Puerarin inhibits inflammation and lipid accumulation in alcoholic liver disease through regulating MMP8 [0.03%]
葛根素通过调节MMP8抑制酒精性肝病炎症和脂质蓄积
Ying Hu,Shuxian Wang,Lan Wu et al.
Ying Hu et al.
Alcoholic liver disease (ALD) is a growing global health concern, and its early pathogenesis includes steatosis and steatohepatitis. Inhibiting lipid accumulation and inflammation is a crucial step in relieving ALD. Evidence shows that puer...
Research progress on the pharmacological effects and chemical constituents of Pien Tze Huang and its potential Q-markers [0.03%]
皮诺黄药理效应及化学成分研究进展和潜在质量标志物探讨
Zhaomin Dong,Hong Wang,Guangji Wang
Zhaomin Dong
Pien Tze Huang (PTH) was documented as an imperial prescription composed of Notoginseng Radix, Calculus Bovis, Snake Gallbladder, and Musk. It is famous in China and Asian countries due to its excellent effects in heat clearing, detoxifying...
Therapeutic potential and mechanism of Chinese herbal medicines in treating fibrotic liver disease [0.03%]
中药治疗肝纤维化的疗效及机制研究
Yanwei Li,Yunrui Lu,Mozuo Nian et al.
Yanwei Li et al.
Liver fibrosis is a pathological condition characterized by replacement of normal liver tissue with scar tissue, and also the leading cause of liver-related death worldwide. During the treatment of liver fibrosis, in addition to antiviral t...
Targeted trace ingredients coupled with chemometric analysis for consistency evaluation of Panax notoginseng saponins injectable formulations [0.03%]
基于化学生物学的三七注射液一致性评价中的指标成分与化学计量学方法研究
Jingxian Zhang,Zijia Zhang,Zhaojun Wang et al.
Jingxian Zhang et al.
Evaluating the consistency of herb injectable formulations could improve their product quality and clinical safety, particularly concerning the composition and content levels of trace ingredients. Panax notoginseng Saponins Injection (PNSI)...
Antimalarial and neuroprotective ent-abietane diterpenoids from the aerial parts of Phlogacanthus curviflorus [0.03%]
Phlogacanthus curviflorus地上部分中具有抗疟和神经保护作用的ent-abies烷二萜类化合物
Jia Li,Xiao Meng,Chengyue Yin et al.
Jia Li et al.
Six new ent-abietane diterpenoids, abientaphlogatones A-F (1-6), along with two undescribed ent-abietane diterpenoid glucosides, abientaphlogasides A-B (7-8) and four known analogs were isolated from the aerial parts ofPhlogacanthus curvifl...
2,3-Seco and 3-nor guaianolides fromAchillea alpina with antidiabetic activity [0.03%]
具有抗糖尿病活性的Achillea alpina中的2,3-塞考和3-诺guaianolides成分
Guimin Xue,Chenguang Zhao,Jinfeng Xue et al.
Guimin Xue et al.
In this study, we presented the isolation and characterization of eight novel seco-guaianolide sesquiterpenoids (1-8) and two known guaianolide derivatives (9 and 10), from the aerial part of Achillea alpina L.. Compounds 1-3 were identifie...
Dammarane-type triterpenoid saponins isolated from Gynostemma pentaphyllum ameliorate liver fibrosis via agonizing PP2Cα and inhibiting deposition of extracellular matrix [0.03%]
绞股蓝五叶参中的达玛烷型三萜皂苷通过激动PP2Cα和抑制细胞外基质沉积改善肝纤维化
Yue Liu,Yating Yang,Hanghang Wang et al.
Yue Liu et al.
Gypenosides, structurally analogous to ginsenosides and derived from a sustainable source, are recognized as the principal active compounds found in Gynostemma pentaphyllum, a Chinese medicinal plant used in the treatment of the metabolic s...
Total glucosides of Rhizoma Smilacis Glabrae: a therapeutic approach for psoriasis by regulating Th17/Treg balance [0.03%]
total glucosides of rhizoma smilacis glabrae通过调节th17/treg平衡治疗银屑病
Yingzhan Tang,Jingyi Yu,Wen Zhao et al.
Yingzhan Tang et al.
Total glucosides of Rhizoma Smilacis Glabrae (RSG) are selective immunosuppressants that exhibit primary efficacy in the treatment of rheumatoid arthritis through targeted inhibition of activated T cells. In this study, we aimed to investig...
Xuebijing alleviates LPS-induced acute lung injury by downregulating pro-inflammatory cytokine production and inhibiting gasdermin-E-mediated pyroptosis of alveolar epithelial cells [0.03%]
雪贝金通过下调促炎细胞因子的产生和抑制气管导膜-D介导的肺泡上皮细胞焦亡来缓解脂多糖诱导的大鼠急性肺损伤作用研究
Cuiping Zhang,Xiaoyan Chen,Tianchang Wei et al.
Cuiping Zhang et al.
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is characterized by diffuse alveolar injury primarily caused by an excessive inflammatory response. Regrettably, the lack of effective pharmacotherapy currently available cont...