究
Shuai-Jun Hu,Hao-Yu Hu,Han Gao et al.
Shuai-Jun Hu et al.
Herba Anoectochili is a commonly used medicinal material. However, its adulteration is a serious concern. Due to the similar morphological characteristics of Herba Anoectochili and its adulterants, traditional identification techniques ofte...
The prognostic impact of traditional Chinese medicine monomers on tumor-associated macrophages in non-small cell lung cancer [0.03%]
中药单体对非小细胞肺癌肿瘤相关巨噬细胞预后影响的研究
Liang-Qin Wan,Yan Tan,Miao Jiang et al.
Liang-Qin Wan et al.
Non-small cell lung cancer (NSCLC) accounts for 80%-85% of all lung malignancies and good diagnosis and prognosis of NSCLC are critical to the increase of its survival rate. Tumor-associated macrophages (TAM) abundantly present in numerous ...
Therapeutic effects of garlic in cardiovascular atherosclerotic disease [0.03%]
大蒜在心血管动脉粥样硬化性疾病治疗中的作用
Igor A Sobenin,Veronika A Myasoedova,Maria I Iltchuk et al.
Igor A Sobenin et al.
Garlic (Allium sativum) is a widely known medicinal plant, potential of which remains to be fully evaluated. Its wide-range beneficial effects appear to be relevant for treatment and prevention of atherosclerosis and related diseases. It is...