Design, synthesis, and biological evaluation of ligustrazine/resveratrol hybrids as potential anti-ischemic stroke agents [0.03%]
作为潜在抗缺血性脑卒中试剂的刺芒柄花素/白藜芦醇杂合分子的设计、合成及生物活性评价
Yin-Qiu Zhang,Jian-Bing Wu,Wei Yin et al.
Yin-Qiu Zhang et al.
To search for potent anti-ischemic stroke agents, a series of tetramethylpyrazine (TMP)/resveratrol (RES) hybrids 6a-t were designed and synthesized. These hybrids inhibited adenosine diphosphate (ADP)- or arachidonic acid (AA)-induced plat...
Total synthesis of D-glycero-D-mannno-heptose 1β, 7-bisphosphate with 3-O-amyl amine linker and its monophosphate derivative [0.03%]
具有3-O-氨甲基键的D-甘油-D-赤果糖-1β，7-二磷酸及其单酯衍生物的全合成
Xiao-Peng Zou,Chun-Jun Qin,Jing Hu et al.
Xiao-Peng Zou et al.
D-Glycero-D-mannno-heptose 1β, 7-bisphosphate (HBPβ) is an important intermediate for constructing the core structure of Gram-negative bacterial lipopolysaccharides and was reported as a pathogen-associated molecular pattern (PAMP) that r...
Tao-Hong-Si-Wu Decoction promotes angiogenesis after cerebral ischaemia in rats via platelet microparticles [0.03%]
桃红四物汤通过血小板微粒促进脑缺血大鼠的血管生成
Fang-Fang Chen,Meng-Meng Wang,Wen-Wen Xia et al.
Fang-Fang Chen et al.
Platelet microparticles (PMPs) are membrane particles derived from the platelet membrane that enter into the blood circulation. We sought to explore the therapeutic effects of Tao-Hong-Si-Wu Decoction (THSWD) on angiogenesis in a rat model ...
Early intervention with Di-Dang Decoction prevents macrovascular fibrosis in diabetic rats by regulating the TGF-β1/Smad signalling pathway [0.03%]
迪黛汤早期干预通过调控TGF-β1/Smad信号通路预防糖尿病大鼠的宏血管纤维化
Sheng-Nan Zhou,Jian Zhang,Qiu-Yue Ren et al.
Sheng-Nan Zhou et al.
Macroangiopathy is a complication of Type II Diabetes Mellitus (T2DM), which is mainly caused by fibrosis of blood vessels. Using T2DM rat models, we investigated whether the traditional Chinese medicine, Di-Dang Decoction (DDD), exhibited ...
Genome-wide identification of abscisic acid (ABA) receptor pyrabactin resistance 1-like protein (PYL) family members and expression analysis of PYL genes in response to different concentrations of ABA stress in Glycyrrhiza uralensis [0.03%]
甘草中脱落酸（ABA）受体Pyrabactin抗性1样蛋白(PYL)家族的全基因组鉴定及不同浓度ABA胁迫下PYL基因表达分析
Ying-Xian Cui,Zhi-Chao Xu,Xin-Lian Chen et al.
Ying-Xian Cui et al.
As abscisic acid (ABA) receptor, the pyrabactin resistance 1-like (PYR/PYL) protein (named PYL for simplicity) plays an important part to unveil the signal transduction of ABA and its regulatory mechanisms. Glycyrrhiza uralensis, a drought-...
Identification of medicinal plants within the Apocynaceae family using ITS2 and psbA-trnH barcodes [0.03%]
利用ITS2和psbA-trnH条形码对夹竹桃科药用植物进行鉴定
Ya-Na Lv,Chun-Yong Yang,Lin-Chun Shi et al.
Ya-Na Lv et al.
To ensure the safety of medications, it is vital to accurately authenticate species of the Apocynaceae family, which is rich in poisonous medicinal plants. We identified Apocynaceae species by using nuclear internal transcribed spacer 2 (IT...
Genome-wide identification and analysis of AP2/ERF transcription factors related to camptothecin biosynthesis in Camptotheca acuminata [0.03%]
长春花中与喜树碱生物合成相关AP2 / ERF转录因子的全基因组识别和分析
Ya-Ting Hu,Zhi-Chao Xu,Ya Tian et al.
Ya-Ting Hu et al.
Camptotheca acuminata produces camptothecin (CPT), a monoterpene indole alkaloid (MIA) that is widely used in the treatment of lung, colorectal, cervical, and ovarian cancers. Its biosynthesis pathway has attracted significant attention, bu...
Molecular structure and phylogenetic analyses of the complete chloroplast genomes of three original species of Pyrrosiae Folium [0.03%]
三种原生淫羊藿属植物的叶完整叶绿体基因组分子结构及系统发育分析
Chu-Hong Yang,Xia Liu,Ying-Xian Cui et al.
Chu-Hong Yang et al.
Pyrrosia petiolosa, Pyrrosia lingua and Pyrrosia sheareri are recorded as original plants of Pyrrosiae Folium (PF) and commonly used as Chinese herbal medicines. Due to the similar morphological features of PF and its adulterants, common DN...
Complete chloroplast genome of Salvia plebeia: organization, specific barcode and phylogenetic analysis [0.03%]
香茶菜完整叶绿体基因组的组织、特定条形码和系统发育分析
Ning Cui,Bao-Sheng Liao,Cong-Lian Liang et al.
Ning Cui et al.
Salvia plebeia has been in use as traditional Chinese medicine (TCM) for more than 500 years. In this study, the complete chloroplast (cp) genome of S. plebeia was sequenced, assembled and compared to those of other five published Salvia cp...
Xi-Wen Li,Shi-Lin Chen
Xi-Wen Li