The antibacterial activity of Berberis heteropoda Schrenk and its effect on irritable bowel syndrome in rats [0.03%]
刺柏的抗菌活性及其对大鼠肠易激综合征的影响
Li Li,Hui-Min Zhu,Qi Yan et al.
Li Li et al.
The dried roots of Berberis heteropoda Schrenk have traditionally been used to treat acute gastroenteritis and dysentery. The aim of this study was to confirm the antibacterial activity of an extract of Berberis heteropoda Schrenk rootin vi...
Cordycepin inhibits pancreatic cancer cell growth in vitro and in vivo via targeting FGFR2 and blocking ERK signaling [0.03%]
虫草素通过靶向FGFR2和阻断ERK信号抑制胰腺癌细胞的生长
Xue-Ying Li,Homng Tao,Can Jin et al.
Xue-Ying Li et al.
Cordycepin (3'-deoxyadenosine) from Cordyceps militaris has been reported to have anti-tumor effects. However, the molecular target and mechanism underlying cordycepin impeding pancreatic cancer cell growth in vitro and in vivo remain vague...
A review of the phytochemistry and pharmacological activities of Ephedra herb [0.03%]
麻黄属植物的化学和药理学活性研究进展综述
Shuang-Man Miao,Qi Zhang,Xiao-Bao Bi et al.
Shuang-Man Miao et al.
Ephedra herb is a traditional Chinese medicine with a long history. Conventionally, it was used as a folk phytomedicine in many ancient medical books and traditional prescriptions. Up to date, a variety of specific ingredients have been fou...
Osthole attenuates pulmonary arterial hypertension by the regulation of sphingosine 1-phosphate in rats [0.03%]
淫羊藿苷通过调节鞘氨醇-1-磷酸减轻大鼠肺动脉高压的作用研究
Li Yao,Yu-Xia Yang,Hui Cao et al.
Li Yao et al.
Osthole is observed to have the capacity to treat pulmonary arterial hypertension (PAH) in rats, but molecular mechanism is still unknown. The present study aims to discover therapeutic targets and explore therapeutic mechanism of osthole a...
Prodrugs of hydrogen sulfide and related sulfur species: recent development [0.03%]
硫化氢及类似硫物质的前药研究进展
Zheng-Nan Yuan,Yue-Qin Zheng,Bing-He Wang
Zheng-Nan Yuan
Hydrogen sulfide (H2S) is commonly referred to as the third gasotransmitter with firmly established physiological roles. Prodrug approaches have been broadly applied to deliver H2S for various applications and mechanistic studies. Since S-p...
Xiao-Xiao Yang,Bo-Wen Ke,Wen Lu et al.
Xiao-Xiao Yang et al.
Carbon monoxide (CO) as one of the three important endogenously produced signaling molecules, termed as "gasotransmitter," has emerged as a promising therapeutic agent for treating various inflammation and cellular-stress related diseases. ...
Yu-Jie Mao,Jian-Bing Wu,Ze-Qiu Yang et al.
Yu-Jie Mao et al.
Glaucoma is a disease that causes irreversible blindness. Reducing intraocular pressure (IOP) is the main treatment at present. Nitric oxide (NO), an endogenous gas signaling molecule, can increase aqueous humor outflow facility, inhibit aq...
Zhang-Jian Huang,Bing-He Wang
Zhang-Jian Huang
Si-Xian Wang,Rui-Lin Zhao,Cui Guo et al.
Si-Xian Wang et al.
Two new meroterpenoid compounds (1 and 2) together with five known meroterpenoid derivatives (3-7) were isolated from solid culture of mushroom Panus lecomtei. The structures of new compounds were confirmed by the analysis of NMR and HR-ESI...
Caryophyllene-type sesquiterpenoids and α-furanones from the plant endophytic fungus Pestalotiopsis theae [0.03%]
产于茶树的内生真菌Pestalotiopsis theae中的蒈烷型倍半萜及α-呋喃酮类化合物
Long-Fang Guo,Gao-Ran Liu,Ling Liu
Long-Fang Guo
Two new caryophyllene-type sesquiterpenoids, pestathenols A (1) and B (2) and one new α-furanone, pestatheranone A (6), along with five known compounds (3-5, 7 and 8) have been isolated from the crude extract of the plant endophytic fungus...