Potential role of Natural Herbal Tea as a healthy beverage in reducing the risk of liver cancer and chronic liver disease mortality [0.03%]
天然草本茶作为健康饮料在降低肝癌和慢性肝病死亡风险中的潜在作用
Xiaoying Hou,Yuchen Liu,Hongzhi DU
Xiaoying Hou
Utilizing natural products as new E3 ligase ligands for targeted protein degradation [0.03%]
利用天然产物作为新的E3连接酶配体用于靶向蛋白质降解
Yanan Gong,Saiqi Wang,Xiao-Bing Chen et al.
Yanan Gong et al.
Thirteen new peptaibols with antimicrobial activities from Trichoderma sp [0.03%]
来自尖孢镰刀菌的具有抗菌活性的13种新肽苔醇类化合物
Pan Tang,Dan Huang,Kai-Xuan Zheng et al.
Pan Tang et al.
From the fungus Trichoderma sp., we isolated seven novel 18-residue peptaibols, neoatroviridins E-K (1-7), and six new 14-residue peptaibols, harzianins NPDG J-O (8-13). Additionally, four previously characterized 18-residue peptaibols neoa...
Asponchimides A-E: new enantiomeric N-acetyldopamine trimers from Aspongopus chinensis [0.03%]
来自中国海海绵Aspongopus chinensis中新多胺类生物碱aspochimides A–E
Jinchun Nie,Fang Mei,Yueyuan Zheng et al.
Jinchun Nie et al.
Five new racemic N-acetyldopamine (NADA) trimers, asponchimides A-E (1-5), were isolated from Aspongopus chinensis, a prominent traditional Chinese medicinal insect employed for alleviating pain, treating indigestion, and addressing kidney ...
Six new coumarins from the roots of Toddalia asiatica and their anti-inflammatory activities [0.03%]
Toddalia asiatica根的新香豆素类成分及其抗炎活性研究
Haoxuan He,Niping Li,Yunqi Fan et al.
Haoxuan He et al.
We reported the discovery of six novel coumarins, toddasirins A-F (1-6), each endowed with modified isoprenyl or geranyl side chains, derived from the roots of Toddalia asiatica. Comprehensive structural elucidation was achieved through mul...
Identification of Bulbocodin D and C as novel STAT3 inhibitors and their anticancer activities in lung cancer cells [0.03%]
从防己族化合物中鉴定新的STAT3抑制剂及其在肺癌细胞中的抗肿瘤活性研究
Xinyu He,Jiarui Fu,Wenyu Lyu et al.
Xinyu He et al.
Cancer stands as one of the predominant causes of mortality globally, necessitating ongoing efforts to develop innovative therapeutics. Historically, natural products have been foundational in the quest for anticancer agents. Bulbocodin D (...
SBC (Sanhuang Xiexin Tang combined with Baihu Tang plus Cangzhu) alleviates NAFLD by enhancing mitochondrial biogenesis and ameliorating inflammation in obese patients and mice [0.03%]
黄褐泻心汤合白虎加苍术汤通过促进线粒体生物发生及减轻炎症缓解肥胖相关非酒精性脂肪肝病
Zhitao Ren,Gemin Xiao,Yixin Chen et al.
Zhitao Ren et al.
In the context of non-alcoholic fatty liver disease (NAFLD), characterized by dysregulated lipid metabolism in hepatocytes, the quest for safe and effective therapeutics targeting lipid metabolism has gained paramount importance. Sanhuang X...
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway [0.03%]
桑叶黄酮通过调节AMPK/SIRT1/PGC-1α信号通路激活BAT并诱导WAT褐变改善2型糖尿病
Long Cheng,Lu Shi,Changhao He et al.
Long Cheng et al.
Mulberry (Morus alba L.) leaf is a well-established traditional Chinese botanical and culinary resource. It has found widespread application in the management of diabetes. The bioactive constituents of mulberry leaf, specifically mulberry l...
Anti-hepatitis B virus activities of natural products and their antiviral mechanisms [0.03%]
天然产物的抗乙肝病毒活性及抗病毒机制研究
Wanyu Deng,Fu Chen,Yue Zhao et al.
Wanyu Deng et al.
Chronic hepatitis B (CHB) infections caused by the hepatitis B virus (HBV) continue to pose a significant global public health challenge. Currently, the approved treatments for CHB are limited to interferon and nucleos(t)ide analogs, both o...
The thalamic-primary auditory cortex circuit: a pathway to resilience in the face of stress and a potential target for depression treatment [0.03%]
丘脑-听皮层环路在应激抵抗及抑郁症治疗中的作用
Jianling Tan,Ling Ye
Jianling Tan