Active herbal ingredients and drug delivery design for tumor therapy: a review [0.03%]
用于肿瘤治疗的植物活性成分和药物递送设计综述
Jing Han,Yanxi Shen,Ruiying Cao et al.
Jing Han et al.
Active herbal ingredients are gaining recognition for their potent anti-tumor efficacy, attributable to various mechanisms including tumor cell inhibition, immune system activation, and tumor angiogenesis inhibition. Recent studies have rev...
Hongxin Chen,Xiaoyu Su,Yijuan Luo et al.
Hongxin Chen et al.
Essential oils (EOs) are natural, volatile substances derived from aromatic plants. They exhibit multiple pharmacological effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant properties, with broad application pr...
Xiaotong Li,Yaoyao Lai,Guanghan Wan et al.
Xiaotong Li et al.
In recent years, there has been an increasing emphasis on exploring innovative drug delivery approaches due to the limitations of conventional therapeutic strategies, such as inadequate drug targeting, insufficient therapeutic efficacy, and...
Glycyrrhizic acid-based multifunctional nanoplatform for tumor microenvironment regulation [0.03%]
甘草酸基多功能纳米平台用于肿瘤微环境调节
Meng Xiao,Zhiqing Guo,Yating Yang et al.
Meng Xiao et al.
Natural compounds demonstrate unique therapeutic advantages for cancer treatment, primarily through direct tumor suppression or interference with the tumor microenvironment (TME). Glycyrrhizic acid (GL), a bioactive ingredient derived from ...
Minghui Li,Yihua Xu,Yanan Yu et al.
Minghui Li et al.
Atopic dermatitis (AD) is a chronic inflammatory skin condition. Natural products have gained traction in AD treatment due to their accessibility, low toxicity, and favorable pharmacological properties. However, their application is primari...
Advances in the combination of stem cell exosomes with medical devices-the new direction for combination products [0.03%]
干细胞外泌体与医疗器械结合的研究进展——组合产品新方向
Yuewen Zhai,Fang He,Ji Fang et al.
Yuewen Zhai et al.
Exosomes (exos), nanoscale extracellular vesicles, play a critical role in tissue development and function. Stem cell-derived exos, containing various tissue repair components, show promise as natural therapeutic agents in disease treatment...
Wei He,Yujie Shi,Ding Qu
Wei He
Luteolin ameliorates ulcerative colitis in mice via reducing the depletion of NCR+ILC3 through Notch signaling pathway [0.03%]
黄芩素通过 notch 信号通路减少 NCR+ILC3 耗竭从而改善小鼠溃疡性结肠炎
Xueqian Xie,Pengcheng Li,Meng Zhao et al.
Xueqian Xie et al.
The disorder of group 3 innate lymphoid cells (ILC3) subgroup, such as the predominance of NCR-ILC3 but the depletion of NCR+ILC3, is unfavorable to damaged intestinal barrier repair, which leads to the prolongations and obstinacy of ulcera...
Loganin inhibits the ROS-NLRP3-IL-1β axis by activating the NRF2/HO-1 pathway against osteoarthritis [0.03%]
loganin通过激活NRF2/HO-1途径抑制ROS-NLRP3-IL-1β轴对抗骨关节炎
Miao Li,Jiacong Xiao,Baihao Chen et al.
Miao Li et al.
Loganin (LOG), a bioactive compound derived from Cornus officinalis Siebold & Zucc, has been understudied in the context of osteoarthritis (OA) treatment. In this study, we induced an inflammatory response in chondrocytes using lipopolysacc...
Dual-function natural products: Farnesoid X receptor agonist/inflammation inhibitor for metabolic dysfunction-associated steatotic liver disease therapy [0.03%]
兼具双功能的天然产物：法尼醇X受体激动剂/炎症抑制剂用于防治非酒精性脂肪肝病
Kang Wang,Pengfei Zhang,Huiyong Sun et al.
Kang Wang et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease globally, with only one Food and Drug Administration (FDA)-approved drug for its treatment. Given MASLD's complex pathophysiology, ...