20(S)-ginsenoside Rh1 alleviates T2DM induced liver injury via the Akt/FOXO1 pathway [0.03%]
Ginsenoside Rh1通过Akt/FOXO1信号通路缓解T2DM诱导的肝损伤
Wen-Ya Su,Mei-Ling Fan,Ying Li et al.
Wen-Ya Su et al.
Diabetes-associated liver injury becomes a dominant hepatopathy, leading to hepatic failure worldwide. The current study was designed to evaluate the ameliorative effects of ginsenoside Rh1 (G-Rh1) on liver injury induced by T2DM. A T2DM mo...
Jujuboside A ameliorates tubulointerstitial fibrosis in diabetic mice through down-regulating the YY1/TGF-β1 signaling pathway [0.03%]
洛神花素A通过下调YY1/TGF-β1信号通路改善糖尿病小鼠的肾小管间质纤维化
Yang-Yang Liu,Lin Li,Bei Ji et al.
Yang-Yang Liu et al.
Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus, which is characterized in renal tubulointerstitial fibrosis (TIF). The current study was designed to investigate the protective effect of Jujuboside A (...
Probiotics with anti-type 2 diabetes mellitus properties: targets of polysaccharides from traditional Chinese medicine [0.03%]
具有抗2型糖尿病功能的益生菌：来自传统中药多糖的作用靶点
Lun Wu,Yue Gao,Yang Su et al.
Lun Wu et al.
Traditional Chinese medicine polysaccharides is a biologically active ingredient that is not easy to be digested. It is fermented by intestinal microflora to promote qualitative and selective changes in the composition of the intestinal mic...
Determination of ribose and phosphorus contents in Haemophilus influenzae type b capsular polysaccharide by a quantitative NMR method using a single internal standard [0.03%]
采用单一内标定量核磁共振法测定b型流感嗜血杆菌荚膜多糖中的核糖和磷含量
Chun-Jun Qin,Jing Hu,Wei Tong et al.
Chun-Jun Qin et al.
The ribose and phosphorus contents in Haemophilus influenzae type b (Hib) capsular polysaccharide (CPS) are two important chemical indexes for the development and quality control of Hib conjugate vaccine. A quantitative 1H- and 31P-NMR meth...
New antibacterial depsidones from an ant-derived fungus Spiromastix sp. MY-1 [0.03%]
一种蚂蚁来源真菌Spiromastix sp. MY-1的新型抗菌二苯乙烯类化合物
Zhi-Kai Guo,Wen-Yong Zhu,Li-Xing Zhao et al.
Zhi-Kai Guo et al.
Six new (1-6) and seven known depsidones (7-13) were isolated from the culture of an ant (Monomorium chinensis)-derived fungus Spiromastix sp. MY-1. Their structures were elucidated by extensive spectroscopic analysis including high resolut...
Integrative SMRT sequencing and ginsenoside profiling analysis provide insights into the biosynthesis of ginsenoside in Panax quinquefolium [0.03%]
整合SMRT测序和人参皂苷谱分析为五叶参中的人参皂苷生物合成提供见解
Peng DI,Yan Yan,Ping Wang et al.
Peng DI et al.
Panax quinquefolium is one of the most common medicinal plants worldwide. Ginsenosides are the major pharmaceutical components in P. quinquefolium. The biosynthesis of ginsenosides in different tissues of P. quinquefolium remained largely u...
Effect of astragaloside IV and salvianolic acid B on antioxidant stress and vascular endothelial protection in the treatment of atherosclerosis based on metabonomics [0.03%]
基于代谢组学的黄酮类化合物和茋类化合物对动脉粥样硬化氧化抗氧化状态及血管内皮保护作用的影响研究
Xiang-Lin Kong,Qin Lyu,Ya-Qi Zhang et al.
Xiang-Lin Kong et al.
Vascular endothelial cells and oxidation reduction system play an important role in the pathogenesis of atherosclerosis (AS). If these conditions are disordered, it will inevitably lead to plaque formation and even rupture. Astragaloside IV...
Guanxinning tablet inhibits the interaction between leukocyte integrin Mac-1 and platelet GPIbα for antithrombosis without increased bleeding risk [0.03%]
调脂通脉片通过抑制中性粒细胞Mac-1与血小板GPIbα相互作用发挥抗血栓作用而不增加出血风险
Qin-Qin Yang,Ming-Sun Fang,Jue Tu et al.
Qin-Qin Yang et al.
Recent studies have showed that thrombosis is closely related to leucocytes involved in immunity. Interfering with the binding of leukocyte integrin Mac-1 and platelet GPIbα can inhibit thrombosis without affecting physiological coagulatio...
Youjing granules ameliorate spermatogenesis in rats through regulating the prolifereation of spermatogonial stem cells [0.03%]
育茎颗粒通过调节精原干细胞增殖改善雄性大鼠生精作用
Xu-Ping Jiang,Yao-Xiang Sun,Bin Qiao et al.
Xu-Ping Jiang et al.
Male infertility has evolved from a common reproductive system disease to a major social issue. Youjing granule (YG) is a Chinese medicinal material used as a therapy method for tonifying the kidneys and removing dampness due to its pathoge...
Centranthera grandiflore alleviates alcohol-induced oxidative stress and cell apoptosis [0.03%]
大花千层红素提取物对酒精性氧化应激和细胞凋亡的改善作用
Xin-Mei Gao,Wen-Han Dong,Chun-Lei Xia et al.
Xin-Mei Gao et al.
Alcohol liver disease (ALD) has become a global threat to human health. It is associated with a wide range of liver diseases including alcohol fatty liver, steatosis, fibrosis and cirrhosis, and finally leads to liver cancer and even death....