Polysaccharides from Chinese herbal medicine: a review on the hepatoprotective and molecular mechanism [0.03%]
中药中的多糖：保肝作用及其分子机制综述
Jifeng Li,Haolin Guo,Ying Dong et al.
Jifeng Li et al.
Polysaccharides, predominantly extracted from traditional Chinese medicinal herbs such as Lycium barbarum, Angelica sinensis, Astragalus membranaceus, Dendrobium officinale, Ganoderma lucidum, and Poria cocos, represent principal bioactive ...
Si-Wu-Tang attenuates liver fibrosis via regulating lncRNA H19-dependent pathways involving cytoskeleton remodeling and ECM deposition [0.03%]
四物汤通过调节依赖长链非编码RNA H19的细胞骨架重构和ECM沉积途径减轻肝纤维化
Jiaorong Qu,Xiaoyong Xue,Zhixing Wang et al.
Jiaorong Qu et al.
Liver fibrosis is a dynamic wound-healing response characterized by the agglutination of the extracellular matrix (ECM). Si-Wu-Tang (SWT), a traditional Chinese medicine (TCM) formula, is known for treating gynecological diseases and liver ...
A review of structural modification and biological activities of oleanolic acid [0.03%]
乌苏酸的结构修饰及其生物活性研究进展
Huali Yang,Minghui Deng,Hongwei Jia et al.
Huali Yang et al.
Oleanolic acid (OA), a pentacyclic triterpenoid, exhibits a broad spectrum of biological activities, including antitumor, antiviral, antibacterial, anti-inflammatory, hepatoprotective, hypoglycemic, and hypolipidemic effects. Since its init...
Tu-Xian Decoction ameliorates diabetic cognitive impairment by inhibiting DAPK-1 [0.03%]
吐泻 decoction 通过抑制 DAPK-1 改善糖尿病认知障碍
Danyang Wang,Bin Yan,An Wang et al.
Danyang Wang et al.
Tu-Xian decoction (TXD), a traditional Chinese medicine (TCM) formula, has been frequently administered to manage diabetic cognitive impairment (DCI). Despite its widespread use, the mechanisms underlying TXD's protective effects on DCI hav...
Functional characterization of CYP81C16 involved in the tanshinone biosynthetic pathway in Salvia miltiorrhiza [0.03%]
鼠尾草中丹参酮生物合成通路相关基因CYP81C16的的功能分析
Li Ren,Linglong Luo,Zhimin Hu et al.
Li Ren et al.
Danshen, the dried roots and rhizomes of Salvia miltiorrhiza Bunge (S. miltiorrhiza), is widely used in the treatment of cardiovascular and cerebrovascular diseases. Tanshinones, the bioactive compounds from Danshen, exhibit a wide spectrum...
Shanshan Zhang,Xudong Mao,Hongtao Xu et al.
Shanshan Zhang et al.
Six new abietane diterpenoids (1-6) and five undescribed iridoids (7-11) have been isolated from the aerial parts of Caryopteris mongolica. The intricate structural characterization of these compounds was meticulously undertaken using an ar...
Discovery and bioassay of disubstituted β-elemene-NO donor conjugates: synergistic enhancement in the treatment of leukemia [0.03%]
双取代β-姜烯-NO供体偶联物的发现及其生物测定：在白血病治疗中表现出协同增强作用
Junlong Zhu,Xiaoying Jiang,Xinyu Luo et al.
Junlong Zhu et al.
Natural products are essential sources of antitumor drugs. One such molecule, β-elemene, is a potent antitumor compound extracted from Curcuma wenyujin. In the present investigation, a series of novel 13,14-disubstituted nitric oxide (NO)-...
Artemdubinoids A-N: novel sesquiterpenoids with antihepatoma cytotoxicity from Artemisia dubia [0.03%]
来自黄花蒿的具有抗肝癌细胞毒性的新型倍半萜(artermDubinoid a-n)
Zhen Gao,Tianze Li,Yunbao Ma et al.
Zhen Gao et al.
In pursuit of effective agents for hepatocellular carcinoma derived from the Artemisia species, this study built upon initial findings that an ethanol (EtOH) extract and ethyl acetate (EtOAc) fraction of the aerial parts of Artemisia dubia ...
Chemical approaches for the stereocontrolled synthesis of 1,2-cis-β-D-rhamnosides [0.03%]
1,2-顺式-β-D-鼠李糖苷的立体控制合成的化学方法
Juntao Cai,Xin Yuan,Yuanfang Kong et al.
Juntao Cai et al.
In carbohydrate chemistry, the stereoselective synthesis of 1,2-cis-glycosides remains a formidable challenge. This complexity is comparable to the synthesis of 1,2-cis-β-D-mannosides, primarily due to the adverse anomeric and Δ-2 effects...