Enhancing okra tolerance to salinity stress: role of PGPR and antioxidant enzymes [0.03%]
植物根际促生菌和抗氧化酶活对锦葵耐盐性的影响研究
Catherine Jose,Subramaniyan S,Sandhia G S
Catherine Jose
Salinity stress is a major constraint on global crop productivity, necessitating sustainable strategies to enhance plant resilience. Plant growth-promoting rhizobacteria (PGPR) with 1-aminocyclopropane-1-carboxylate (ACC) deaminase activity...
Gut allies against metabolic disorders: the therapeutic promise of probiotics [0.03%]
肠道盟友对抗代谢性疾病——益生菌的治疗前景
Tolulope Joshua Ashaolu,Thanh-Do Le
Tolulope Joshua Ashaolu
Physalis peruviana and Lactobacillus lysates as modulators of lipid metabolism and oxidative stress: a natural alternative to statin therapy [0.03%]
用 Physalis peruviana 和乳酸菌提取物调节脂质代谢和氧化应激：一种替代他汀疗法的自然方法
Manal Mused Almatrafi,Alaa H Nada,Ahmed S Doghish et al.
Manal Mused Almatrafi et al.
Hyperlipidemia is a major modifiable risk factor for atherosclerosis and coronary heart disease. Although effective, current pharmacological interventions such as statins are often limited by adverse effects, including muscular pain, gastro...
Therapeutic advances in the fight against microbial resistance: innovative strategies and future challenges [0.03%]
抗微生物药物耐药性战疫中的治疗进展：创新策略与未来挑战
Jonathan Mandú de Araújo,Alícia Natalie Silva Dos Santos,Bruno José da Silva Bezerra et al.
Jonathan Mandú de Araújo et al.
Antimicrobial Resistance (AMR) is characterized by the reduced effectiveness of antibiotics due to the adaptation of microorganisms, which limits therapeutic options and increases the severity of infections. This paper aims to discuss thera...
Structure-guided discovery and validation of a potent RamR inhibitor targeting efflux-mediated multidrug resistance in Salmonella typhimurium [0.03%]
结构指导的RamR抑制剂发现与验证：靶向沙门氏菌外排诱导型多药抗性蛋白
Gopal Prasad Agrawal,Md Shamsher Alam,Faisal Alotaibi et al.
Gopal Prasad Agrawal et al.
The emergence of multidrug-resistant (MDR) strains of Salmonella typhimurium (S. typhimurium) causes a significant global health challenge and underscores the need to develop potential antimicrobial agents. Here, we considered RamR, the maj...
The role of rapid molecular diagnostics in managing bloodstream infections: a microbiological insight [0.03%]
快速分子诊断技术在血流感染管理中的作用：微生物学视角
Jitendra Gupta,Ibrahim Saeed Gataa,Narinderjit Singh Sawaran Singh et al.
Jitendra Gupta et al.
Bloodstream infections (BSIs) represent a significant clinical challenge due to their high morbidity and mortality rates, compounded by the increasing prevalence of antimicrobial resistance (AMR). Even though they are regarded as the gold s...
Impact of ompK35 and ompK36 downregulation on antibiotic resistance in clinical carbapenem-resistant Klebsiella pneumoniae isolates [0.03%]
ompK35和ompK36低表达对临床碳青霉烯耐药肺炎克雷伯菌表型的影响
Davood Kalantar-Neyestanaki,Sajad Aslani,Saba Karimitabar et al.
Davood Kalantar-Neyestanaki et al.
The increase in the prevalence of carbapenem-resistant Klebsiella pneumoniae strains (CRKP) has led to higher mortality and hospitalization of patients in health care facilities. This study investigates the resistance in CRKP, highlighting ...
Nisin: The powerhouse metabolite of lactobacillus strains to defeat prostate cancer by targeting PCA3 lncRNA, apoptosis, and cell cycle pathways [0.03%]
nisin通过靶向PCA3长链非编码RNA、凋亡和细胞周期途径击败前列腺癌
Runheng Zhao,Wenfang Liu,Ke Wang et al.
Runheng Zhao et al.
Prostate cancer remains a major global health challenge, driving the need for innovative therapies. Nisin, an antimicrobial peptide from Lactobacillus lactis, has shown anticancer effects in various malignancies, yet its impact on prostate ...
Modeling and optimization of acid hydrolysis for spirulina-based ethanol production by response surface methodology and neural network techniques [0.03%]
响应面法和神经网络技术在模拟和优化螺旋藻生产乙醇酸水解中的应用
Kavitha M S,Shenbagamuthuraman V,Nallanthighal Harsh Vaibhav et al.
Kavitha M S et al.
The main aim of this study was to evaluate the optimum conditions for extracting the total reducing sugar content for bioethanol production using spirulina algae. The spirulina algae was pretreated using microwave-assisted acid hydrolysis, ...
Targeting multidrug-resistant Escherichia coli by two isolated bacteriophages from hospital wastewater [0.03%]
从医院污水中分离的两种噬菌体针对耐多药的大肠埃希氏菌
Razieh Khalili Rad,Roya Ahmadrajabi,Sanaz Rastegar et al.
Razieh Khalili Rad et al.
The growing emergence of antibiotic resistance has prompted the World Health Organization to include Escherichia coli on its list of global priority pathogens, highlighting the urgent need for new therapeutic strategies. This study was desi...