Three new isocoumarin derivatives from the mangrove endophytic fungus Penicillium sp. YYSJ-3 [0.03%]
三株互生固氮菌异香豆素衍生物的研究
Pei Qiu,Run-Lin Cai,Lin Li et al.
Pei Qiu et al.
Three new isocoumarin derivatives, (S)-6,8-dihydroxy-5-(methoxymethyl)-3,7-dimethylisochroman-1-one (1), (S)-6,8-dihydroxy-3,5,7-trimethyl-isochroman-1-one (2) and (R)-2-chloro-3-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl) propyl acetate...
Four new steroids from the marine soft coral-derived fungus Penicillium sp. SCSIO41201 [0.03%]
由海洋软珊瑚分离出的真菌Penicillium sp. SCSIO41201中新 steroid 类化合物的研究
Jie-Yi Long,Jun-Feng Wang,Sheng-Rong Liao et al.
Jie-Yi Long et al.
Penicildiones A-D (1-4), four new steroids derivatives together with three known compounds including 16α-methylpregna-17α,19-dihydroxy-(9,11)-epoxy-4-ene-3,18-dione-20-acetoxy (5), stachybotrylactone B (6) and stachybotrin (7) were isolat...
A new iron(III) chelator of coprogen-type siderophore from the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059 [0.03%]
来源于深海内生真菌Mycosphaerella sp. SCSIO Z059的新铁载体类似物抗生素分子Coprogrin A
Zhong-Hui Huang,Xiao Liang,Shu-Hua Qi
Zhong-Hui Huang
Mycosphazine A (1), a new iron(III) chelator of coprogen-type siderophore, and mycosphamide A (2), a new cyclic amide benzoate, together with six known aryl amides (3-8), were isolated from the fermentation broth of the deep-sea-derived fun...
The importance of researches on the fungal bioactive secondary metabolites in developing the comprehensive health industry [0.03%]
真菌次生代谢产物研究在大健康产业发展中的作用与前景展望
Guo-Dong Chen,Dan Hu,Hao Gao et al.
Guo-Dong Chen et al.
Pharmacokinetic interaction of Forsythia suspensa extract and azithromycin injection after single and co-intravenous administration in rats [0.03%]
单剂量及联合静脉给药连翘提取物和盐酸左氧氟沙星在大鼠体内相互作用的药动学研究
Xin-Gang Li,Jian Ni,Su Shen et al.
Xin-Gang Li et al.
Azithromycin and Chinese medicine forsythia are often used together to treat pediatric mycoplasma infections in China. We aimed to investigate the pharmacokinetic interaction of Forsythia suspensa extract and azithromycin after single and c...
Shenfu injection attenuates lipopolysaccharide-induced myocardial inflammation and apoptosis in rats [0.03%]
Shenfu注射液减缓脂多糖致大鼠心肌炎症及凋亡
Rui-Juan Chen,Qing-Lin Rui,Qiong Wang et al.
Rui-Juan Chen et al.
Shenfu injection (SFI), a Chinese medicinal product, shows potent efficacy in treating sepsis. The aim of the present study was to clarify the protective effects of SFI against lipopolysaccharide (LPS)-induced myocardial inflammation and ap...
Construction and application of carbohydrate microarrays to detect foodborne bacteria [0.03%]
用于检测食源性细菌的糖基微阵列的构建及应用
Jing Hu,Yong Xiao,Shu-An Shao et al.
Jing Hu et al.
The rapid detection of pathogenic bacteria is vital for the prevention of outbreaks of infectious diseases, including infections by the common foodborne bacteria E.coli and Salmonella Carbohydrate microarrays have been developed as a powerf...
Targeted bile acids and gut microbiome profiles reveal the hepato-protective effect of WZ tablet (Schisandra sphenanthera extract) against LCA-induced cholestasis [0.03%]
靶向胆汁酸和肠道微生物组谱型揭示了五味子乙素(WZ片)对LCA致肝胆疾病的保护作用
Dong-Shun Li,Quan-Fei Huang,Li-Huan Guan et al.
Dong-Shun Li et al.
Cholestasis is caused by the obstacle of bile formation or secretion and can develop into severe liver diseases. We previously reported the ethanol extract of Schisandra sphenanthera (Wuzhi tablet, WZ) can significantly protect against lith...
Traditional Chinese Medicine: an effective treatment for 2019 novel coronavirus pneumonia (NCP) [0.03%]
中医药防治新型冠状病毒肺炎的优势抢先看
Hong-Zhi DU,Xiao-Ying Hou,Yu-Huan Miao et al.
Hong-Zhi DU et al.
The novel coronavirus pneumonia broke out in 2019 and spread rapidly. In 30 different countries, there are over seventy thousand patients have been diagnosed in total. Therefore, it is urgent to develop the effective program to prevent and ...
Organic anion transporter 1 and 3 contribute to traditional Chinese medicine-induced nephrotoxicity [0.03%]
有机阴离子转运蛋白1和3参与中药所致肾毒性
Qing-Qing Shen,Jing-Jing Wang,Debmalya Roy et al.
Qing-Qing Shen et al.
With the internationally growing popularity of traditional Chinese medicine (TCM), TCM-induced nephropathy has attracted public attention. Minimizing this toxicity is an important issue for future research. Typical nephrotoxic TCM drugs suc...