Three rare anti-inflammatory sesquiterpene lactones from Magnolia grandiflora [0.03%]
Magnolia grandiflora的三种稀有抗炎倍半萜内酯成分研究
Shuangyu Xu,Feng Zhang,Linlan Tao et al.
Shuangyu Xu et al.
Four new sesquiterpene lactones (SLs) (1-4), along with a biosynthetically related SL (5), have been isolated from the leaves of Magnolia grandiflora. Magrandate A (1) is notable as the first C18 homogemarane type SL, featuring a unique 1,7...
An inulin-type fructan CP-A from Codonopsis pilosula attenuates experimental colitis in mice by promoting autophagy-mediated inactivation of NLRP3 inflammasome [0.03%]
北沙参多聚果糖CP-A通过促进自噬抑制NLRP3炎症小体活化从而缓解实验性结肠炎
Jiangtao Zhou,Jun Wang,Jiajing Wang et al.
Jiangtao Zhou et al.
Inulin-type fructan CP-A, a predominant polysaccharide in Codonopsis pilosula, demonstrates regulatory effects on immune activity and anti-inflammation. The efficacy of CP-A in treating ulcerative colitis (UC) is, however, not well-establis...
Carrimycin ameliorates lipopolysaccharide and cecal ligation and puncture-induced sepsis in mice [0.03%]
卡利霉素改善脂多糖和盲肠结扎穿孔引起的鼠脓毒症
Junzhong Lai,Jiadi Liang,Kunsen Chen et al.
Junzhong Lai et al.
Carrimycin (CA), sanctioned by China's National Medical Products Administration (NMPA) in 2019 for treating acute bronchitis and sinusitis, has recently been observed to exhibit multifaceted biological activities, encompassing anti-inflamma...
Yanggan Jiangmei Formula alleviates hepatic inflammation and lipid accumulation in non-alcoholic steatohepatitis by inhibiting the NF-κB/NLRP3 signaling pathway [0.03%]
养肝ManagerInterface_formula通过抑制NF-κB/NLRP3信号通路缓解非酒精性脂肪肝病小鼠的肝脏炎症和脂质蓄积
Yuanyuan Wu,Jingwen Zhou,Xinchen Zuo et al.
Yuanyuan Wu et al.
The role of NF-κB and the NLRP3 inflammasome in the chronic inflammatory microenvironment of non-alcoholic steatohepatitis (NASH) has been posited as crucial. The Yanggan Jiangmei Formula (YGJMF) has shown promise in ameliorating hepatic s...
Ethanol extract of Cyathulae Radix inhibits osteoclast differentiation and bone loss [0.03%]
制川乌提取物抑制破骨细胞分化和骨质流失的作用及机制研究
Liying Shi,Liuyi Ren,Jinping Li et al.
Liying Shi et al.
Cyathulae Radix, a traditional Chinese medicine and a common vegetable, boasts a history spanning millennia. It enhances bone density, boosts metabolism, and effectively alleviates osteoporosis-induced pain. Despite its historical use, the ...
Zhongwen Luo,Fucheng Yin,Xiaobing Wang et al.
Zhongwen Luo et al.
Natural products (NPs) have consistently played a pivotal role in pharmaceutical research, exerting profound impacts on the treatment of human diseases. A significant proportion of approved molecular entity drugs are either directly derived...
Huiwen Dong,Huiming Ge
Huiwen Dong
Chen Zhang,Jianbing Wu,Yihua Zhang et al.
Chen Zhang et al.
Composition analysis of Compound Shenhua Tablet, a seven-herb Chinese medicine for IgA nephropathy: evaluation of analyte-capacity of the assays [0.03%]
七味中药复方肾华片的组成分析：评估测定方法的容量和分析物
Haiyan Zhang,Qiuyue Wang,Jianan Wang et al.
Haiyan Zhang et al.
Compound Shenhua Tablet, a medicine comprising seven herbs, is employed in treating IgA nephropathy. This study aimed to meticulously analyze its chemical composition. Based on a list of candidate compounds, identified through extensive lit...
Shengge Li,Qin Zhang,Yuetong Wang et al.
Shengge Li et al.
This study reports the isolation of four new β-carboline alkaloids (1-4) and six previously identified alkaloids (5-10) from the roots of Peganum harmala L. Among these compounds, 1 and 2 were characterized as rare β-carboline-quinazoline...