Anticancer compounds from Streptomyces: insights from metagenomics and mechanistic perspective [0.03%]
从元基因组学和机制角度浅析链霉菌的抗肿瘤化合物
Muhanna Mohammed Al-Shaibani,Noraziah Mohamad Zin,Juwairiah Remali et al.
Muhanna Mohammed Al-Shaibani et al.
Cancer continues to be a leading cause of death globally, driving the ongoing search for novel bioactive compounds with therapeutic potential. Metagenomic sequencing has revolutionized this pursuit by enabling the direct detection and genom...
Metabarcoding reveals unique rhizospheric microbiomes of Rhizophora in Indian Mangroves [0.03%]
元条形码技术揭示了印度红树 mangrove中Rhizophora的独特的根际微生物群落
V Kavi Sidharthan,Ruby Patel,Muthuprasad Thiyaharajan et al.
V Kavi Sidharthan et al.
Rhizophora species are ecologically significant true mangroves with a broad tropical distribution. We examined the rhizospheric microbiomes of dominant Rhizophora species from two contrasting Indian mangrove ecosystems-Coringa and Pichavara...
β-Glucan in antiviral defense: mechanisms, immune modulation, and therapeutic prospects [0.03%]
β-葡聚糖在抗病毒防御中的作用：机制、免疫调节和治疗前景
Ali M Atoom,Waleed K Abdulsahib,S Renuka Jyothi et al.
Ali M Atoom et al.
β-Glucans, naturally occurring β-D-glucose polysaccharides from fungi, yeast, bacteria, algae, and cereals, have emerged as promising immunomodulatory agents in antiviral defense. Their structural diversity-encompassing β-1,3, β-1,6, an...
hMPV co-infections: Distinct immunopathogenic mechanisms and clinical implications of viral and bacterial pathogenesis [0.03%]
人多瘤病毒合并感染：病毒和细菌病原学的免疫病理机制及临床意义
Syed Sib Tul Hassan Shah,Iqra Naeem,Nabeel Khalid Bhutta et al.
Syed Sib Tul Hassan Shah et al.
Human metapneumovirus (hMPV) co-infections with viral and bacterial pathogens are increasingly recognized as major contributors to severe respiratory disease, especially in children, older adults, and immunocompromised individuals. This rev...
Effect of continuous cropping on bacterial and fungal communities in Glehnia littoralis soil [0.03%]
连作对北沙参根际细菌和真菌群落的影响
Zhengpu Rong,Jingqiao Zhao,Weihong Shi et al.
Zhengpu Rong et al.
Rhizosphere soil microorganisms are critical in the plant's growth and soil health. Continuous cropping had significant effects on rhizosphere soil microbial community. This study used Glehnia littoralis of 1-year (primary soil, FS), 2-year...
Microbiome-based approaches to personalized nutrition: from gut health to disease prevention [0.03%]
基于微生物组的个性化营养方法：从肠道健康到疾病预防
Parveen Nisa,Arivarasan Vishnu Kirthi,Priyobrata Sinha
Parveen Nisa
A complex community of trillions of microorganisms, the human gut microbiome has become a major regulator of health, impacting immune system function, metabolism, digestion, and even brain activity. Recent findings demonstrate how the micro...
Diverse plant growth-promoting bacteria as microsymbionts in nodules of Leucaena leucocephala [0.03%]
在象草根瘤中作为微共生体的多种促生菌
Gaurav Kumar,Anjali Chauhan,Shubham Sharma et al.
Gaurav Kumar et al.
This study characterized 18 endophytic bacterial isolates in association with the root nodules of Leucaena leucocephala through phenotypic and genotypic analyses. The endophytes were associated with the plants and exhibited diverse plant gr...
Exploring the impact of quercetin on the growth and biofilm formation of Leptospira interrogans [0.03%]
探究槲皮素对问号钩端螺旋体生长及生物被膜形成的影响研究
Elumalai Rajalakshmi,Evangeline Seles J L,Anandkumar Balakrishnan et al.
Elumalai Rajalakshmi et al.
Leptospira interrogans, the causative agent of leptospirosis, presents major challenges due to its ability to form environmental biofilms, persistent virulence, and emerging antimicrobial resistance. Plant-derived bioactive compounds offer ...
The anti-inflammatory drugs diclofenac and ketorolac inhibit urease activity and biofilm formation by uropathogenic Proteus mirabilis [0.03%]
抗炎药氟比洛芬和酮咯酸抑制尿路致病性变形杆菌的尿素酶活性和生物被膜形成能力
Afaf Eladl,Hisham A Abbas,Samar S Elbaramawi et al.
Afaf Eladl et al.
Proteus mirabilis is a major bacterium responsible for catheter-associated urinary tract infections (CAUTIs). Urease enzyme has a great role in the pathogenesis of Proteus mirabilis. Using urease, Proteus mirabilis can decompose urea to pro...
Flurbiprofen restores rifampicin and isoniazid sensitivity in multidrug-resistant Mycobacterium tuberculosis putatively by inhibiting efflux pumps Rv0194 and Rv0933 [0.03%]
氟比洛芬通过抑制Rv0194和Rv0933外排泵恢复耐多药结核分枝杆菌对利福平和异烟肼的敏感性
Padmasini Elango,Christy Rosaline Nirmal,Sam Ebenezer Rajadas et al.
Padmasini Elango et al.
Multidrug-resistant tuberculosis remains a global health challenge, necessitating novel therapeutic approaches. Efflux pumps, including Rv0194 and Rv0933, contribute to Mycobacterium tuberculosis resistance by actively extruding first-line ...