Physiological and transcriptional responses to heat stress in a typical phenotype of Pinellia ternata [0.03%]
热应激下半夏典型表型的生理及转录组响应分析
Jialu Wang,Jialei Chen,Xiangyu Zhang et al.
Jialu Wang et al.
Pinellia ternata is an important medicinal plant, and its growth and development are easily threatened by high temperature. In this study, comprehensive research on physiological, cytological and transcriptional responses to different level...
Anti-inflammatory sesquiterpene polyol esters from the stem and branch of Tripterygium wilfordii [0.03%]
来自白花蛇舌草茎和枝条的抗炎倍半萜聚醇酯类化合物
Yalin Hu,Tianqi Xu,Wenjing Yin et al.
Yalin Hu et al.
The stem and branch extract of Tripterygium wilfordii (Celastraceae) afforded seven new dihydroagarofuran sesquiterpene polyesters [tripterysines A-G (1-7)] and eight known ones (8-15). The chemical structures of these new compounds were es...
Rong Wang,Lulu Wang,Manli Zhang et al.
Rong Wang et al.
Five new spirostanol saponins (1-5) and seven known compounds (6-12) were isolated from the n-butanol fraction of 75% ethanol extract of Allii Macrostemonis Bulbus. The identification and structural elucidation of all the isolates were perf...
Comprehensive chemical profiling and quantitative analysis of ethnicYi medicine Miao-Fu-Zhi-Tong granules using UHPLC-MS/MS [0.03%]
一种民族药物苗肤止痛颗粒的全面化学轮廓及UHPLC-MS/MS定量分析方法
Xiaoying Lei,Chen Zhang,Suqing Zhao et al.
Xiaoying Lei et al.
Developing analytical methods for the chemical components of natural medicines remains a challenge due to its diversity and complexity. Miao-Fu-Zhi-Tong (MFZT) granules, an ethnic Yi herbal prescription, comprises 10 herbs and has been clin...
Hepatic metabolomics combined with network pharmacology to reveal the correlation between the anti-depression effect and nourishing blood effect of Angelicae Sinensis Radix [0.03%]
网络药理学结合肝代谢组学研究当归补血作用与抗抑郁效应相关性
Wenxia Gong,Shaohua Xu,Yapeng Song et al.
Wenxia Gong et al.
Angelicae Sinensis Radix (AS) is reproted to exert anti-depression effect (ADE) and nourishing blood effect (NBE) in a rat model of depression. The correlation between the two therapeutic effects and its underlying mechanisms deserves furth...
Maackiain inhibits proliferation and promotes apoptosis of nasopharyngeal carcinoma cells by inhibiting the MAPK/Ras signaling pathway [0.03%]
马鞍酸通过抑制MAPK/Ras信号转导途径抑制鼻咽癌细胞的增殖并促进其凋亡
Xing Jiang,Xiaonan Yang,Yanxia Shi et al.
Xing Jiang et al.
Nasopharyngeal carcinoma (NPC) is the third most common malignancy with a high recurrence and metastasis rate in South China. Natural compounds extracted from traditional Chinese herbal medicines have been developed and utilized for the tre...
Exosomes derived from Nr-CWS pretreated MSCs facilitate diabetic wound healing by promoting angiogenesis via the circIARS1/miR-4782-5p/VEGFA axis [0.03%]
Nr-CWS预处理的MSCs衍生的外泌体通过circIARS1/miR-4782-5p/VEGFA轴促进血管生成从而促进糖尿病伤口愈合
Qiang Li,Lei Guo,Jian Wang et al.
Qiang Li et al.
Mesenchymal stem cell (MSC)-derived exosomes (Exos) were reported to a prospective candidate in accelerating diabetic wound healing due to their pro-angiogenic effect. MSCs pretreated with chemistry or biology factors were reported to advan...
10,11-Dehydrocurvularin attenuates inflammation by suppressing NLRP3 inflammasome activation [0.03%]
10，11-去氢曲霉素通过抑制NLRP3炎性小体活化来减轻炎症反应
Qun Zhao,Mengyuan Feng,Shu Jin et al.
Qun Zhao et al.
10,11-Dehydrocurvularin (DCV) is a natural-product macrolide that has been shown to exert anti-inflammatory activity. However, the underlying mechanism of its anti-inflammatory activity remains poorly understood. Aberrant activation of the ...