Ginsenoside Rb1 improves brain, lung, and intestinal barrier damage in middle cerebral artery occlusion/reperfusion (MCAO/R) micevia the PPARγ signaling pathway [0.03%]
红参皂苷Rb1通过PPARγ信号通路改善脑缺血再灌注损伤小鼠的血脑屏障、肠屏障和肺屏障损伤的作用研究
Lin-Jie Su,Yu-Chuan Ren,Zhuo Chen et al.
Lin-Jie Su et al.
Ischemic stroke causes brain inflammation and multi-organ injury, which is closely associated with the peroxisome proliferator-activated receptor-gamma (PPARγ) signaling pathway. Recent studies have indicated that ginsenoside Rb1 (GRb1) ca...
Deep chemical identification of phytoecdysteroids in Achyranthes bidentata Blume by UHPLC coupled with linear ion trap-Orbitrap mass spectrometry and targeted isolation [0.03%]
基于UHPLC线性离子阱-轨道阱高分辨质谱的虎杖中植物蜕皮甾酮类成分深度识别及靶向富集研究
Ying-Ying Wang,Jia-Yuan Li,Chang-Liang Yao et al.
Ying-Ying Wang et al.
Achyranthes bidentata Blume is widely used as a traditional Chinese medicine with the effects of nourishing the liver and kidneys and strengthening muscles and bones. In this work, a rapid and simple strategy was developed for characterizin...
Antiproliferative piperidine alkaloids from giant taro (Alocasia macrorrhiza) [0.03%]
巨型天南星中的抗增殖类生物碱化合物研究
Wei Gao,Yi Wang,Ru Wang et al.
Wei Gao et al.
The rhizome of giant taro (Alocasia macrorrhiza (L.) Schott), which is a highly adaptable wild plant, is a traditional Chinese herbal medicine. In the current study, the antiproliferative constituents of giant taro were investigated and six...
Four new diphenyl ether derivatives from a mangrove endophytic fungus Epicoccum sorghinum [0.03%]
Saccharides杂志发表宋宝安/陈祥贵团队糖生物化学研究进展
Jun-Jie Zhu,Qi-Sen Huang,Sheng-Quan Liu et al.
Jun-Jie Zhu et al.
Four new diphenyl ethers, named epicoccethers K-N (1-4), were purified from the fermentation medium of a fungus Epicoccum sorghinum derived from Myoporum bontioides, and identified through HR-ESI-MS and NMR spectral analysis. Except that co...
Molecular cloning and characterization of three phenylalanine ammonia-lyase genes from Schisandra chinensis [0.03%]
五味子三个苯氨酶基因的克隆与序列分析
San-Peng Fan,Wei Chen,Jiang-Chun Wei et al.
San-Peng Fan et al.
Phenylalanine ammonia-lyase (PAL), which catalyzes the conversion from L-phenylalanine to trans-cinnamic acid, is a well-known key enzyme and a connecting step between primary and secondary metabolisms in the phenylpropanoid biosynthetic pa...
The extract of Celtis choseniana Nakai alleviates testosterone-induced benign prostatic hyperplasia through inhibiting 5α reductase type 2 and the Akt/NF-κB/AR pathway [0.03%]
辽东白蜡树提取物通过抑制5α还原酶II和Akt/NF-κB/AR信号通路治疗睾酮诱导的良性前列腺增生
Geum-Lan Hong,Tae-Won Kim,Hui-Ju Lee et al.
Geum-Lan Hong et al.
Benign prostatic hyperplasia (BPH) is a chronic male disease characterized by the enlarged prostate. Celtis chosenianaNakai (C. choseniana) is medicinally used to alleviate pain, gastric disease, and lung abscess. In this study, the effect ...
Inhibition of Escherichia coli nitroreductase by the constituents in Syzygium aromaticum [0.03%]
肉桂树属芳香物质抑制大肠杆菌的硝基还原酶作用
Lu Chen,Xi Chen,Yue Bai et al.
Lu Chen et al.
Gut bacterial nitroreductases play an important role in reduction of various nitroaromatic compounds to the corresponding N-nitroso compounds, hydroxylamines or aromatic amines, most of which are carcinogenic and mutagenic agents. Inhibitio...
Jujuboside A inhibits oxidative stress damage and enhances immunomodulatory capacity of human umbilical cord mesenchymal stem cells through up-regulating IDO expression [0.03%]
绞股蓝皂苷A通过上调IDO表达抑制氧化应激损伤并增强人脐带间充质干细胞免疫调节能力
Ji-Cong Chen,Hong-He Xiao,Qiang Zhang et al.
Ji-Cong Chen et al.
Impaired immunomodulatory capacity and oxidative stress are the key factors limiting the effectiveness of mesenchymal stem cell transplantation therapy. The present study was aimed to investigate the effects of jujuboside A (JuA) on the pro...
Modern research thoughts and methods on bio-active components of TCM formulae [0.03%]
现代中药复方活性成分组学研究思想与方法学探析
Yu-Ping Tang,Ding-Qiao Xu,Shi-Jun Yue et al.
Yu-Ping Tang et al.
TCM formulae are the important guidances for clinical application of traditional Chinese medicines, which follow the principles of diagnosis and treatment in TCM. Elucidating the bio-active components of TCM formulae is the key to the moder...
Ascyrones A-E, type B bicyclic ployprenylated acylphloroglucinol derivatives from Hypericum ascyron [0.03%]
Hypericum ascyron中五种B型双环聚戊二烯基酰基茋酚衍生物(阿斯克龙因A～E)
Xin Deng,Jing Xia,Meng-Yu Qian et al.
Xin Deng et al.
Five new polycyclic polyprenylated acylphloroglucinols (1-5), ascyrones A-E, and four known compounds (6-9) were isolated from the aerial parts of Hypericum ascyron. All of the isolates containing a bicyclo[3.3.1]nonane-2,4,9-trione core an...