Natural products targeting NLRP3 inflammasome for metabolic dysfunction-associated fatty liver disease: the known unknowns [0.03%]
针对NLRP3炎性小体的天然产物在代谢紊乱相关脂肪肝病中的作用：已知与未知
Jiahui Meng,Qiqi Wang,Haopeng Wang et al.
Jiahui Meng et al.
Metabolic dysfunction-associated fatty liver disease (MAFLD), characterized by fatty acid overload, secondary chronic inflammation, and fibrosis, has become the most prevalent chronic liver disease globally. While no effective pharmacothera...
Research progress on polysaccharides from medicine and food homology materials in functional foods [0.03%]
药食同源功能性食品多糖研究进展
Dejun Hu,Yifan Zhang,Boyao Li et al.
Dejun Hu et al.
Polysaccharides, a class of complex macromolecules, are distinguished by their diverse biological functions and essential role in functional foods. The distinctive biological activities of polysaccharides from medicine and food homology mat...
The transcriptomic-based disease network reveals synergistic therapeutic effect of total alkaloids from Coptis chinensis and total ginsenosides from Panax ginseng on type 2 diabetes mellitus [0.03%]
基于转录组的疾病网络分析发现黄连生物碱和人参皂苷对2型糖尿病的协同治疗作用
Qian Chen,Shuying Zhang,Xuanxi Jiang et al.
Qian Chen et al.
Coptis chinensis Franch. and Panax ginseng C. A. Mey. are traditional herbal medicines with millennia of documented use and broad therapeutic applications, including anti-diabetic properties. However, the synergistic effect of total alkaloi...
Ten new lignans with anti-inflammatory activities from the leaves of Illicium dunnianum [0.03%]
八角枫叶中10个新木脂素类抗炎成分的发现与研究
Ting Li,Xiaoqing He,Dabo Pan et al.
Ting Li et al.
The anti-inflammatory phytochemical investigation of the leaves of Illicium dunnianum (I. dunnianum) resulted in the isolation of five pairs of new lignans (1-5), and 7 known analogs (6-12). The separation of enantiomer mixtures 1-5 to 1a/1...
Diketopiperazines with anti-skin inflammation from marine-derived endophytic fungus Aspergillus sp. and configurational reassignment of aspertryptanthrins [0.03%]
来自海洋内生真菌Aspergillus sp.的抗皮肤炎 diketopiperazine及其构型修正
Jin Yang,Xianmei Xiong,Lizhi Gong et al.
Jin Yang et al.
Two novel diketopiperazines (1 and 5), along with ten known compounds (2-4, 6-12) demonstrating significant skin inflammation inhibition, were isolated from a marine-derived fungus identified as Aspergillus sp. FAZW0001. The structural eluc...
Structurally novel tryptamine-derived alkaloids from the seeds of Peganum harmala and their antiviral activities against respiratory syncytial virus [0.03%]
structurally novel tryptamine生物碱及其抗呼吸道合胞病毒活性
Zhongnan Wu,Yubo Zhang,Guocai Wang et al.
Zhongnan Wu et al.
Peganum harmala L. (P. harmala) is a significant economic and medicinal plant. The seeds of P. harmala have been extensively utilized in traditional Chinese medicine, Uighur medicine, and Mongolian medicine, as documented in the Drug Standa...
Dimeric sesquiterpenoids with anti-inflammatory activities from Inula britannica [0.03%]
红升麻中的二聚倍半萜及其抗炎活性研究
Juan Zhang,Jiankun Yan,Hongjun Dong et al.
Juan Zhang et al.
In continuation of research aimed at identifying anti-inflammatory agents from natural sesquiterpenoids, an activity-guided fractionation approach utilizing lipopolysaccharide (LPS)-mediated RAW264.7 cells was employed to investigate chemic...
New tetrahydroanthraquinones and γ-butenolides from the fungus Auxarthron umbrinum DSM3193 [0.03%]
来源于 Auxarthron umbrinum 的四氢蒽酮和γ-丁内酯类化合物
Ling Tian,Bingyu Liu,Qian Wei et al.
Ling Tian et al.
Nine novel compounds, comprising seven tetrahydroanthraquinones (auxarthrolones A-G, 1-7), a γ-butenolide glycoside (malfilamentoside E, 26), and a γ-butenolide (auxarthrolide A, 27), together with eighteen known compounds (8-25) were iso...
Lirispirolides A-L, a new class of sesquiterpene-monoterpene heterodimers with anti-neuroinflammatory activity from the rare medicinal plant Liriodendron chinense [0.03%]
中国鹅掌揪罕见药用植物中的色烷酮单体间嵌合衍生物新类Lirispirolides A-L及其抗神经炎症作用
Yuhang He,Kexin Li,Yufei Wu et al.
Yuhang He et al.
Lirispirolides A-L (1-12), twelve novel sesquiterpene-monoterpene heterodimers featuring distinctive carbon skeletons, were isolated from the branches and leaves of Chinese tulip tree [Liriodendron chinense (L. chinense)], a rare medicinal ...
(±)-Talapyrones A-F: six pairs of dimeric polyketide enantiomers with unusual 6/6/6 and 6/6/6/5 ring systems from Talaromycesadpressus [0.03%]
来自青霉属塔拉菌的六对具有独特6/6/6和6/6/6/5环系统的二聚茋衍生物(±)塔拉吡酮A-F
Meijia Zheng,Xinyi Zhao,Chenxi Zhou et al.
Meijia Zheng et al.
(±)-Talapyrones A-F (1-6), six pairs of dimeric polyketide enantiomers featuring unusual 6/6/6 and 6/6/6/5 ring systems, were isolated from the fungus Talaromyces adpressus. Their structures were determined by spectroscopic analysis and HR...