Rhodiola crenulata extract decreases fatty acid oxidation and autophagy to ameliorate pulmonary arterial hypertension by targeting inhibiton of acylcarnitine in rats [0.03%]
高山红景天提取物通过靶向抑制乙酰辅酶A改善肺动脉高压
Huan-Huan Ren,Zheng Niu,Rui Guo et al.
Huan-Huan Ren et al.
Pulmonary arterial hypertension (PAH) is a devastating pulmonary circulation disease lacking high-efficiency therapeutics. The present study aims to decipher the therapeutic mechanism of Rhodiola crenulata, a well-known traditional chinese ...
Mangiferin inhibited neuroinflammation through regulating microglial polarization and suppressing NF-κB, NLRP3 pathway [0.03%]
mango叶提取物 Mangiferin通过调节小胶质细胞极化及抑制NF-κB、NLRP3信号通路抑制神经炎症作用研究
Li-Yan Lei,Rui-Cheng Wang,Ya-Lei Pan et al.
Li-Yan Lei et al.
Inflammation plays important roles in the progress of neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. Microglia is responsible for the homeostasis of the central nervous system (CNS), and involved in the neu...
Effects of Huatan Jiangzhuo decoction on diet-induced hyperlipidemia and gene expressions in rats [0.03%]
化痰降浊汤对高脂饮食大鼠血脂及基因表达的影响
Qi Ren,Xiao-Qi Liu,Xiao-Wen Zhou et al.
Qi Ren et al.
Huatan Jiangzhuo decoction (HJD) is a combination of six traditional Chinese medicines that were used for lipid metabolism-related disorders, but its efficacy and underlying mechanisms have not been explored by modern research strategies. T...
Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos [0.03%]
植物代谢组学在探究两种杀虫剂对金银花综合性状影响中的应用研究
Hui-Qin Pan,Heng Zhou,Shui Miao et al.
Hui-Qin Pan et al.
Pesticides' overuse and misuse have been reported to induce ingredient variations in herbal medicine, which is now gaining attention in the medicinal field as a form of alternative medicine. To date, available studies on pesticide-induced i...
Triterpenoid saponins and phenylpropanoid glycoside from the roots of Ardisia crenata and their cytotoxic activities [0.03%]
石仙桃根的三萜皂苷和苯丙醇苷成分及其体外抗肿瘤活性研究
Ning-Ning Song,Lei-Min Yang,Min-Jie Zhang et al.
Ning-Ning Song et al.
Two new triterpenoid saponins, ardisicrenoside R and S (1 and 2), and one new phenylpropanoid glycoside, ardicrephenin (3), along with five known compounds (4-8), were isolated from roots of Ardisia crenata. Their structures were elucidated...
Polysaccharide from Astragalus membranaceus promotes the activation of human peripheral blood and mouse spleen dendritic cells [0.03%]
膜荚黄芪多糖对小鼠脾细胞和人外周血树突状细胞的活化作用
Seong-Min Lim,Hae-Bin Park,Jun-O Jin
Seong-Min Lim
Astragalus membranaceus (A. membranaceus) is a widely used traditional herb in China and Korea. A. membranaceus polysaccharides (AMP), which make up a major part of the root extract, have been shown to modulate immune modulations, especiall...
A 75 kDa glycoprotein isolated from Cudrania tricuspidata Bureau induces colonic epithelial proliferation and ameliorates mouse colitis induced by dextran sulfate sodium [0.03%]
刺槐果三叶止血收敛多糖蛋白诱导结肠上皮细胞增殖并改善DSS致小鼠结肠炎模型症状
Jeong-Bae Park,Do-Wan Kim,Kye-Taek Lim et al.
Jeong-Bae Park et al.
Cudrania tricuspidata Bureau (CTB), a species of the Moraceae plant, has been used as a bruise recovery treatment. This study aimed to determine whether the 75 kDa phytoglycoprotein extracted from CTB has a regulatory effect on the prolifer...
Effects of Bunao-Fuyuan decoction serum on proliferation and migration of vascular smooth muscle cells in atherosclerotic [0.03%]
补脑敷渊汤对动脉粥样硬化血管平滑肌细胞增殖和迁移的影响
Huan-Yu Guo,Zhen-Ya Lu,Bo Zhao et al.
Huan-Yu Guo et al.
Atherosclerosis (AS) is a chronic inflammatory disease, the main causes of which include abnormal lipid metabolism, endothelial injury, physical and chemical injury, hemodynamic injury, genetic factors and so on. These causes can lead to in...
Study on the action mechanism of Wuling Powder on treating osteoporosis based on network pharmacology [0.03%]
基于网络药理学的五灵脂治疗骨质疏松症作用机制研究
Hao-Nan Zhou,Hao-Yu Li,Wen-Hua Xu et al.
Hao-Nan Zhou et al.
Osteoporosis is a health problem to cause global concern. A lot of methods have been used to prevent and treat osteoporosis, but there is still a lack of effective treatment for osteoporosis owing to limited understanding of its mechanism. ...
Ying-Rong Leng,Mei-Hui Zhang,Jian-Guang Luo et al.
Ying-Rong Leng et al.
Nonalcoholic steatohepatitis (NASH) is a common clinical condition that can lead to advanced liver diseases. The mechanism of the diaease progression, which is lacking effective therapy, remains obsure. Therefore, there is a need to underst...