Cancer statistics and trends in China: the potential of natural product application [0.03%]
中国癌症统计和趋势：天然产物的应用潜力
Ting Li,Muyang Huang,Jinjian Lu
Ting Li
Molecular quantification of herbs (Herb-Q): a pyrosequencing-based approach and its application in Pinellia ternata [0.03%]
基于焦磷酸测序的中药分子定量技术（Herb-Q）及其在半夏中的应用研究
Yifei Pei,Ziyi Liu,Dade Yu et al.
Yifei Pei et al.
Variations in herb dosage due to species adulteration and dosing inaccuracies can substantially affect clinical safety and efficacy. Accurate species quantification remains challenging, as current methods often yield inconsistent results. T...
Mengsha Wei,Weiguang Sun,Linlin Liu et al.
Mengsha Wei et al.
Spectasterols F-O (1-10), ten interesting ergosterols with an aromatized B ring, were obtained from Aspergillus spectabilis. Their structures and absolute configurations were determined using a combination of high-resolution electrospray io...
Structure-guided isolation of anti-neuroinflammatory sesquiterpene coumarins from Ferula sinkiangensis [0.03%]
结构导向从费伦塞品中分离抗神经炎症倍半萜香豆素化合物
Wen Dang,Tingting Guo,Di Zhou et al.
Wen Dang et al.
The resin of Ferula sinkiangensis has been traditionally utilized for treating gastrointestinal disorders, inflammation, tumors, various cancers, and alopecia areata. The primary bioactive constituents, sesquiterpene coumarins, have demonst...
Gambogenic acid induces apoptosis via upregulation of Noxa in oral squamous cell carcinoma [0.03%]
gambogenic酸通过上调Noxa诱导口腔鳞状细胞癌细胞凋亡
Xinran Cheng,Mengyuan Feng,Anjie Zhang et al.
Xinran Cheng et al.
Gambogenic acid (GNA), a bioactive compound derived from the resin of Garcinia hanburyi, has demonstrated significant antitumor properties. However, its mechanisms of action in oral squamous cell carcinoma (OSCC) remain largely unclear. Thi...
Inonotus obliquus (Chaga) against HFD/STZ-induced glucolipid metabolism disorders and abnormal renal functions by regulating NOS-cGMP-PDE5 signaling pathway [0.03%]
斜卧小孔菌（茶瓜）通过调节NOS-cGMP-PDE5信号通路对抗HFD / STZ诱导的糖脂代谢障碍和异常肾功能
Yating Feng,Jing Liu,Le Gong et al.
Yating Feng et al.
Our prior investigations have established that Inonotus obliquus (Chaga) possesses hypoglycemic effects. Persistent hyperglycemia is known to precipitate renal function abnormalities. The functionality of the kidneys is intricately linked t...
Periplaneta americana extract promotes infectious diabetic ulcers wound healing by downregulation of LINC01133/SLAMF9 [0.03%]
美洲蜚蠊提取物通过下调LINC01133/SLAMF9促进感染性糖尿病足溃疡的愈合
Yuhang Yang,Jun Huang,Xintian Li et al.
Yuhang Yang et al.
Wound healing in diabetic ulcers remains a significant clinical challenge, primarily due to bacterial infection and impaired angiogenesis. Periplaneta americana extract (PAE) has been widely used to treat diabetic wounds, yet its underlying...
Korean red ginseng alleviates benign prostatic hyperplasia by dysregulating androgen receptor signaling and inhibiting DRP1-mediated mitochondrial fission [0.03%]
韩国红人参通过调节雄激素受体信号和抑制DRP1介导的线粒体分裂来缓解良性前列腺增生
Geum-Lan Hong,Kyung-Hyun Kim,Sung-Pil Cho et al.
Geum-Lan Hong et al.
Panax ginseng (C.A. Mey.) has been traditionally employed in Korea and China to alleviate fatigue and digestive disorders. In particular, Korean red ginseng (KRG), derived from streamed and dried P. ginseng, is known for its anti-aging and ...
Picroside II promotes HSC apoptosis and inhibits the cholestatic liver fibrosis in Mdr2-/- mice by polarizing M1 macrophages and balancing immune responses [0.03%]
穿心莲内酯衍生物II通过极化M1型巨噬细胞平衡免疫反应促进HSC凋亡并抑制Mdr2-/-小鼠胆汁淤积性肝纤维化
Kexin Jia,Zhi Ma,Yinhao Zhang et al.
Kexin Jia et al.
Liver fibrosis is characterized by chronic inflammatory responses and progressive fibrous scar formation. Macrophages play a central role in the pathogenesis of hepatic fibrosis by reconstructing the immune microenvironment. Picroside II (P...